| Identification |
|---|
| HMDB Protein ID
| CDBP02252 |
| Secondary Accession Numbers
| Not Available |
| Name
| Phosphopantothenoylcysteine decarboxylase |
| Description
| Not Available |
| Synonyms
|
- CoaC
- PPC-DC
|
| Gene Name
| PPCDC |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in catalytic activity |
| Specific Function
| Necessary for the biosynthesis of coenzyme A. Catalyzes the decarboxylation of 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine.
|
| GO Classification
|
| Biological Process |
| pantothenate metabolic process |
| coenzyme A biosynthetic process |
| coenzyme biosynthetic process |
| Cellular Component |
| cytosol |
| Function |
| catalytic activity |
| Molecular Function |
| phosphopantothenoylcysteine decarboxylase activity |
|
| Cellular Location
|
Not Available
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Pantothenate and CoA Biosynthesis |    |  | | coenzyme A biosynthesis | Not Available | Not Available |
|
| Gene Properties |
|---|
| Chromosome Location
| 15 |
| Locus
| 15q24.2 |
| SNPs
| PPCDC |
| Gene Sequence
|
>615 bp
ATGGAACCAAAGGCCTCCTGTCCAGCTGCTGCACCCTTGATGGAGAGAAAATTCCATGTT
CTTGTGGGTGTCACGGGGAGTGTCGCAGCCCTGAAGTTGCCTCTTCTGGTGTCAAAGCTT
TTGGACATTCCTGGGCTGGAAGTAGCAGTGGTCACAACTGAGAGAGCCAAACATTTCTAC
AGCCCCCAGGACATTCCTGTCACCCTCTACAGCGACGCTGATGAATGGGAGATATGGAAG
AGCCGCTCTGACCCAGTTCTGCACATTGACCTGCGGAGGTGGGCAGACCTCCTGCTGGTG
GCTCCTCTTGATGCCAACACTCTGGGGAAGGTGGCCAGTGGCATCTGTGACAACTTGCTT
ACCTGCGTCATGCGGGCCTGGGACCGCAGCAAGCCCCTGCTCTTCTGCCCGGCCATGAAC
ACCGCCATGTGGGAGCACCCGATCACAGCGCAGCAGGTAGACCAGCTCAAGGCCTTTGGC
TATGTCGAGATCCCCTGTGTGGCCAAGAAGCTGGTGTGCGGAGATGAAGGTCTCGGGGCC
ATGGCTGAAGTGGGGACCATCGTGGACAAAGTGAAAGAAGTCCTCTTCCAGCACAGTGGC
TTCCAGCAGAGTTGA
|
| Protein Properties |
|---|
| Number of Residues
| 204 |
| Molecular Weight
| 22394.965 |
| Theoretical pI
| 6.102 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Phosphopantothenoylcysteine decarboxylase
MEPKASCPAAAPLMERKFHVLVGVTGSVAALKLPLLVSKLLDIPGLEVAVVTTERAKHFY
SPQDIPVTLYSDADEWEIWKSRSDPVLHIDLRRWADLLLVAPLDANTLGKVASGICDNLL
TCVMRAWDRSKPLLFCPAMNTAMWEHPITAQQVDQLKAFGYVEIPCVAKKLVCGDEGLGA
MAEVGTIVDKVKEVLFQHSGFQQS
|
| External Links |
|---|
| GenBank ID Protein
| 71725351 |
| UniProtKB/Swiss-Prot ID
| Q96CD2 |
| UniProtKB/Swiss-Prot Entry Name
| COAC_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| NM_021823.3 |
| GeneCard ID
| PPCDC |
| GenAtlas ID
| PPCDC |
| HGNC ID
| HGNC:28107 |
| References |
|---|
| General References
| Not Available |