Cannabis Compound Database: Showing Protein Nicotinate-nucleotide pyrophosphorylase [carboxylating] (CDBP00331)

Identification Biological properties Gene properties Protein properties External links References XML Show 6 compounds

Identification

HMDB Protein ID

CDBP00331

Secondary Accession Numbers

Not Available

Name

Nicotinate-nucleotide pyrophosphorylase [carboxylating]

Description

Not Available

Synonyms

QAPRTase
QPRTase
Quinolinate phosphoribosyltransferase [decarboxylating]

Gene Name

QPRT

Protein Type

Enzyme

Biological Properties

General Function

Involved in catalytic activity

Specific Function

Involved in the catabolism of quinolinic acid (QA).

GO Classification

Biological Process
NAD biosynthetic process
quinolinate catabolic process
protein oligomerization
water-soluble vitamin metabolic process
NAD metabolic process
Cellular Component
cytosol
Function
transferase activity
transferase activity, transferring pentosyl groups
nicotinate-nucleotide diphosphorylase (carboxylating) activity
transferase activity, transferring glycosyl groups
catalytic activity
Molecular Function
nicotinate-nucleotide diphosphorylase (carboxylating) activity
protein homodimerization activity
Process
metabolic process
coenzyme biosynthetic process
pyridine nucleotide biosynthetic process
nicotinamide nucleotide biosynthetic process
nad biosynthetic process
cellular metabolic process
cofactor metabolic process
coenzyme metabolic process

Cellular Location

Not Available

Pathways

Name	SMPDB/Pathwhiz	KEGG
Nicotinate and Nicotinamide Metabolism
NAD(+) biosynthesis	Not Available	Not Available

Gene Properties

Chromosome Location

Locus

16p11.2

SNPs

QPRT

Gene Sequence

>894 bp
ATGGACGCTGAAGGCCTGGCGCTGCTGCTGCCGCCCGTCACCCTGGCAGCCCTGGTGGAC
AGCTGGCTCCGAGAGGACTGCCCAGGGCTCAACTACGCAGCCTTGGTCAGCGGGGCAGGC
CCCTCGCAGGCGGCGCTGTGGGCCAAATCCCCTGGGATACTGGCAGGGCAGCCTTTCTTC
GATGCCATATTTACCCAACTCAACTGCCAAGTCTCCTGGTTCCTCCCCGAGGGATCGAAG
CTGGTGCCGGTGGCCAGAGTGGCCGAGGTCCGGGGCCCTGCCCACTGCCTGCTGCTGGGG
GAACGGGTGGCCCTCAACACGCTGGCCCGCTGCAGTGGCATTGCCAGTGCTGCCGCCGCT
GCAGTGGAGGCCGCCAGGGGGGCCGGCTGGACTGGGCACGTGGCAGGCACGAGGAAGACC
ACGCCAGGCTTCCGGCTGGTGGAGAAGTATGGGCTCCTGGTGGGCGGGGCCGCCTCGCAC
CGCTACGACCTGGGAGGGCTGGTGATGGTGAAGGATAACCATGTGGTGGCCGCCGGTGGC
GTGGAGAAGGCGGTGCGGGCGGCCAGACAGGCGGCTGACTTCGCTCTGAAGGTGGAAGTG
GAATGCAGCAGCCTGCAGGAGGCCGTGCAGGCAGCTGAGGCTGGTGCCGACCTTGTCCTG
CTGGACAACTTCAAGCCAGAGGAGCTGCACCCCACGGCCACCGTGCTGAAGGCCCAGTTC
CCGAGTGTGGCTGTGGAAGCCAGTGGGGGCATCACCCTGGACAACCTCCCCCAGTTCTGC
GGGCCGCACATAGACGTCATCTCCATGGGGATGCTGACCCAGGCGGCCCCAGCCCTTGAT
TTCTCCCTCAAGCTGTTTGCCAAAGAGGTGGCTCCAGTGCCCAAAATCCACTAG

Protein Properties

Number of Residues

297

Molecular Weight

30815.28

Theoretical pI

6.211

Pfam Domain Function

QRPTase_C (PF01729 )
QRPTase_N (PF02749 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Nicotinate-nucleotide pyrophosphorylase [carboxylating]
MDAEGLALLLPPVTLAALVDSWLREDCPGLNYAALVSGAGPSQAALWAKSPGVLAGQPFF
DAIFTQLNCQVSWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAA
AVEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGG
VEKAVRAARQAADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQF
PSVAVEASGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKLFAKEVAPVPKIH

External Links

GenBank ID Protein

13477197

UniProtKB/Swiss-Prot ID

Q15274

UniProtKB/Swiss-Prot Entry Name

NADC_HUMAN

PDB IDs