| Identification |
|---|
| HMDB Protein ID
| CDBP04601 |
| Secondary Accession Numbers
| Not Available |
| Name
| Carbonic anhydrase 6 |
| Description
| Not Available |
| Synonyms
|
- CA-VI
- Carbonate dehydratase VI
- Carbonic anhydrase VI
- Salivary carbonic anhydrase
- Secreted carbonic anhydrase
|
| Gene Name
| CA6 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in carbonate dehydratase activity |
| Specific Function
| Reversible hydration of carbon dioxide. Its role in saliva is unknown.
|
| GO Classification
|
| Biological Process |
| small molecule metabolic process |
| bicarbonate transport |
| one-carbon metabolic process |
| Cellular Component |
| cytoplasm |
| extracellular region |
| extracellular space |
| Component |
| extracellular region |
| Function |
| binding |
| catalytic activity |
| carbonate dehydratase activity |
| transition metal ion binding |
| zinc ion binding |
| lyase activity |
| carbon-oxygen lyase activity |
| hydro-lyase activity |
| ion binding |
| cation binding |
| metal ion binding |
| Molecular Function |
| metal ion binding |
| zinc ion binding |
| carbonate dehydratase activity |
| Process |
| metabolic process |
| cellular metabolic process |
| one-carbon metabolic process |
|
| Cellular Location
|
- Secreted
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 1 |
| Locus
| 1p36.2 |
| SNPs
| CA6 |
| Gene Sequence
|
>927 bp
ATGAGGGCCCTGGTGCTTCTGCTGTCCCTGTTCCTGCTGGGTGGCCAGGCCCAGCATGTG
TCTGACTGGACCTACTCAGAAGGGGCACTGGACGAAGCGCACTGGCCACAGCACTACCCC
GCCTGTGGGGGCCAGAGACAGTCGCCTATCAACCTACAGAGGACGAAGGTGCGGTACAAC
CCCTCCTTGAAGGGGCTCAATATGACAGGCTATGAGACCCAGGCAGGGGAGTTCCCCATG
GTCAACAATGGCCACACAGTGCAGATCGGCCTGCCCTCCACCATGCGCATGACAGTGGCT
GACGGCATTGTATACATAGCCCAGCAGATGCACTTTCACTGGGGAGGTGCGTCCTCGGAG
ATCAGCGGCTCTGAGCACACCGTGGACGGGATCAGACATGTGATCGAGATTCACATTGTT
CACTACAATTCTAAATACAAGACGTATGATATAGCCCAAGATGCGCCGGATGGTTTGGCT
GTACTGGCAGCCTTCGTTGAGGTGAAGAATTACCCTGAAAACACTTATTACAGCAACTTC
ATTTCTCATCTGGCCAACATCAAGTACCCAGGACAAAGAACAACCCTGACTGGCCTTGAC
GTTCAGGACATGCTGCCCAGGAACCTCCAGCACTACTACACCTACCATGGCTCACTCACC
ACGCCTCCCTGCACTGAGAACGTCCACTGGTTTGTGCTGGCAGATTTTGTCAAGCTCTCC
AGGACACAGGTTTGGAAGCTGGAGAATTCCTTACTGGATCACCGCAACAAGACCATCCAC
AACGATTACCGCAGGACCCAGCCCCTGAAACACAGAGTGGTGGAATCCAACTTCCCGAAT
CAGGAATACACTCTAGGCTCTGAATTCCAGTTTTACCTACATAAGATTGAGGAAATTCTT
GACTACTTAAGAAGAGCATTGAACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 308 |
| Molecular Weight
| 35366.615 |
| Theoretical pI
| 7.027 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Carbonic anhydrase 6
MRALVLLLSLFLLGGQAQHVSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYN
PSLKGLNMTGYETQAGEFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSE
ISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNF
ISHLANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLS
RTQVWKLENSLLDHRNKTIHNDYRRTQPLNHRVVESNFPNQEYTLGSEFQFYLHKIEEIL
DYLRRALN
|
| External Links |
|---|
| GenBank ID Protein
| 179732 |
| UniProtKB/Swiss-Prot ID
| P23280 |
| UniProtKB/Swiss-Prot Entry Name
| CAH6_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| M57892 |
| GeneCard ID
| CA6 |
| GenAtlas ID
| CA6 |
| HGNC ID
| HGNC:1380 |
| References |
|---|
| General References
| Not Available |