Showing Protein Ubiquitin carboxyl-terminal hydrolase 38 (CDBP05114)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP05114
Secondary Accession Numbers Not Available
Name Ubiquitin carboxyl-terminal hydrolase 38
Description Not Available
Synonyms
  1. Deubiquitinating enzyme 38
  2. HP43.8KD
  3. Ubiquitin thiolesterase 38
  4. Ubiquitin-specific-processing protease 38
Gene Name USP38
Protein Type Enzyme
Biological Properties
General Function Involved in ubiquitin thiolesterase activity
Specific Function Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C- terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal)
GO Classification
Function
hydrolase activity, acting on ester bonds
catalytic activity
hydrolase activity
ubiquitin thiolesterase activity
thiolester hydrolase activity
Process
metabolic process
catabolic process
macromolecule catabolic process
cellular macromolecule catabolic process
modification-dependent macromolecule catabolic process
modification-dependent protein catabolic process
ubiquitin-dependent protein catabolic process
Cellular Location
  1. Cytoplasmic
Pathways
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs USP38
Gene Sequence 
>3129 bp
ATGGACAAGATCCTGGAGGGCCTTGTGAGTTCCTCGCATCCCCTGCCCCTCAAGCGGGTG
ATTGTGCGGAAGGTGGTGGAATCGGCGGAGCACTGGCTAGACGAGGCGCAGTGCGAGGCC
ATGTTTGACCTGACGACCCGGCTCATCCTGGAGGGCCAGGACCCTTTCCAGCGGCAGGTG
GGGCACCAGGTGCTGGAGGCCTACGCACGATACCACCGGCCAGAGTTCGAGTCCTTCTTC
AACAAGACCTTCGTGTTGGGCCTCCTTCATCAGGGCTACCACTCTCTGGACAGGAAGGAT
GTAGCCATCCTGGACTACATTCACAACGGCCTGAAGCTGATTATGAGCTGTCCGTCGGTG
CTGGATCTCTTTAGCCTCCTGCAGGTAGAGGTGTTACGGATGGTGTGTGAGAGGCCGGAG
CCGCAGCTCTGTGCCCGACTGAGCGACCTTCTGACCGACTTTGTGCAATGCATCCCCAAG
GGGAAATTGTCCATCACGTTCTGTCAACAGCTGGTTCGAACGATAGGCCATTTCCAGTGC
GTGTCCACCCAGGAAAGAGAGCTGCGGGAATATGTCTCCCAGGTGACAAAAGTGAGTAAC
TTGCTGCAGAACATCTGGAAGGCCGAGCCTGCCACACTACTGCCTTCCCTGCAAGAAGTT
TTTGCAAGCATCTCTTCCACAGATGCATCATTTGAACCTTCTGTAGCATTGGCAAGCCTT
GTGCAGCATATTCCTCTTCAGATGATTACAGTTCTCATCAGGAGCCTTACTACGGATCCA
AATGTAAAAGATGCAAGTATGACCCAAGCCCTTTGCAGAATGATTGACTGGCTATCCTGG
CCATTGGCTCAGCATGTGGATACATGGGTAATTGCACTCCTGAAAGGACTGGCAGCTGTC
CAGAAGTTTACTATTTTGATAGATGTTACTTTGCTGAAAATAGAACTGGTTTTTAATCGA
CTTTGGTTTCCTCTTGTGAGACCTGGTGCTCTTGCAGTTCTTTCTCACATGCTGCTTAGC
TTTCAGCATTCTCCAGAGGCGTTCCATTTGATTGTTCCTCATGTGGTTAATTTGGTTCAT
TCTTTCAAAAATGATGGTCTGCCTTCAAGTACAGCCTTCTTAGTACAATTAACAGAATTG
ATACACTGTATGATGTATCATTATTCTGGATTTCCAGATCTCTATGAACCTATTCTGGAG
GCAATAAAGGATTTTCCTAAGCCCAGTGAAGAGAAGATTAAGTTAATTCTCAATCAAAGT
GCCTGGACTTCTCAATCCAATTCTTTGGCGTCTTGCTTGTCTAGACTTTCTGGAAAATCT
GAAACTGGGAAAACTGGTCTTATTAACCTAGGAAATACATGTTATATGAACAGTGTTATA
CAAGCCTTGTTTATGGCCACAGATTTCAGGAGACAAGTATTATCTTTAAATCTAAATGGG
TGCAATTCATTAATGAAAAAATTACAGCATCTTTTTGCCTTTCTGGCCCATACACAGAGG
GAAGCATACGCACCTCGGATATTCTTTGAGGCTTCCAGACCTCCATGGTTTACTCCCAGA
TCACAGCAAGACTGTTCTGAATACCTCAGATTTCTCCTTGACAGGCTCCATGAAGAAGAA
AAGATCTTGAAAGTTCAGGCCTCACACAAGCCTTCTGAAATTCTGGAATGCAGTGAAACT
TCTTTACAGGAAGTAGCTAGTAAAGCAGCAGTACTAACAGAGACCCCTCGTACAAGTGAC
GGTGAGAAGACTTTAATAGAAAAAATGTTTGGAGGAAAACTACGAACTCACATACGTTGT
TTGAACTGCAGGAGTACCTCACAAAAAGTGGAAGCCTTTACAGATCTTTCGCTTGCCTTT
TGTCCTTCCTCTTCTTTGGAAAACATGTCTGTCCAAGATCCAGCATCATCACCCAGTATA
CAAGATGGTGGTCTAATGCAAGCCTCTGTACCCGGTCCTTCAGAAGAACCAGTAGTTTAT
AATCCAACAACAGCTGCCTTCATCTGTGACTCACTTGTGAATGAAAAAACCATAGGCAGT
CCTCCTAATGAGTTTTACTGTTCTGAAAACACTTCTGTCCCTAACGAATCTAACAAGATT
CTTGTTAATAAAGATGTACCTCAGAAACCAGGAGGTGAAACCACACCTTCAGTAACTGAC
TTACTAAATTATTTTTTGGCTCCAGAGATTCTTACTGGTGATAACCAATATTATTGTGAA
AACTGTGCCTCTCTGCAAAATGCTGAGAAAACTATGCAAATCACGGAGGAACCTGAATAC
CTTATTCTTACTCTCCTGAGATTTTCATATGATCAGAAGTATCATGTGAGAAGGAAAATT
TTAGACAATGTATCACTGCCACTGGTTTTGGAGTTGCCAGTTAAAAGAATTACTTCTTTC
TCTTCATTGTCAGAAAGTTGGTCTGTAGATGTTGACTTCACTGATCTTAGTGAGAACCTT
GCTAAAAAATTAAAGCCTTCAGGGACTGATGAAGCTTCCTGCACAAAATTGGTGCCCTAT
CTATTAAGTTCCGTTGTGGTTCACTCTGGTATATCCTCTGAAAGTGGGCATTACTATTCT
TATGCCAGGAATATCACAAGTACAGACTCTTCATATCAGATGTACCACCAGTCTGAGGCT
CTGGCATTAGCATCCTCCCAGAGTCATTTACTAGGGAGAGATAGTCCCAGTGCAGTTTTT
GAACAGGATTTGGAAAATAAGGAAATGTCAAAAGAATGGTTTTTATTTAATGACAGTAGA
GTGACATTTACTTCATTTCAGTCAGTCCAGAAAATTACGAGCAGGTTTCCAAAGGACACA
GCTTATGTGCTTTTGTATAAAAAACAGCATAGTACTAATGGTTTAAGTGGTAATAACCCA
ACCAGTGGACTCTGGATAAATGGAGACCCACCTCTACAGAAAGAACTTATGGATGCTATA
ACAAAAGACAATAAACTATATTTACAGGAACAAGAGTTGAATGCTCGAGCCCGGGCCCTC
CAAGCTGCATCTGCTTCATGTTCATTTCGGCCCAATGGATTTGATGACAACGACCCACCA
GGAAGCTGTGGACCAACTGGTGGAGGGGGTGGAGGAGGATTTAATACAGTTGGCAGACTC
GTATTTTGA
Protein Properties
Number of Residues 1042
Molecular Weight 116545.0
Theoretical pI 6.16
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Ubiquitin carboxyl-terminal hydrolase 38
MDKILEGLVSSSHPLPLKRVIVRKVVESAEHWLDEAQCEAMFDLTTRLILEGQDPFQRQV
GHQVLEAYARYHRPEFESFFNKTFVLGLLHQGYHSLDRKDVAILDYIHNGLKLIMSCPSV
LDLFSLLQVEVLRMVCERPEPQLCARLSDLLTDFVQCIPKGKLSITFCQQLVRTIGHFQC
VSTQERELREYVSQVTKVSNLLQNIWKAEPATLLPSLQEVFASISSTDASFEPSVALASL
VQHIPLQMITVLIRSLTTDPNVKDASMTQALCRMIDWLSWPLAQHVDTWVIALLKGLAAV
QKFTILIDVTLLKIELVFNRLWFPLVRPGALAVLSHMLLSFQHSPEAFHLIVPHVVNLVH
SFKNDGLPSSTAFLVQLTELIHCMMYHYSGFPDLYEPILEAIKDFPKPSEEKIKLILNQS
AWTSQSNSLASCLSRLSGKSETGKTGLINLGNTCYMNSVIQALFMATDFRRQVLSLNLNG
CNSLMKKLQHLFAFLAHTQREAYAPRIFFEASRPPWFTPRSQQDCSEYLRFLLDRLHEEE
KILKVQASHKPSEILECSETSLQEVASKAAVLTETPRTSDGEKTLIEKMFGGKLRTHIRC
LNCRSTSQKVEAFTDLSLAFCPSSSLENMSVQDPASSPSIQDGGLMQASVPGPSEEPVVY
NPTTAAFICDSLVNEKTIGSPPNEFYCSENTSVPNESNKILVNKDVPQKPGGETTPSVTD
LLNYFLAPEILTGDNQYYCENCASLQNAEKTMQITEEPEYLILTLLRFSYDQKYHVRRKI
LDNVSLPLVLELPVKRITSFSSLSESWSVDVDFTDLSENLAKKLKPSGTDEASCTKLVPY
LLSSVVVHSGISSESGHYYSYARNITSTDSSYQMYHQSEALALASSQSHLLGRDSPSAVF
EQDLENKEMSKEWFLFNDSRVTFTSFQSVQKITSRFPKDTAYVLLYKKQHSTNGLSGNNP
TSGLWINGDPPLQKELMDAITKDNKLYLQEQELNARARALQAASASCSFRPNGFDDNDPP
GSCGPTGGGGGGGFNTVGRLVF
GenBank ID Protein 27545313
UniProtKB/Swiss-Prot ID Q8NB14
UniProtKB/Swiss-Prot Entry Name UBP38_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_032557.5
GeneCard ID USP38
GenAtlas ID USP38
HGNC ID HGNC:20067
References
General References Not Available