| Identification |
|---|
| HMDB Protein ID
| CDBP05337 |
| Secondary Accession Numbers
| Not Available |
| Name
| Inactive heparanase-2 |
| Description
| Not Available |
| Synonyms
|
- Hpa2
|
| Gene Name
| HPSE2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Binds heparin and heparan sulfate with high affinity, but lacks heparanase activity. Inhibits HPSE, possibly by competing for its substrates (in vitro).
|
| GO Classification
|
| Biological Process |
| small molecule metabolic process |
| glycosaminoglycan catabolic process |
| carbohydrate metabolic process |
| Cellular Component |
| intracellular |
| plasma membrane |
| proteinaceous extracellular matrix |
| Molecular Function |
| heparanase activity |
| cation binding |
| heparan sulfate proteoglycan binding |
|
| Cellular Location
|
Not Available
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Glycosaminoglycan degradation | Not Available |  | | Proteoglycans in cancer | Not Available |  |
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| Not Available |
| Molecular Weight
| Not Available |
| Theoretical pI
| Not Available |
| Pfam Domain Function
|
Not Available |
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q8WWQ2 |
| UniProtKB/Swiss-Prot Entry Name
| Not Available |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| HGNC:18374 |
| References |
|---|
| General References
| Not Available |