| Identification |
|---|
| HMDB Protein ID
| CDBP05441 |
| Secondary Accession Numbers
| Not Available |
| Name
| HERV-K_19q12 provirus ancestral Pol protein |
| Description
| Not Available |
| Synonyms
|
- HERV-K(C19) Pol protein
|
| Gene Name
| ERVK6 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Early post-infection, the reverse transcriptase converts the viral RNA genome into double-stranded viral DNA. The RNase H domain of the reverse transcriptase performs two functions. It degrades the RNA template and specifically removes the RNA primer from the RNA/DNA hybrid. Following nuclear import, the integrase catalyzes the insertion of the linear, double-stranded viral DNA into the host cell chromosome. Endogenous Pol proteins may have kept, lost or modified their original function during evolution.
|
| GO Classification
|
| Biological Process |
| DNA integration |
| RNA-dependent DNA replication |
| nucleic acid phosphodiester bond hydrolysis |
| DNA recombination |
| Molecular Function |
| RNA-directed DNA polymerase activity |
| DNA binding |
| metal ion binding |
| zinc ion binding |
| RNA binding |
| ribonuclease H activity |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| Not Available |
| Molecular Weight
| Not Available |
| Theoretical pI
| Not Available |
| Pfam Domain Function
|
Not Available |
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q9WJR5 |
| UniProtKB/Swiss-Prot Entry Name
| Not Available |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| HGNC:13915 |
| References |
|---|
| General References
| Not Available |