Showing Protein Ghrelin O-acyltransferase (CDBP05625)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP05625
Secondary Accession Numbers Not Available
Name Ghrelin O-acyltransferase
Description Not Available
Synonyms Not Available
Gene Name MBOAT4
Protein Type Enzyme
Biological Properties
General Function serine O-acyltransferase activity
Specific Function Mediates the octanoylation of ghrelin at 'Ser-3'. Can use a variety of fatty acids as substrates including octanoic acid, decanoic acid and tetradecanoic acid.
GO Classification
Biological Process
peptidyl-serine octanoylation
Cellular Component
endoplasmic reticulum membrane
integral to endoplasmic reticulum membrane
Molecular Function
O-acyltransferase activity
serine O-acyltransferase activity
Cellular Location
  1. Endoplasmic reticulum membrane
Pathways
Gene Properties
Chromosome Location 8
Locus 8p12
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 435
Molecular Weight 49715.51
Theoretical pI Not Available
Pfam Domain Function
Signals Not Available
Transmembrane Regions
  • ["6-26", "43-63", "163-183", "241-261", "345-365", "377-397", "407-427"]
Protein Sequence 
>Ghrelin O-acyltransferase
MEWLWLFFLHPISFYQGAAFPFALLFNYLCIMDSFSTRARYLFLLTGGGALAVAAMGSYA
VLVFTPAVCAVALLCSLAPQQVHRWTFCFQMSWQTLCHLGLHYTEYYLHEPPSVRFCITL
SSLMLLTQRVTSLSLDICEGKVKAASGGFRSRSSLSEHVCKALPYFSYLLFFPALLGGSL
CSFQRFQARVQGSSALHPRHSFWALSWRGLQILGLECLNVAVSRVVDAGAGLTDCQQFEC
IYVVWTTAGLFKLTYYSHWILDDSLLHAAGFGPELGQSPGEEGYVPDADIWTLERTHRIS
VFSRKWNQSTARWLRRLVFQHSRAWPLLQTFAFSAWWHGLHPGQVFGFVCWAVMVEADYL
IHSFANEFIRSWPMRLFYRTLTWAHTQLIIAYIMLAVEVRSLSSLWLLCNSYNSVFPMVY
CILLLLLAKRKHKCN
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q96T53
UniProtKB/Swiss-Prot Entry Name MBOA4_HUMAN
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID HGNC:32311
References
General References Not Available