| Identification |
|---|
| HMDB Protein ID
| CDBP04609 |
| Secondary Accession Numbers
| Not Available |
| Name
| Carboxylesterase 5A |
| Description
| Not Available |
| Synonyms
|
- Carboxylesterase-like urinary excreted protein homolog
- Cauxin
|
| Gene Name
| CES5A |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Lipid transport and metabolism |
| Specific Function
| Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs (By similarity).
|
| GO Classification
|
| Cellular Component |
| extracellular region |
| Molecular Function |
| carboxylesterase activity |
| retinyl-palmitate esterase activity |
| methyl indole-3-acetate esterase activity |
| methyl jasmonate esterase activity |
| methyl salicylate esterase activity |
|
| Cellular Location
|
- Secreted
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 16 |
| Locus
| 16q12.2 |
| SNPs
| CES7 |
| Gene Sequence
|
>1728 bp
ATGAGTGGGAATTGGGTGCACCCAGGCCAGATCCTAATTTGGGCTATCTGGGTCCTTGCA
GCCCCCACCAAAGGGCCTTCTGCTGAAGGGCCACAGAGGAACACCAGGCTGGGATGGATT
CAGGGCAAGCAAGTCACTGTGCTGGGAAGCCCTGTGCCTGTGAACGTGTTCCTCGGAGTC
CCCTTTGCTGCTCCCCCGCTGGGATCCCTGCGATTTACGAACCCGCAGCCTGCATCGCCC
TGGGATAACTTGCGAGAAGCCACCTCCTACCCTAATTTGTGCCTCCAGAACTCAGAGTGG
CTGCTCTTAGATCAACATATGCTCAAGGTGCATTACCCGAAATTCGGAGTGTCAGAAGAC
TGCCTCTACCTGAACATCTATGCGCCTGCCCACGCCGATACAGGCTCCAAGCTCCCCGTC
TTGGTGTGGTTCCCAGGAGGTGCCTTCAAGACTGGCTCAGCCTCCATCTTTGATGGGTCC
GCCCTGGCTGCCTATGAGGACGTGCTGGTTGTGGTCGTCCAGTACCGGCTAGGAATATTT
GGTTTCTTCACCACATGGGATCAGCATGCTCCGGGGAACTGGGCCTTCAAGGACCAGGTG
GCTGCTCTGTCCTGGGTCCAGAAGAACATCGAGTTCTTCGGTGGGGACCCCAGCTCTGTG
ACCATCTTTGGCGAGTCCGCGGGAGCCATAAGTGTTTCTAGTCTTATACTGTCTCCCATG
GCCAAAGGCTTATTCCACAAAGCCATCATGGAGAGTGGGGTGGCCATCATCCCTTACCTG
GAGGCCCATGATTATGAGAAGAGTGAGGACCTGCAGGTGGTTGCACATTTCTGTGGTAAC
AATGCGTCAGACTCTGAGGCCCTGCTGAGGTGCCTGAGGACAAAACCCTCCAAGGAGCTG
CTGACCCTCAGCCAGAAAACAAAGTCTTTCACTCGAGTGGTTGATGGTGCTTTCTTTCCT
AATGAGCCTCTAGATCTATTGTCTCAGAAAGCATTTAAAGCAATTCCTTCCATCATCGGA
GTCAATAACCACGAGTGTGGCTTCCTGCTGCCTATGAAGGAGGCTCCTGAGATCCTCAGT
GGCTCCAACAAGTCCCTTGCCCTCCATCTGATACAAAACATCCTGCACATCCCGCCTCAG
TATTTGCACCTTGTGGCTAATGAATACTTCCATGACAAGCACTCCCTGACTGAAATCCGA
GACAGTCTTCTGGACTTGCTTGGAGATGTGTTCTTTGTGGTCCCTGCACTGATCACAGCT
CGATATCACAGAGATGCTGGTGCACCTGTCTACTTCTATGAGTTTCGGCACCGGCCTCAG
TGCTTTGAAGACACGAAGCCAGCTTTTGTCAAAGCCGACCACGCTGATGAAGTCCGCTTT
GTGTTCGGTGGTGCCTTCCTGAAGGGGGACATTGTTATGTTCGAAGGAGCCACGGAGGAG
GAGAAGTTACTGAGCCGGAAGATGATGAAATACTGGGCTACCTTTGCTCGAACCGGGAAT
CCTAATGGGAACGACCTGTCTCTGTGGCCAGCTTATAATCTGACTGAGCAGTACCTCCAG
CTGGACTTGAACATGAGCCTCGGACAGAGACTCAAAGAACCGCGGGTGGATTTTTGGACC
AGCACCATCCCCCTGATCCTGTCTGCCTCCGACATGCTCCACAGTCCTCTTTCTTCCTTA
ACTTTCCTCTCTCTCCTCCAGCCTTTCTTTTTCTTTTGTGCTCCTTGA
|
| Protein Properties |
|---|
| Number of Residues
| 575 |
| Molecular Weight
| 63925.82 |
| Theoretical pI
| 6.442 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Carboxylesterase 7
MSGNWVHPGQILIWAIWVLAAPTKGPSAEGPQRNTRLGWIQGKQVTVLGSPVPVNVFLGV
PFAAPPLGSLRFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKFGVSED
CLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIF
GFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPM
AKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPSKEL
LTLSQKTKSFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILS
GSNKSLALHLIQNILHIPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVPALITA
RYHRDAGAPVYFYEFRHRPQCFEDTKPAFVKADHADEVRFVFGGAFLKGDIVMFEGATEE
EKLLSRKMMKYWATFARTGNPNGNDLSLWPAYNLTEQYLQLDLNMSLGQRLKEPRVDFWT
STIPLILSASDMLHSPLSSLTFLSLLQPFFFFCAP
|
| External Links |
|---|
| GenBank ID Protein
| 219521907 |
| UniProtKB/Swiss-Prot ID
| Q6NT32 |
| UniProtKB/Swiss-Prot Entry Name
| EST7_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_001143685.1 |
| GeneCard ID
| CES7 |
| GenAtlas ID
| CES7 |
| HGNC ID
| HGNC:26459 |
| References |
|---|
| General References
| Not Available |