| Identification |
| HMDB Protein ID
| CDBP01760 |
| Secondary Accession Numbers
| Not Available |
| Name
| Carbonic anhydrase 1 |
| Description
| Not Available |
| Synonyms
|
- CA-I
- CAB
- Carbonate dehydratase I
- Carbonic anhydrase B
- Carbonic anhydrase I
|
| Gene Name
| CA1 |
| Protein Type
| Enzyme |
| Biological Properties |
| General Function
| Involved in carbonate dehydratase activity |
| Specific Function
| Reversible hydration of carbon dioxide. Can hydrates cyanamide to urea.
|
| GO Classification
|
| Biological Process |
| small molecule metabolic process |
| bicarbonate transport |
| one-carbon metabolic process |
| Cellular Component |
| cytosol |
| Golgi apparatus |
| Component |
| cell part |
| intracellular part |
| cytoplasm |
| Function |
| lyase activity |
| carbon-oxygen lyase activity |
| hydro-lyase activity |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| catalytic activity |
| carbonate dehydratase activity |
| transition metal ion binding |
| zinc ion binding |
| Molecular Function |
| metal ion binding |
| zinc ion binding |
| carbonate dehydratase activity |
| Process |
| metabolic process |
| cellular metabolic process |
| one-carbon metabolic process |
|
| Cellular Location
|
- Cytoplasm
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Gastric Acid Production |    | Not Available | | Esomeprazole Action Pathway |    | Not Available | | Omeprazole Action Pathway |    | Not Available | | Lansoprazole Action Pathway |    | Not Available | | Pantoprazole Action Pathway |    | Not Available |
|
| Gene Properties |
| Chromosome Location
| 8 |
| Locus
| 8q21.2 |
| SNPs
| CA1 |
| Gene Sequence
|
>786 bp
ATGGCAAGTCCAGACTGGGGATATGATGACAAAAATGGTCCTGAACAATGGAGCAAGCTG
TATCCCATTGCCAATGGAAATAACCAATCCCCTGTTGATATTAAAACCAGTGAAACCAAA
CATGACACCTCTCTGAAACCTATTAGTGTCTCCTACAACCCAGCCACAGCCAAAGAAATT
ATCAATGTGGGGCATTCTTTCCATGTAAATTTTGAGGACAACGATAACCGATCAGTGCTG
AAAGGTGGTCCTTTCTCTGACAGCTACAGGCTCTTTCAGTTTCATTTTCACTGGGGCAGT
ACAAATGAGCATGGTTCAGAACATACAGTGGATGGAGTCAAATATTCTGCCGAGCTTCAC
GTAGCTCACTGGAATTCTGCAAAGTACTCCAGCCTTGCTGAAGCTGCCTCAAAGGCTGAT
GGTTTGGCAGTTATTGGTGTTTTGATGAAGGTTGGTGAGGCCAACCCAAAGCTGCAGAAA
GTACTTGATGCCCTCCAAGCAATTAAAACCAAGGGCAAACGAGCCCCATTCACAAATTTT
GACCCCTCTACTCTCCTTCCTTCATCCCTGGATTTCTGGACCTACCCTGGCTCTCTGACT
CATCCTCCTCTTTATGAGAGTGTAACTTGGATCATCTGTAAGGAGAGCATCAGTGTCAGC
TCAGAGCAGCTGGCACAATTCCGCAGCCTTCTATCAAATGTTGAAGGTGATAACGCTGTC
CCCATGCAGCACAACAACCGCCCAACCCAACCTCTGAAGGGCAGAACAGTGAGAGCTTCA
TTTTGA
|
| Protein Properties |
| Number of Residues
| 261 |
| Molecular Weight
| 28870.0 |
| Theoretical pI
| 7.117 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Carbonic anhydrase 1
MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEI
INVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELH
VAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNF
DPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV
PMQHNNRPTQPLKGRTVRASF
|
| External Links |
| GenBank ID Protein
| 29600 |
| UniProtKB/Swiss-Prot ID
| P00915 |
| UniProtKB/Swiss-Prot Entry Name
| CAH1_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| X05014 |
| GeneCard ID
| CA1 |
| GenAtlas ID
| CA1 |
| HGNC ID
| HGNC:1368 |
| References |
| General References
| Not Available |