| Identification |
|---|
| HMDB Protein ID
| CDBP05016 |
| Secondary Accession Numbers
| Not Available |
| Name
| Reticulon-4-interacting protein 1, mitochondrial |
| Description
| Not Available |
| Synonyms
|
- NOGO-interacting mitochondrial protein
|
| Gene Name
| RTN4IP1 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in zinc ion binding |
| Specific Function
| Appears to be a potent inhibitor of regeneration following spinal cord injury |
| GO Classification
|
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| catalytic activity |
| transition metal ion binding |
| zinc ion binding |
| oxidoreductase activity |
| Process |
| metabolic process |
| oxidation reduction |
|
| Cellular Location
|
- Mitochondrion
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:6 |
| Locus
| 6q21 |
| SNPs
| RTN4IP1 |
| Gene Sequence
|
>1191 bp
ATGGAATTTCTGAAGACTTGTGTACTTAGAAGAAATGCATGCACTGCGGTTTGCTTCTGG
AGAAGCAAAGTTGTCCAAAAGCCTTCAGTTAGAAGGATTAGTACTACCTCTCCTAGGAGC
ACTGTCATGCCTGCTTGGGTGATAGATAAATATGGGAAGAATGAAGTGCTTCGATTCACT
CAGAACATGATGATGCCTATCATACACTATCCAAATGAAGTCATTGTCAAAGTTCACGCT
GCCAGTGTAAATCCTATAGACGTTAATATGAGAAGTGGTTATGGAGCTACAGCTTTAAAT
ATGAAGCGTGATCCTTTACACGTGAAAATCAAAGGAGAAGAATTTCCTCTGACTCTGGGT
CGGGATGTCTCTGGCGTGGTGATGGAATGTGGGCTTGATGTGAAATACTTCAAGCCTGGA
GATGAGGTCTGGGCTGCAGTTCCTCCTTGGAAACAAGGCACTCTTTCAGAGTTTGTTGTA
GTCAGTGGGAATGAGGTCTCTCACAAACCCAAATCACTCACTCATACTCAAGCTGCCTCT
TTGCCATATGTGGCTCTCACAGCCTGGTCTGCTATAAACAAAGTTGGTGGCCTGAATGAC
AAGAATTGCACAGGAAAACGTGTTCTAATCTTAGGCGCTTCAGGCGGAGTTGGTACTTTT
GCTATACAGGTAATGAAAGCATGGGATGCTCATGTGACAGCAGTTTGCTCCCAAGATGCC
AGTGAACTTGTAAGGAAGCTTGGTGCAGACGATGTAATTGATTACAAATCTGGAAGTGTG
GAAGAGCAGTTGAAATCCTTAAAACCATTTGATTTTATCCTTGATAATGTTGGCGGATCC
ACTGAAACATGGGCTCCAGATTTTCTCAAGAAATGGTCAGGAGCCACCTATGTGACTTTG
GTGACTCCTTTCCTCCTGAACATGGACCGATTGGGCATAGCAGATGGCATGTTGCAGACA
GGAGTCACTGTAGGTTCAAAGGCATTAAAGCATTTCTGGAAAGGAGTCCATTATCGCTGG
GCATTTTTCATGGCCAGTGGCCCATGTTTAGATGACATTGCAGAACTGGTGGATGCGGGA
AAGATCCGGCCAGTTATTGAACAAACCTTTCCTTTTTCTAAAGTTCCAGAAGCCTTCCTG
AAGGTGGAAAGAGGACACGCACGAGGAAAGACTGTAATTAATGTTGTTTAA
|
| Protein Properties |
|---|
| Number of Residues
| 396 |
| Molecular Weight
| 43589.4 |
| Theoretical pI
| 9.58 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Reticulon-4-interacting protein 1, mitochondrial
MEFLKTCVLRRNACTAVCFWRSKVVQKPSVRRISTTSPRSTVMPAWVIDKYGKNEVLRFT
QNMMMPIIHYPNEVIVKVHAASVNPIDVNMRSGYGATALNMKRDPLHVKIKGEEFPLTLG
RDVSGVVMECGLDVKYFKPGDEVWAAVPPWKQGTLSEFVVVSGNEVSHKPKSLTHTQAAS
LPYVALTAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFAIQVMKAWDAHVTAVCSQDA
SELVRKLGADDVIDYKSGSVEEQLKSLKPFDFILDNVGGSTETWAPDFLKKWSGATYVTL
VTPFLLNMDRLGIADGMLQTGVTVGSKALKHFWKGVHYRWAFFMASGPCLDDIAELVDAG
KIRPVIEQTFPFSKVPEAFLKVERGHARGKTVINVV
|
| External Links |
|---|
| GenBank ID Protein
| 47519420 |
| UniProtKB/Swiss-Prot ID
| Q8WWV3 |
| UniProtKB/Swiss-Prot Entry Name
| RT4I1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_032730.4 |
| GeneCard ID
| RTN4IP1 |
| GenAtlas ID
| RTN4IP1 |
| HGNC ID
| HGNC:18647 |
| References |
|---|
| General References
| Not Available |