| Identification |
|---|
| HMDB Protein ID
| CDBP05132 |
| Secondary Accession Numbers
| Not Available |
| Name
| 14 kDa phosphohistidine phosphatase |
| Description
| Not Available |
| Synonyms
|
- Phosphohistidine phosphatase 1
- Protein janus-A homolog
|
| Gene Name
| PHPT1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in phosphohistidine phosphatase activity |
| Specific Function
| Exhibits phosphohistidine phosphatase activity.
|
| GO Classification
|
| Biological Process |
| negative regulation of ATP citrate synthase activity |
| negative regulation of lyase activity |
| peptidyl-histidine dephosphorylation |
| regulation of actin cytoskeleton reorganization |
| positive regulation of cell motility |
| negative regulation of T cell receptor signaling pathway |
| Cellular Component |
| cytosol |
| Molecular Function |
| phosphoprotein phosphatase activity |
| phosphohistidine phosphatase activity |
| calcium channel inhibitor activity |
|
| Cellular Location
|
- Cytoplasm
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Fructose and mannose metabolism | Not Available |  | | Fructose and Mannose Degradation |    | | | Fructosuria |    | Not Available | | Fructose intolerance, hereditary |    | Not Available |
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| PHPT1 |
| Gene Sequence
|
>378 bp
ATGGCGGTGGCGGACCTCGCTCTCATTCCTGATGTGGACATCGACTCCGACGGCGTCTTC
AAGTATGTGCTGATCCGAGTCCACTCGGCTCCCCGCTCCGGGGCTCCGGCTGCAGAGAGC
AAGGAGATCGTGCGCGGCTACAAGTGGGCTGAGTACCATGCGGACATCTACGACAAAGTG
TCGGGCGACATGCAGAAGCAAGGCTGCGACTGTGAGTGTCTGGGCGGCGGGCGCATCTCC
CACCAGAGTCAGGACAAGAAGATTCACGTGTACGGCTATTCCATGGCCTATGGTCCTGCC
CAGCACGCCATTTCAACTGAGAAAATCAAAGCCAAGTACCCCGACTACGAGGTCACCTGG
GCTAACGACGGCTACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 125 |
| Molecular Weight
| Not Available |
| Theoretical pI
| Not Available |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>14 kDa phosphohistidine phosphatase
MAVADLALIPDVDIDSDGVFKYVLIRVHSAPRSGAPAAESKEIVRGYKWAEYHADIYDKV
SGDMQKQGCDCECLGGGRISHQSQDKKIHVYGYSMAYGPAQHAISTEKIKAKYPDYEVTW
ANDGY
|
| External Links |
|---|
| GenBank ID Protein
| 8895093 |
| UniProtKB/Swiss-Prot ID
| Q9NRX4 |
| UniProtKB/Swiss-Prot Entry Name
| PHP14_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AF164795 |
| GeneCard ID
| PHPT1 |
| GenAtlas ID
| PHPT1 |
| HGNC ID
| HGNC:30033 |
| References |
|---|
| General References
| Not Available |