Cannabis Compound Database: Showing Compound Card for 1-Hexanol (CDB000490)

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Identification Taxonomy Ontology Physical properties Spectra Protein target Pathways Concentrations Links References enzymes (31)transporters (1) Show 53 proteins XML

Record Information

Version

1.0

Created at

2020-03-19 00:39:50 UTC

Updated at

2020-12-07 19:07:28 UTC

CannabisDB ID

CDB000490

Secondary Accession Numbers

Not Available

Cannabis Compound Identification

Common Name

1-Hexanol

Description

1-Hexanol, also known as 1-hexyl alcohol or 1-hydroxyhexane, belongs to the class of organic compounds known as fatty alcohols. These are aliphatic alcohols consisting of a chain of a least six carbon atoms. 1-Hexanol is a very hydrophobic molecule, practically insoluble in water, and relatively neutral. 1-Hexanol is an organic alcohol with a six-carbon chain and a chemical formula of CH3(CH2)5OH. This colorless liquid is poorly soluble in water, but miscible with ether and ethanol. Two additional straight chain isomers of 1-hexanol exist, 2-hexanol and 3-hexanol, both of which differ by the location of the hydroxyl group. Many isomeric alcohols have the formula C6H13OH. 1-hexanol is believed to be a component of the odour of freshly mown grass. It is used in the perfume industry and as a flavouring agent. 1-Hexanol is found in many plants, some of which are lemon, tea, yellow bell pepper, and hyssop. 1-Hexanol is a common constituent of essential oils (e.g. orange-peel oil) and it has also been identified as a volatile component of Cannabis sativa (PMID: 26657499 ).

Structure

MOL SDF 3D-SDF PDB SMILES InChI View 3D Structure

Synonyms

Value	Source
1-Hexyl alcohol	ChEBI
1-Hydroxyhexane	ChEBI
Caproic alcohol	ChEBI
Hexanol	ChEBI
N-Hexyl alcohol	ChEBI
1-Hexanol, aluminum salt	MeSH
N-Hexanol	MeSH
Alcohol C-6	HMDB
Alcohol(C6)	HMDB
Amylcarbinol	HMDB
BHL	HMDB
C6 Alcohol	HMDB
Caproyl alcohol	HMDB
Cyclohexan-1-ol	HMDB
Cyclohexanol	HMDB
Epal 6	HMDB
Exxal 6	HMDB
Fatty alcohol(C6)	HMDB
HEX	HMDB
Hexahydrophenol	HMDB
Hexalin	HMDB
Hexan-1-ol	HMDB
Hexanol-(1)	HMDB
Hexanol-CMPD	HMDB
Hexyl alcohol	HMDB
Hexyl alcohol (natural)	HMDB
Hexyl alcohol, active	HMDB
N-Hexan-1-ol	HMDB
N-Hexenol	HMDB
Pentylcarbinol	HMDB
1-Hexanol	MeSH

Chemical Formula

C₆H₁₄O

Average Molecular Weight

102.17

Monoisotopic Molecular Weight

102.1045

IUPAC Name

hexan-1-ol

Traditional Name

hexanol

CAS Registry Number

111-27-3

SMILES

CCCCCCO

InChI Identifier

InChI=1S/C6H14O/c1-2-3-4-5-6-7/h7H,2-6H2,1H3

InChI Key

ZSIAUFGUXNUGDI-UHFFFAOYSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as fatty alcohols. These are aliphatic alcohols consisting of a chain of a least six carbon atoms.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Fatty Acyls

Sub Class

Fatty alcohols

Direct Parent

Fatty alcohols

Alternative Parents

Substituents

Fatty alcohol
Organic oxygen compound
Hydrocarbon derivative
Primary alcohol
Organooxygen compound
Alcohol
Aliphatic acyclic compound

Molecular Framework

Aliphatic acyclic compounds

External Descriptors

primary alcohol (CHEBI:87393 )
Fatty alcohols (LMFA05000117 )
a small molecule (HEXANOL-CMPD )

Ontology

Disposition

Route of exposure:

Enteral:

Ingestion

Source:

Biological:

Animal

Plant:

Biological location:

Biofluid and excreta:

Cell and elements:

Extracellular

Subcellular:

Role

Industrial application:

Food and nutrition:

Flavoring agent

Personal care products:

Perfuming agent

Biological role:

Physical Properties

State

Solid

Experimental Properties

Property	Value	Reference
Melting Point	-44.6 °C	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
logP	2.03	HANSCH,C ET AL. (1995)

Predicted Properties

Property	Value	Source
logP	2.03	ALOGPS
logP	1.69	ChemAxon
logS	-1.1	ALOGPS
pKa (Strongest Acidic)	16.84	ChemAxon
pKa (Strongest Basic)	-2	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	1	ChemAxon
Hydrogen Donor Count	1	ChemAxon
Polar Surface Area	20.23 Å²	ChemAxon
Rotatable Bond Count	4	ChemAxon
Refractivity	31.34 m³·mol⁻¹	ChemAxon
Polarizability	13.27 Å³	ChemAxon
Number of Rings	0	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	Yes	ChemAxon
MDDR-like Rule	No	ChemAxon

Spectra

EI-MS/GC-MS

Type	Description	Splash Key	View
EI-MS	Mass Spectrum (Electron Ionization)	splash10-052f-9000000000-26ed9611cc7f575d818b	2014-09-20	View Spectrum
GC-MS	1-Hexanol, non-derivatized, GC-MS Spectrum	splash10-0a4l-9000000000-029ae838da9e13a0e457	Spectrum
GC-MS	1-Hexanol, non-derivatized, GC-MS Spectrum	splash10-0a4l-9000000000-35926852ac4ed3ed0959	Spectrum
GC-MS	1-Hexanol, non-derivatized, GC-MS Spectrum	splash10-0a4l-9000000000-612a7e611628b904745f	Spectrum
GC-MS	1-Hexanol, non-derivatized, GC-MS Spectrum	splash10-000i-9000000000-48f5c5da7cd09948311e	Spectrum
GC-MS	1-Hexanol, non-derivatized, GC-MS Spectrum	splash10-0a4l-9000000000-df7ed15b6c10248ee93a	Spectrum
GC-MS	1-Hexanol, non-derivatized, GC-MS Spectrum	splash10-0a4l-9000000000-65cf94afbc05ce616b62	Spectrum
GC-MS	1-Hexanol, non-derivatized, GC-MS Spectrum	splash10-0a4l-9000000000-f121c161f3815adad6e6	Spectrum
GC-MS	1-Hexanol, non-derivatized, GC-MS Spectrum	splash10-052f-9000000000-003fe1ca0e7fdfcbdd97	Spectrum
GC-MS	1-Hexanol, non-derivatized, GC-MS Spectrum	splash10-0a4l-9000000000-029ae838da9e13a0e457	Spectrum
GC-MS	1-Hexanol, non-derivatized, GC-MS Spectrum	splash10-0a4l-9000000000-35926852ac4ed3ed0959	Spectrum
GC-MS	1-Hexanol, non-derivatized, GC-MS Spectrum	splash10-0a4l-9000000000-612a7e611628b904745f	Spectrum
GC-MS	1-Hexanol, non-derivatized, GC-MS Spectrum	splash10-000i-9000000000-48f5c5da7cd09948311e	Spectrum
GC-MS	1-Hexanol, non-derivatized, GC-MS Spectrum	splash10-0a4l-9000000000-df7ed15b6c10248ee93a	Spectrum
GC-MS	1-Hexanol, non-derivatized, GC-MS Spectrum	splash10-0a4l-9000000000-65cf94afbc05ce616b62	Spectrum
GC-MS	1-Hexanol, non-derivatized, GC-MS Spectrum	splash10-0a4l-9000000000-f121c161f3815adad6e6	Spectrum
GC-MS	1-Hexanol, non-derivatized, GC-MS Spectrum	splash10-052f-9000000000-003fe1ca0e7fdfcbdd97	Spectrum
Predicted GC-MS	1-Hexanol, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive	splash10-056u-9000000000-118d12981b86ce381ebd	Spectrum
Predicted GC-MS	1-Hexanol, 1 TMS, Predicted GC-MS Spectrum - 70eV, Positive	splash10-00di-9300000000-7090cf9145edfffd8de0	Spectrum
Predicted GC-MS	1-Hexanol, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum

MS/MS

Type	Description	Splash Key	View
MS/MS	LC-MS/MS Spectrum - QTOF 7V, positive	splash10-000i-9000000000-34d8cf6a0a5f99d7b239	2020-07-22	View Spectrum
MS/MS	LC-MS/MS Spectrum - QTOF 10V, positive	splash10-000l-9000000000-93a8e902c6f20d518e6e	2020-07-22	View Spectrum
MS/MS	LC-MS/MS Spectrum - QTOF 15V, positive	splash10-0006-9000000000-817448b00815a05c099f	2020-07-22	View Spectrum
MS/MS	LC-MS/MS Spectrum - QTOF 17V, positive	splash10-0006-9000000000-bb995d565d8efee48a53	2020-07-22	View Spectrum
MS/MS	LC-MS/MS Spectrum - QTOF 20V, positive	splash10-0006-9000000000-9c2e3b526514227b5954	2020-07-22	View Spectrum
MS/MS	LC-MS/MS Spectrum - QTOF 23V, positive	splash10-0006-9000000000-ddd13faf0a10185ac38f	2020-07-22	View Spectrum
MS/MS	LC-MS/MS Spectrum - QTOF 25V, positive	splash10-0006-9000000000-29d21c96ea231fc20c2f	2020-07-22	View Spectrum
MS/MS	LC-MS/MS Spectrum - QTOF 27V, positive	splash10-0006-9000000000-cb2eaacaf54e58c3408b	2020-07-22	View Spectrum
MS/MS	LC-MS/MS Spectrum - QTOF 30V, positive	splash10-0006-9000000000-af41c3ef4b594956cc94	2020-07-22	View Spectrum
MS/MS	LC-MS/MS Spectrum - QTOF 33V, positive	splash10-0006-9000000000-88cf8122694ad634e9ba	2020-07-22	View Spectrum
MS/MS	LC-MS/MS Spectrum - QTOF 35V, positive	splash10-0006-9000000000-05a459922ab22eb5a749	2020-07-22	View Spectrum
MS/MS	LC-MS/MS Spectrum - QTOF 3V, positive	splash10-0006-9000000000-4dfbfb07af734375bb20	2020-07-22	View Spectrum
MS/MS	LC-MS/MS Spectrum - QTOF 4V, positive	splash10-0006-9000000000-67f1d2fb3dcd71e1f02c	2020-07-22	View Spectrum
MS/MS	LC-MS/MS Spectrum - QTOF 5V, positive	splash10-0006-9000000000-ac4cc1d63a02856aae86	2020-07-22	View Spectrum
MS/MS	LC-MS/MS Spectrum - QTOF 7V, positive	splash10-0006-9000000000-ad4885a4e0e7c3ce30d1	2020-07-22	View Spectrum
MS/MS	LC-MS/MS Spectrum - QTOF 10V, positive	splash10-0006-9000000000-46264fd40c3ba6acb30e	2020-07-22	View Spectrum
MS/MS	LC-MS/MS Spectrum - QTOF 15V, positive	splash10-0006-9000000000-db820e796357d6b2dd1e	2020-07-22	View Spectrum
MS/MS	LC-MS/MS Spectrum - QTOF 17V, positive	splash10-0006-9000000000-695b77a970e008201389	2020-07-22	View Spectrum
MS/MS	LC-MS/MS Spectrum - QTOF 20V, positive	splash10-0006-9000000000-8b4cec3d369d30b0fe83	2020-07-22	View Spectrum
MS/MS	LC-MS/MS Spectrum - QTOF 23V, positive	splash10-0006-9000000000-00882c5a71f3ac89f872	2020-07-22	View Spectrum
MS/MS	LC-MS/MS Spectrum - QTOF 25V, positive	splash10-0006-9000000000-df3f313f6cf901b9b25b	2020-07-22	View Spectrum
MS/MS	LC-MS/MS Spectrum - QTOF 27V, positive	splash10-0006-9000000000-ea330b0bdd832ab426cf	2020-07-22	View Spectrum
MS/MS	LC-MS/MS Spectrum - QTOF 30V, positive	splash10-0006-9000000000-42749ebd8ebeaa0ebb5c	2020-07-22	View Spectrum
MS/MS	LC-MS/MS Spectrum - QTOF 33V, positive	splash10-000f-9000000000-1ff1f3558a9db25d0067	2020-07-22	View Spectrum
MS/MS	LC-MS/MS Spectrum - QTOF 35V, positive	splash10-000f-9000000000-6ac31d169cdb4a253db7	2020-07-22	View Spectrum

NMR

Type	Description	View
1D NMR	¹H NMR Spectrum (1D, 90 MHz, CDCl₃, experimental)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 25.16 MHz, CDCl₃, experimental)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 100 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 1000 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 200 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 300 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 400 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 500 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 600 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 700 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 800 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 900 MHz, D₂O, predicted)	Spectrum

Pathways

Not Available

Protein Targets

Enzymes

Protein Name	Gene Name	Locus	Uniprot ID	Details
Serum paraoxonase/lactonase 3	PON3	7q21.3	Q15166	details
Serum paraoxonase/arylesterase 1	PON1	7q21.3	P27169	details
Serum paraoxonase/arylesterase 2	PON2	7q21.3	Q15165	details
Intestinal-type alkaline phosphatase	ALPI	2q37.1	P09923	details
Lysosomal acid phosphatase	ACP2	11p12-p11	P11117	details
Alkaline phosphatase, tissue-nonspecific isozyme	ALPL	1p36.12	P05186	details
Tartrate-resistant acid phosphatase type 5	ACP5	19p13.2	P13686	details
Alkaline phosphatase, placental-like	ALPPL2	2q37	P10696	details
Aldehyde dehydrogenase X, mitochondrial	ALDH1B1	9p11.1	P30837	details
Sulfotransferase family cytosolic 2B member 1	SULT2B1	19q13.3	O00204	details
Sorbitol dehydrogenase	SORD	15q15.3	Q00796	details
Alcohol dehydrogenase [NADP(+)]	AKR1A1	1p33-p32	P14550	details
Alcohol dehydrogenase 4	ADH4	4q22	P08319	details
Alcohol dehydrogenase 1B	ADH1B	4q23	P00325	details
Alcohol dehydrogenase 1A	ADH1A	4q23	P07327	details
Alcohol dehydrogenase 6	ADH6	4q23	P28332	details
Beta-glucuronidase	GUSB	7q21.11	P08236	details
Plasma alpha-L-fucosidase	FUCA2	6q24	Q9BTY2	details
Trans-2-enoyl-CoA reductase, mitochondrial	MECR	1p35.3	Q9BV79	details
Lecithin retinol acyltransferase	LRAT	4q32.1	O95237	details
Nuclear receptor subfamily 1 group I member 3	NR1I3	1q23.3	Q14994	details
Zinc-binding alcohol dehydrogenase domain-containing protein 2	ZADH2	18q22.3	Q8N4Q0	details
Hydroxyacid-oxoacid transhydrogenase, mitochondrial	ADHFE1	8q13.1	Q8IWW8	details
Fatty acyl-CoA reductase 2	FAR2	12p11.22	Q96K12	details
Acyl-CoA wax alcohol acyltransferase 2	AWAT2	Xq13.1	Q6E213	details
Testicular acid phosphatase	ACPT	19q13.4	Q9BZG2	details
Carboxylesterase 5A	CES5A	16q12.2	Q6NT32	details
Acid phosphatase-like protein 2	ACPL2	3q23	Q8TE99	details
Synaptic vesicle membrane protein VAT-1 homolog-like	VAT1L	16q23.1	Q9HCJ6	details
Quinone oxidoreductase PIG3	TP53I3	2p23.3	Q53FA7	details
Synaptic vesicle membrane protein VAT-1 homolog	VAT1	17q21	Q99536	details

Transporters

Protein Name	Gene Name	Locus	Uniprot ID	Details
Serum paraoxonase/arylesterase 1	PON1	7q21.3	P27169	details

Metal Bindings

Protein Name	Gene Name	Locus	Uniprot ID	Details
Serum paraoxonase/lactonase 3	PON3	7q21.3	Q15166	details
Serum paraoxonase/arylesterase 2	PON2	7q21.3	Q15165	details
Intestinal-type alkaline phosphatase	ALPI	2q37.1	P09923	details
Alkaline phosphatase, tissue-nonspecific isozyme	ALPL	1p36.12	P05186	details
Alkaline phosphatase, placental-like	ALPPL2	2q37	P10696	details
Sorbitol dehydrogenase	SORD	15q15.3	Q00796	details
Alcohol dehydrogenase 4	ADH4	4q22	P08319	details
Alcohol dehydrogenase 1B	ADH1B	4q23	P00325	details
Alcohol dehydrogenase 1A	ADH1A	4q23	P07327	details
Alcohol dehydrogenase 6	ADH6	4q23	P28332	details
Trans-2-enoyl-CoA reductase, mitochondrial	MECR	1p35.3	Q9BV79	details
Nuclear receptor subfamily 1 group I member 3	NR1I3	1q23.3	Q14994	details
Zinc-binding alcohol dehydrogenase domain-containing protein 2	ZADH2	18q22.3	Q8N4Q0	details
Hydroxyacid-oxoacid transhydrogenase, mitochondrial	ADHFE1	8q13.1	Q8IWW8	details
Synaptic vesicle membrane protein VAT-1 homolog-like	VAT1L	16q23.1	Q9HCJ6	details
Quinone oxidoreductase PIG3	TP53I3	2p23.3	Q53FA7	details
Synaptic vesicle membrane protein VAT-1 homolog	VAT1	17q21	Q99536	details
Reticulon-4-interacting protein 1, mitochondrial	RTN4IP1	6q21	Q8WWV3	details

Receptors

Protein Name	Gene Name	Locus	Uniprot ID	Details
Nuclear receptor subfamily 1 group I member 3	NR1I3	1q23.3	Q14994	details
Klotho	KL	13q12	Q9UEF7	details

Transcriptional Factors

Protein Name	Gene Name	Locus	Uniprot ID	Details
Nuclear receptor subfamily 1 group I member 3	NR1I3	1q23.3	Q14994	details

Concentrations Data

Not Available

External Links

HMDB ID

HMDB0012971

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FoodDB ID

KNApSAcK ID

Chemspider ID

KEGG Compound ID

BioCyc ID

BiGG ID

Not Available

Wikipedia Link

1-Hexanol

METLIN ID

Not Available

PubChem Compound

8103

PDB ID

HE2

ChEBI ID

87393

References

General References

Rice S, Koziel JA: Characterizing the Smell of Marijuana by Odor Impact of Volatile Compounds: An Application of Simultaneous Chemical and Sensory Analysis. PLoS One. 2015 Dec 10;10(12):e0144160. doi: 10.1371/journal.pone.0144160. eCollection 2015. [PubMed:26657499 ]

Only showing the first 10 proteins. There are 53 proteins in total.

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Enzymes

Enzyme Details

1. Serum paraoxonase/lactonase 3

General function:: Involved in arylesterase activity
Specific function:: Has low activity towards the organophosphate paraxon and aromatic carboxylic acid esters. Rapidly hydrolyzes lactones such as statin prodrugs (e.g. lovastatin). Hydrolyzes aromatic lactones and 5- or 6-member ring lactones with aliphatic substituents but not simple lactones or those with polar substituents.
Gene Name:: PON3
Uniprot ID:: Q15166
Molecular weight:: 39607.185

Enzyme Details

2. Serum paraoxonase/arylesterase 1

General function:: Involved in arylesterase activity
Specific function:: Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation.
Gene Name:: PON1
Uniprot ID:: P27169
Molecular weight:: 39730.99

Enzyme Details

3. Serum paraoxonase/arylesterase 2

General function:: Involved in arylesterase activity
Specific function:: Capable of hydrolyzing lactones and a number of aromatic carboxylic acid esters. Has antioxidant activity. Is not associated with high density lipoprotein. Prevents LDL lipid peroxidation, reverses the oxidation of mildly oxidized LDL, and inhibits the ability of MM-LDL to induce monocyte chemotaxis.
Gene Name:: PON2
Uniprot ID:: Q15165
Molecular weight:: 39380.535

Enzyme Details

4. Intestinal-type alkaline phosphatase

General function:: Involved in catalytic activity
Specific function:: Not Available
Gene Name:: ALPI
Uniprot ID:: P09923
Molecular weight:: 56811.695

Enzyme Details

5. Lysosomal acid phosphatase

General function:: Involved in acid phosphatase activity
Specific function:: Not Available
Gene Name:: ACP2
Uniprot ID:: P11117
Molecular weight:: 48343.92

Enzyme Details

6. Alkaline phosphatase, tissue-nonspecific isozyme

General function:: Involved in catalytic activity
Specific function:: This isozyme may play a role in skeletal mineralization.
Gene Name:: ALPL
Uniprot ID:: P05186
Molecular weight:: 57304.435

Enzyme Details

7. Tartrate-resistant acid phosphatase type 5

General function:: Involved in hydrolase activity
Specific function:: Involved in osteopontin/bone sialoprotein dephosphorylation. Its expression seems to increase in certain pathological states such as Gaucher and Hodgkin diseases, the hairy cell, the B-cell, and the T-cell leukemias.
Gene Name:: ACP5
Uniprot ID:: P13686
Molecular weight:: 36598.47

Enzyme Details

8. Alkaline phosphatase, placental-like

General function:: Involved in catalytic activity
Specific function:: Not Available
Gene Name:: ALPPL2
Uniprot ID:: P10696
Molecular weight:: 57376.515

Enzyme Details

9. Aldehyde dehydrogenase X, mitochondrial

General function:: Involved in oxidoreductase activity
Specific function:: ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation.
Gene Name:: ALDH1B1
Uniprot ID:: P30837
Molecular weight:: 57248.96

Enzyme Details

10. Sulfotransferase family cytosolic 2B member 1

General function:: Involved in sulfotransferase activity
Specific function:: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol, and isoform 2 avidly sulfonates pregnenolone but not cholesterol.
Gene Name:: SULT2B1
Uniprot ID:: O00204
Molecular weight:: 39598.595

Transporters

Enzyme Details

1. Serum paraoxonase/arylesterase 1

General function:: Involved in arylesterase activity
Specific function:: Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation.
Gene Name:: PON1
Uniprot ID:: P27169
Molecular weight:: 39730.99

Only showing the first 10 proteins. There are 53 proteins in total.

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Showing Compound Card for 1-Hexanol (CDB000490)

Structure for CDB000490 (1-Hexanol)

Enzymes

Transporters