Cannabis Compound Database: Showing Compound Card for Carbon dioxide (CDB004931)

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Identification Taxonomy Ontology Physical properties Spectra Protein target Pathways Concentrations Links References enzymes (97)transporters (3) Show 147 proteins XML

Record Information

Version

1.0

Created at

2020-04-17 18:51:45 UTC

Updated at

2020-12-07 19:11:18 UTC

CannabisDB ID

CDB004931

Secondary Accession Numbers

Not Available

Cannabis Compound Identification

Common Name

Carbon dioxide

Description

Carbon dioxide, also known as [CO2] or e 290, belongs to the class of inorganic compounds known as other non-metal oxides. These are inorganic compounds containing an oxygen atom of an oxidation state of -2, in which the heaviest atom bonded to the oxygen belongs to the class of 'other non-metals'. Carbon dioxide is possibly neutral. Carbon dioxide exists in all living species, ranging from bacteria to humans. Carbon dioxide is an odorless tasting compound. Outside of the human body, Carbon dioxide has been detected, but not quantified in, several different foods, such as rowanberries, safflowers, triticales, strawberry guava, and rambutans. This could make carbon dioxide a potential biomarker for the consumption of these foods. Carbon dioxide is a potentially toxic compound. Carbon dioxide is expected to be in Cannabis as all living plants are known to produce and metabolize it.

Structure

MOL SDF PDB SMILES InChI

Synonyms

Value	Source
[CO2]	ChEBI
Carbonic anhydride	ChEBI
CO2	ChEBI
e 290	ChEBI
e-290	ChEBI
e290	ChEBI
R-744	ChEBI
Carbon oxide	HMDB
Carbon-12 dioxide	HMDB
Carbonic acid anhydride	HMDB
Carbonic acid gas	HMDB
Anhydride, carbonic	HMDB
Dioxide, carbon	HMDB

Chemical Formula

CO₂

Average Molecular Weight

44.01

Monoisotopic Molecular Weight

43.9898

IUPAC Name

methanedione

Traditional Name

carbon dioxide

CAS Registry Number

124-38-9

SMILES

O=C=O

InChI Identifier

InChI=1S/CO2/c2-1-3

InChI Key

CURLTUGMZLYLDI-UHFFFAOYSA-N

Chemical Taxonomy

Description

Belongs to the class of inorganic compounds known as other non-metal oxides. These are inorganic compounds containing an oxygen atom of an oxidation state of -2, in which the heaviest atom bonded to the oxygen belongs to the class of 'other non-metals'.

Kingdom

Inorganic compounds

Super Class

Homogeneous non-metal compounds

Class

Other non-metal organides

Sub Class

Other non-metal oxides

Direct Parent

Other non-metal oxides

Alternative Parents

Inorganic oxides

Substituents

Other non-metal oxide
Inorganic oxide

Molecular Framework

Not Available

External Descriptors

one-carbon compound (CHEBI:16526 )
carbon oxide (CHEBI:16526 )
a small molecule (CARBON-DIOXIDE )

Ontology

Physiological effect

Health effect:

Health condition:

Nervous system disorders:

Headache

Ingestion

Source:

Biological:

Animal

Plant:

Biological location:

Organ and components:

Biofluid and excreta:

Subcellular:

Cell and elements:

Extracellular

Role

Environmental role:

Greenhouse gas

Industrial application:

Pharmaceutical industry:

Biological role:

Molecular messenger:

Signaling molecule

Physical Properties

State

Liquid

Experimental Properties

Property	Value	Reference
Melting Point	-56.5 °C	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	1.48 mg/mL at 25 °C	Not Available
logP	0.83	HANSCH,C ET AL. (1995)

Predicted Properties

Property	Value	Source
logP	-0.63	ALOGPS
logP	-0.28	ChemAxon
logS	0.63	ALOGPS
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	2	ChemAxon
Hydrogen Donor Count	0	ChemAxon
Polar Surface Area	34.14 Å²	ChemAxon
Rotatable Bond Count	0	ChemAxon
Refractivity	6.38 m³·mol⁻¹	ChemAxon
Polarizability	2.57 Å³	ChemAxon
Number of Rings	0	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	Yes	ChemAxon
MDDR-like Rule	No	ChemAxon

Spectra

EI-MS/GC-MS

Type	Description	Splash Key	View
EI-MS	Mass Spectrum (Electron Ionization)	splash10-0006-9000000000-e1cf88df1066f206d01f	2014-09-20	View Spectrum
GC-MS	Carbon dioxide, non-derivatized, GC-MS Spectrum	splash10-0006-9000000000-ffb540455919d1e43969	Spectrum
GC-MS	Carbon dioxide, non-derivatized, GC-MS Spectrum	splash10-0006-9000000000-ffb540455919d1e43969	Spectrum
Predicted GC-MS	Carbon dioxide, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive	splash10-0006-9000000000-9afc44eaa1fe34c4f458	Spectrum
Predicted GC-MS	Carbon dioxide, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Carbon dioxide, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum

MS/MS

Type	Description	Splash Key	View
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 10V, Positive	splash10-0006-9000000000-eb2207f7400e9144fff7	2015-05-26	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 20V, Positive	splash10-0006-9000000000-eb2207f7400e9144fff7	2015-05-26	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 40V, Positive	splash10-0006-9000000000-eb2207f7400e9144fff7	2015-05-26	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 10V, Negative	splash10-0006-9000000000-b7e6c1e22f1f90c5a8e0	2015-05-27	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 20V, Negative	splash10-0006-9000000000-b7e6c1e22f1f90c5a8e0	2015-05-27	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 40V, Negative	splash10-0006-9000000000-b7e6c1e22f1f90c5a8e0	2015-05-27	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 10V, Positive	splash10-0006-9000000000-a1e091bb1f5fa6e9cbc7	2021-09-24	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 20V, Positive	splash10-0006-9000000000-a1e091bb1f5fa6e9cbc7	2021-09-24	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 40V, Positive	splash10-0006-9000000000-a1e091bb1f5fa6e9cbc7	2021-09-24	View Spectrum

NMR

Type	Description		View

Pathways

Name	SMPDB/Pathwhiz	KEGG
Glycine and Serine Metabolism
Ketone Body Metabolism
Histidine Metabolism
Methionine Metabolism
Ammonia Recycling

Protein Targets

Enzymes

Protein Name	Gene Name	Locus	Uniprot ID	Details
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial	PDHB	3p21.1-p14.2	P11177	details
Malonyl-CoA decarboxylase, mitochondrial	MLYCD	16q24	O95822	details
5-aminolevulinate synthase, erythroid-specific, mitochondrial	ALAS2	Xp11.21	P22557	details
5-aminolevulinate synthase, nonspecific, mitochondrial	ALAS1	3p21.1	P13196	details
Fatty acid synthase	FASN	17q25	P49327	details
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial	PDHA1	Xp22.1	P08559	details
Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial	PDHA2	4q22-q23	P29803	details
Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial	ALDH6A1	14q24.3	Q02252	details
Dihydrolipoyl dehydrogenase, mitochondrial	DLD	7q31-q32	P09622	details
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial	DLAT	11q23.1	P10515	details
Tyrosinase	TYR	11q14-q21	P14679	details
Glutaryl-CoA dehydrogenase, mitochondrial	GCDH	19p13.2	Q92947	details
Lysosomal acid lipase/cholesteryl ester hydrolase	LIPA	10q23.2-q23.3	P38571	details
Uroporphyrinogen decarboxylase	UROD	1p34	P06132	details
Coproporphyrinogen-III oxidase, mitochondrial	CPOX	3q12	P36551	details
2-amino-3-carboxymuconate-6-semialdehyde decarboxylase	ACMSD	2q21.3	Q8TDX5	details
Methylsterol monooxygenase 1	MSMO1	4q32-q34	Q15800	details
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating	NSDHL	Xq28	Q15738	details
Phytanoyl-CoA dioxygenase, peroxisomal	PHYH	10p13	O14832	details
Aromatic-L-amino-acid decarboxylase	DDC	7p12.2	P20711	details
Peroxiredoxin-6	PRDX6	1q25.1	P30041	details
2-oxoisovalerate dehydrogenase subunit beta, mitochondrial	BCKDHB	6q14.1	P21953	details
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial	BCKDHA	19q13.1-q13.2	P12694	details
Prolyl 4-hydroxylase subunit alpha-2	P4HA2	5q31	O15460	details
Prolyl 4-hydroxylase subunit alpha-1	P4HA1	10q21.3-q23.1	P13674	details
Nicotinate-nucleotide pyrophosphorylase [carboxylating]	QPRT	16p11.2	Q15274	details
Carbamoyl-phosphate synthase [ammonia], mitochondrial	CPS1	2q35	P31327	details
Gamma-butyrobetaine dioxygenase	BBOX1	11p14.2	O75936	details
S-adenosylmethionine decarboxylase proenzyme	AMD1	6q21	P17707	details
2-oxoglutarate dehydrogenase, mitochondrial	OGDH	7p14-p13	Q02218	details
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1	PLOD1	1p36.22	Q02809	details
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2	PLOD2	3q24	O00469	details
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3	PLOD3	7q22	O60568	details
Liver carboxylesterase 1	CES1	16q22.2	P23141	details
Cocaine esterase	CES2	16q22.1	O00748	details
Beta-ureidopropionase	UPB1	22q11.2	Q9UBR1	details
Aminomethyltransferase, mitochondrial	AMT	3p21.2-p21.1	P48728	details
Glutamate decarboxylase 2	GAD2	10p11.23	Q05329	details
Glutamate decarboxylase 1	GAD1	2q31	Q99259	details
Gamma-glutamyltranspeptidase 1	GGT1	22q11.23	P19440	details
Pyruvate kinase isozymes M1/M2	PKM	15q22	P14618	details
Pyruvate kinase isozymes R/L	PKLR	1q21	P30613	details
Glycine dehydrogenase [decarboxylating], mitochondrial	GLDC	9p22	P23378	details
4-hydroxyphenylpyruvate dioxygenase	HPD	12q24-qter	P32754	details
3-keto-steroid reductase	HSD17B7	1q23	P56937	details
Histidine decarboxylase	HDC	15q21-q22	P19113	details
Serine palmitoyltransferase 1	SPTLC1	9q22.2	O15269	details
Serine palmitoyltransferase 2	SPTLC2	14q24.3	O15270	details
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial	PCK2	14q11.2	Q16822	details
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]	PCK1	20q13.31	P35558	details
Multifunctional protein ADE2	PAICS	4q12	P22234	details
Isocitrate dehydrogenase [NADP], mitochondrial	IDH2	15q26.1	P48735	details
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial	IDH3B	20p13	O43837	details
Isocitrate dehydrogenase [NADP] cytoplasmic	IDH1	2q33.3	O75874	details
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial	IDH3A	15q25.1-q25.2	P50213	details
Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial	IDH3G	Xq28	P51553	details
Cysteine sulfinic acid decarboxylase	CSAD	12q13.11-q14.3	Q9Y600	details
Cytosolic 10-formyltetrahydrofolate dehydrogenase	ALDH1L1	3q21.3	O75891	details
Diphosphomevalonate decarboxylase	MVD	16q24.3	P53602	details
Aspartyl/asparaginyl beta-hydroxylase	ASPH	8q12.1	Q12797	details
Ornithine decarboxylase	ODC1	2p25	P11926	details
6-phosphogluconate dehydrogenase, decarboxylating	PGD	1p36.22	P52209	details
Uridine 5'-monophosphate synthase	UMPS	3q13	P11172	details
Vitamin K-dependent gamma-carboxylase	GGCX	2p12	P38435	details
Carbonic anhydrase 1	CA1	8q21.2	P00915	details
Carbonic anhydrase 2	CA2	8q22	P00918	details
Arginine decarboxylase	ADC	1p35.1	Q96A70	details
Phosphatidylserine decarboxylase proenzyme	PISD	22q12.2	Q9UG56	details
Carbonic anhydrase 5A, mitochondrial	CA5A	16q24.3	P35218	details
Carbonic anhydrase 3	CA3	8q21.2	P07451	details
Carbonic anhydrase 5B, mitochondrial	CA5B	Xp21.1	Q9Y2D0	details
Glycine cleavage system H protein, mitochondrial	GCSH		P23434	details
Carbonic anhydrase 12	CA12	15q22	O43570	details
Phosphopantothenoylcysteine decarboxylase	PPCDC	15q24.2	Q96CD2	details
Carbonic anhydrase 4	CA4	17q23	P22748	details
UDP-glucuronic acid decarboxylase 1	UXS1	2q12.2	Q8NBZ7	details
Carbonic anhydrase 9	CA9	9p13.3	Q16790	details
Carbonic anhydrase 13	CA13	8q21.2	Q8N1Q1	details
Trimethyllysine dioxygenase, mitochondrial	TMLHE	Xq28	Q9NVH6	details
Elongation of very long chain fatty acids protein 4	ELOVL4	6q14	Q9GZR5	details
Carbonic anhydrase 14	CA14	1q21	Q9ULX7	details
Carbonic anhydrase 7	CA7	16q22.1	P43166	details
Mitochondrial 10-formyltetrahydrofolate dehydrogenase	ALDH1L2	12q23.3	Q3SY69	details
Gamma-glutamyltransferase 6	GGT6	17p13.2	Q6P531	details
Putative uncharacterized protein PGD	PGD	1p36.3-p36.13	A9Z1X1	details
Serine palmitoyltransferase 3	SPTLC3	20p12.1	Q9NUV7	details
2-oxoglutarate dehydrogenase-like, mitochondrial	OGDHL		Q9ULD0	details
Prolyl 4-hydroxylase subunit alpha-3	P4HA3	11q13.4	Q7Z4N8	details
Lysine-specific demethylase 2A	KDM2A	11q13.2	Q9Y2K7	details
Lysine-specific demethylase 2B	KDM2B	12q24.31	Q8NHM5	details
3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial	OXSM	3p24.2	Q9NWU1	details
GGT7 protein	GGT7	20q11.22	A0PJJ9	details
Gamma-glutamyltransferase 5	GGT5	22q11.23	P36269	details
Carbonic anhydrase 6	CA6	1p36.2	P23280	details
Carboxylesterase 5A	CES5A	16q12.2	Q6NT32	details
D-dopachrome decarboxylase	DDT	22q11.23	P30046	details
Carbonic anhydrase-related protein	CA8		P35219	details

Transporters

Protein Name	Gene Name	Locus	Uniprot ID	Details
Fatty acid synthase	FASN	17q25	P49327	details
Cytosolic 10-formyltetrahydrofolate dehydrogenase	ALDH1L1	3q21.3	O75891	details
Mitochondrial 10-formyltetrahydrofolate dehydrogenase	ALDH1L2	12q23.3	Q3SY69	details

Metal Bindings

Protein Name	Gene Name	Locus	Uniprot ID	Details
Fatty acid synthase	FASN	17q25	P49327	details
2-amino-3-carboxymuconate-6-semialdehyde decarboxylase	ACMSD	2q21.3	Q8TDX5	details
Methylsterol monooxygenase 1	MSMO1	4q32-q34	Q15800	details
Phytanoyl-CoA dioxygenase, peroxisomal	PHYH	10p13	O14832	details
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial	BCKDHA	19q13.1-q13.2	P12694	details
Prolyl 4-hydroxylase subunit alpha-2	P4HA2	5q31	O15460	details
Prolyl 4-hydroxylase subunit alpha-1	P4HA1	10q21.3-q23.1	P13674	details
Gamma-butyrobetaine dioxygenase	BBOX1	11p14.2	O75936	details
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1	PLOD1	1p36.22	Q02809	details
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2	PLOD2	3q24	O00469	details
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3	PLOD3	7q22	O60568	details
Beta-ureidopropionase	UPB1	22q11.2	Q9UBR1	details
Pyruvate kinase isozymes M1/M2	PKM	15q22	P14618	details
Pyruvate kinase isozymes R/L	PKLR	1q21	P30613	details
4-hydroxyphenylpyruvate dioxygenase	HPD	12q24-qter	P32754	details
NADP-dependent malic enzyme	ME1	6q12	P48163	details
NADP-dependent malic enzyme, mitochondrial	ME3	11cen-q22.3	Q16798	details
NAD-dependent malic enzyme, mitochondrial	ME2	18q21	P23368	details
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial	PCK2	14q11.2	Q16822	details
Isocitrate dehydrogenase [NADP], mitochondrial	IDH2	15q26.1	P48735	details
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial	IDH3B	20p13	O43837	details
Isocitrate dehydrogenase [NADP] cytoplasmic	IDH1	2q33.3	O75874	details
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial	IDH3A	15q25.1-q25.2	P50213	details
Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial	IDH3G	Xq28	P51553	details
Carbonic anhydrase 1	CA1	8q21.2	P00915	details
Carbonic anhydrase 2	CA2	8q22	P00918	details
Carbonic anhydrase 5A, mitochondrial	CA5A	16q24.3	P35218	details
Carbonic anhydrase 3	CA3	8q21.2	P07451	details
Carbonic anhydrase 5B, mitochondrial	CA5B	Xp21.1	Q9Y2D0	details
Carbonic anhydrase 12	CA12	15q22	O43570	details
Carbonic anhydrase 4	CA4	17q23	P22748	details
Carbonic anhydrase 9	CA9	9p13.3	Q16790	details
Carbonic anhydrase 13	CA13	8q21.2	Q8N1Q1	details
Trimethyllysine dioxygenase, mitochondrial	TMLHE	Xq28	Q9NVH6	details
Carbonic anhydrase 14	CA14	1q21	Q9ULX7	details
Carbonic anhydrase 7	CA7	16q22.1	P43166	details
Prolyl 4-hydroxylase subunit alpha-3	P4HA3	11q13.4	Q7Z4N8	details
Lysine-specific demethylase 2A	KDM2A	11q13.2	Q9Y2K7	details
Lysine-specific demethylase 2B	KDM2B	12q24.31	Q8NHM5	details
Carbonic anhydrase 6	CA6	1p36.2	P23280	details
Carbonic anhydrase-related protein	CA8		P35219	details

Receptors

Protein Name	Gene Name	Locus	Uniprot ID	Details
Elongation of very long chain fatty acids protein 4	ELOVL4	6q14	Q9GZR5	details

Transcriptional Factors

Protein Name	Gene Name	Locus	Uniprot ID	Details
Aspartyl/asparaginyl beta-hydroxylase	ASPH	8q12.1	Q12797	details
Hypoxia-inducible factor 1-alpha inhibitor	HIF1AN	10q24	Q9NWT6	details
Carbonic anhydrase 9	CA9	9p13.3	Q16790	details
Lysine-specific demethylase 2A	KDM2A	11q13.2	Q9Y2K7	details
Lysine-specific demethylase 2B	KDM2B	12q24.31	Q8NHM5	details

Concentrations Data

Not Available

External Links

HMDB ID

HMDB0001967

DrugBank ID

DB09157

Phenol Explorer Compound ID

Not Available

FoodDB ID

FDB014084

KNApSAcK ID

Not Available

Chemspider ID

KEGG Compound ID

BioCyc ID

BiGG ID

Wikipedia Link

METLIN ID

PubChem Compound

PDB ID

Not Available

ChEBI ID

16526

References

General References

Not Available

Only showing the first 10 proteins. There are 147 proteins in total.

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Enzymes

Enzyme Details

1. Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

General function:: Involved in catalytic activity
Specific function:: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
Gene Name:: PDHB
Uniprot ID:: P11177
Molecular weight:: 39233.1

Enzyme Details

2. Malonyl-CoA decarboxylase, mitochondrial

General function:: Involved in malonyl-CoA decarboxylase activity
Specific function:: Catalyzes the conversion of malonyl-CoA to acetyl-CoA. In the fatty acid biosynthesis MCD selectively removes malonyl-CoA and thus assures that methyl-malonyl-CoA is the only chain elongating substrate for fatty acid synthase and that fatty acids with multiple methyl side chains are produced. In peroxisomes it may be involved in degrading intraperoxisomal malonyl-CoA, which is generated by the peroxisomal beta-oxidation of odd chain-length dicarboxylic fatty acids.
Gene Name:: MLYCD
Uniprot ID:: O95822
Molecular weight:: 55002.94

Enzyme Details

3. 5-aminolevulinate synthase, erythroid-specific, mitochondrial

General function:: Involved in 5-aminolevulinate synthase activity
Specific function:: Not Available
Gene Name:: ALAS2
Uniprot ID:: P22557
Molecular weight:: 64632.86

Enzyme Details

4. 5-aminolevulinate synthase, nonspecific, mitochondrial

General function:: Involved in 5-aminolevulinate synthase activity
Specific function:: Not Available
Gene Name:: ALAS1
Uniprot ID:: P13196
Molecular weight:: 70580.325

Enzyme Details

5. Fatty acid synthase

General function:: Involved in transferase activity
Specific function:: Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein.
Gene Name:: FASN
Uniprot ID:: P49327
Molecular weight:: 273424.06

Enzyme Details

6. Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

General function:: Involved in oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Specific function:: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
Gene Name:: PDHA1
Uniprot ID:: P08559
Molecular weight:: 43295.255

Enzyme Details

7. Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial

General function:: Involved in oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Specific function:: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
Gene Name:: PDHA2
Uniprot ID:: P29803
Molecular weight:: 42932.855

Enzyme Details

8. Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial

General function:: Involved in oxidoreductase activity
Specific function:: Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.
Gene Name:: ALDH6A1
Uniprot ID:: Q02252
Molecular weight:: 57839.31

Enzyme Details

9. Dihydrolipoyl dehydrogenase, mitochondrial

General function:: Involved in oxidoreductase activity
Specific function:: Lipoamide dehydrogenase is a component of the glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes. Involved in the hyperactivation of spermatazoa during capacitation and in the spermatazoal acrosome reaction.
Gene Name:: DLD
Uniprot ID:: P09622
Molecular weight:: 54176.91

Enzyme Details

10. Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

General function:: Involved in acyltransferase activity
Specific function:: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
Gene Name:: DLAT
Uniprot ID:: P10515
Molecular weight:: 68996.03

Transporters

Enzyme Details

1. Fatty acid synthase

General function:: Involved in transferase activity
Specific function:: Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein.
Gene Name:: FASN
Uniprot ID:: P49327
Molecular weight:: 273424.06

Enzyme Details

2. Cytosolic 10-formyltetrahydrofolate dehydrogenase

General function:: Involved in formyltetrahydrofolate dehydrogenase activity
Specific function:: Not Available
Gene Name:: ALDH1L1
Uniprot ID:: O75891
Molecular weight:: 99752.535

Enzyme Details

3. Mitochondrial 10-formyltetrahydrofolate dehydrogenase

General function:: Involved in formyltetrahydrofolate dehydrogenase activity
Specific function:: Not Available
Gene Name:: ALDH1L2
Uniprot ID:: Q3SY69
Molecular weight:: 101744.98

Only showing the first 10 proteins. There are 147 proteins in total.

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Showing Compound Card for Carbon dioxide (CDB004931)

Structure for CDB004931 (Carbon dioxide)

Enzymes

Transporters