| Identification |
|---|
| HMDB Protein ID
| CDBP05105 |
| Secondary Accession Numbers
| Not Available |
| Name
| Cyclin-dependent kinase 2-interacting protein |
| Description
| Not Available |
| Synonyms
|
- CDK2-interacting protein
|
| Gene Name
| CINP |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in cell cycle |
| Specific Function
| Interacts with the components of the replication complex and 2 kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication. Regulates ATR-mediated checkpoint signaling |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Nucleus
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 14q32.31 |
| SNPs
| CINP |
| Gene Sequence
|
>639 bp
ATGGAAGCAAAGACTCTTGGAACTGTAACGCCCAGAAAACCTGTCTTATCTGTCAGTGCA
AGAAAAATTAAGGACAATGCGGCTGATTGGCACAATTTAATCCTGAAGTGGGAAACCCTC
AATGATGCAGGTTTTACCACTGCAAATAATATTGCCAACTTGAAAATCAGTTTATTGAAT
AAAGACAAGATAGAACTAGACAGCAGCAGCCCAGCCTCGAAGGAAAATGAAGAAAAGGTG
TGTCTGGAATATAACGAGGAACTGGAGAAGCTGTGTGAGGAACTGCAGGCCACCTTGGAT
GGGTTGACCAAAATACAGGTGAAAATGGAAAAGCTGTCTTCAACTACCAAGGGAATTTGT
GAACTAGAAAACTACCATTATGGGGAGGAGAGTAAACGACCCCCTCTGTTCCACACGTGG
CCTACAACCCATTTCTATGAGGTTTCGCATAAGCTCTTGGAGATGTACAAGAAGGAGTTG
CTCTTGAAGCGCACGGTGGCCAAGGAGCTTGCCCACACCGGGAATCCGGACCTCACCTTG
AGCTACCTGTCCATGTGGTTGCACCAACCCTATGTTGAGAACGACAACAAGCTGCATCTG
GAGAACATGCTGCTGGAGACAGGCCACCGAGCTCTCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 212 |
| Molecular Weight
| 24323.6 |
| Theoretical pI
| 6.24 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Cyclin-dependent kinase 2-interacting protein
MEAKTLGTVTPRKPVLSVSARKIKDNAADWHNLILKWETLNDAGFTTANNIANLKISLLN
KDKIELDSSSPASKENEEKVCLEYNEELEKLCEELQATLDGLTKIQVKMEKLSSTTKGIC
ELENYHYGEESKRPPLFHTWPTTHFYEVSHKLLEMYRKELLLKRTVAKELAHTGDPDLTL
SYLSMWLHQPYVESDSRLHLESMLLETGHRAL
|
| External Links |
|---|
| GenBank ID Protein
| 7274384 |
| UniProtKB/Swiss-Prot ID
| Q9BW66 |
| UniProtKB/Swiss-Prot Entry Name
| CINP_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF228148 |
| GeneCard ID
| CINP |
| GenAtlas ID
| CINP |
| HGNC ID
| HGNC:23789 |
| References |
|---|
| General References
| Not Available |