| Identification |
|---|
| HMDB Protein ID
| CDBP04997 |
| Secondary Accession Numbers
| Not Available |
| Name
| Synaptic vesicle membrane protein VAT-1 homolog |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| VAT1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in zinc ion binding |
| Specific Function
| Possesses ATPase activity. Plays a part in calcium-regulated keratinocyte activation in epidermal repair mechanisms. Has no effect on cell proliferation |
| GO Classification
|
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| catalytic activity |
| transition metal ion binding |
| zinc ion binding |
| oxidoreductase activity |
| Process |
| metabolic process |
| oxidation reduction |
|
| Cellular Location
|
- Cytoplasm
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 17q21 |
| SNPs
| VAT1 |
| Gene Sequence
|
>1182 bp
ATGTCCGACGAGAGAGAGGTAGCCGAGGCAGCGACCGGGGAAGACGCCTCTTCGCCGCCT
CCGAAAACCGAGGCAGCGAGCGACCCCCAGCATCCCGCGGCCTCCGAAGGGGCCGCCGCC
GCCGCCGCCTCGCCGCCACTGCTGCGCTGCCTAGTGCTCACCGGCTTTGGAGGCTACGAC
AAGGTGAAGCTGCAGAGCCGGCCGGCAGCGCCCCCGGCCCCTGGGCCCGGCCAGCTGACG
CTGCGTCTGCGGGCCTGCGGGCTCAACTTCGCAGACCTCATGGCTAGGCAGGGGCTGTAC
GACCGTCTCCCGCCTCTGCCTGTCACTCCGGGCATGGAGGGCGCGGGTGTTGTGATCGCA
GTGGGCGAGGGAGTCAGCGACCGCAAGGCAGGAGACCGGGTGATGGTGTTGAACCGGTCA
GGGATGTGGCAGGAAGAGGTGACTGTGCCCTCGGTCCAGACCTTCCTGATTCCTGAGGCC
ATGACCTTTGAGGAAGCTGCTGCCTTGCTCGTCAATTACATTACAGCCTACATGGTCCTC
TTTGACTTCGGCAACCTACAGCCTGGCCACAGCGTCTTGGTACACATGGCTGCAGGGGGT
GTGGGTATGGCTGCCGTGCAGCTGTGCCGTACAGTGGAGAATGTGACAGTGTTCGGAACG
GCCTCGGCCAGCAAGCACGAGGCACTGAAGGAGAATGGGGTCACACATCCCATCGACTAT
CACACGACTGACTACGTGGATGAGATCAAGAAGATTTCCCCTAAAGGAGTGGACATTGTC
ATGGACCCTCTGGGTGGGTCAGATACTGCCAAGGGCTACAACCTCCTGAAACCCATGGGC
AAAGTCGTCACCTATGGAATGGCCAACCTGCTGACGGGCCCCAAACGGAACCTGATGGCC
CTGGCCCGGACATGGTGGAATCAGTTCAGCGTGACAGCTCTGCAGCTGCTGCAGGCCAAC
CGGGCTGTGTGTGGCTTCCACCTGGGCTACCTGGATGGTGAGGTGGAGCTGGTCAGTGGT
GTGGTGGCCCGCCTCCTGGCTCTGTACAACCAGGGCCACATCAAGCCCCACATTGACTCA
GTCTGGCCCTTCGAGAAGGTGGCTGATGCCATGAAACAGATGCAGGAGAAGAAGAATGTG
GGCAAGGTCCTCCTGGTTCCAGGGCCAGAGAAGGAGAACTAG
|
| Protein Properties |
|---|
| Number of Residues
| 393 |
| Molecular Weight
| 41920.0 |
| Theoretical pI
| 6.25 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Synaptic vesicle membrane protein VAT-1 homolog
MSDEREVAEAATGEDASSPPPKTEAASDPQHPAASEGAAAAAASPPLLRCLVLTGFGGYD
KVKLQSRPAAPPAPGPGQLTLRLRACGLNFADLMARQGLYDRLPPLPVTPGMEGAGVVIA
VGEGVSDRKAGDRVMVLNRSGMWQEEVTVPSVQTFLIPEAMTFEEAAALLVNYITAYMVL
FDFGNLQPGHSVLVHMAAGGVGMAAVQLCRTVENVTVFGTASASKHEALKENGVTHPIDY
HTTDYVDEIKKISPKGVDIVMDPLGGSDTAKGYNLLKPMGKVVTYGMANLLTGPKRNLMA
LARTWWNQFSVTALQLLQANRAVCGFHLGYLDGEVELVSGVVARLLALYNQGHIKPHIDS
VWPFEKVADAMKQMQEKKNVGKVLLVPGPEKEN
|
| External Links |
|---|
| GenBank ID Protein
| 158261943 |
| UniProtKB/Swiss-Prot ID
| Q99536 |
| UniProtKB/Swiss-Prot Entry Name
| VAT1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AK290460 |
| GeneCard ID
| VAT1 |
| GenAtlas ID
| VAT1 |
| HGNC ID
| HGNC:16919 |
| References |
|---|
| General References
| Not Available |