| Identification |
|---|
| HMDB Protein ID
| CDBP05091 |
| Secondary Accession Numbers
| Not Available |
| Name
| Ras-GEF domain-containing family member 1C |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| RASGEF1C |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in guanyl-nucleotide exchange factor activity |
| Specific Function
| Guanine nucleotide exchange factor (GEF) |
| GO Classification
|
| Component |
| cell part |
| intracellular |
| Function |
| enzyme regulator activity |
| nucleoside-triphosphatase regulator activity |
| gtpase regulator activity |
| guanyl-nucleotide exchange factor activity |
| Process |
| regulation of signal transduction |
| regulation of small gtpase mediated signal transduction |
| biological regulation |
| regulation of biological process |
| regulation of cellular process |
| signal transduction |
| intracellular signal transduction |
| small gtpase mediated signal transduction |
| regulation of cell communication |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q35.3 |
| SNPs
| RASGEF1C |
| Gene Sequence
|
>1401 bp
ATGCCACAGACGCTGAGTGCCTCCGACATGGTCACCCCAGGCAGCCTCAGCCCACCCCCC
ACCGAGCCCACAGATGGCGAACAGGCTGGGCAGCCCCTCCTGGATGGAGCGCCATCCTCA
GCCTCCCTGGAAACACTGATCCAGCACCTGGTGCCCACAGCCGACTACTACCCCGAGAAA
GCCTACATCTTCACCTTCCTGCTGAGCTCTCGCCTCTTCATCGAGCCCCGGGAGCTCCTG
GCCCGGGTCTGCCACCTGTGCATCGAGCAGCAGCAGCTGGACAAGCCGGTGCTGGACAAG
GCCCGGGTCCGGAAGTTCGGCCCCAAACTGCTGCAGCTGTTGGCCGAGTGGACCGAGACC
TTCCCAAGGGACTTCCAGGAGGAGTCGACTATCGGGCACCTTAAGGACGTCGTGGGCCGC
ATCGCCCCCTGTGACGAGGCATACCGGAAGAGGATGCATCAGCTCCTACAGGCTCTGCAC
CAGAAGCTGGCGGCTCTGCGCCAGGGGCCAGAAGGTCTGGTGGGTGCCGACAAGCCCATC
TCCTACAGGACCAAGCCACCAGCCTCCATCCACAGGGAGCTCCTTGGTGTCTGCAGCGAC
CCCTACACACTGGCCCAGCAGCTGACCCACGTGGAACTGGAGCGGCTGCGGCACATCGGG
CCTGAGGAGTTTGTCCAGGCCTTTGTGAACAAGGACCCTCTGGCCAGCACAAAGCCCTGC
TTCAGTGACAAGACCAGCAACCTGGAGGCTTATGTGAAATGGTTCAACAGGCTGTGCTAC
CTGGTGGCAACTGAGATCTGCATGCCAGCCAAGAAGAAGCAGAGGGCCCAGGTGATTGAG
TTCTTCATCGACGTGGCCCGCGAGTGCTTCAACATCGGCAACTTCAACTCCCTCATGGCC
ATCATCTCCGGCATGAACATGAGCCCTGTCTCCAGGCTGAAGAAGACCTGGGCCAAAGTG
AGGACGGCCAAGTTTTTCATCCTCGAGCACCAGATGGACCCAACGGGGAATTTCTGCAAC
TACAGGACAGCCCTGCGCGGGGCGGCCCACCGCTCCCTGACGGCCCACAGCAGCCGAGAG
AAGATTGTCATTCCTTTCTTCAGCCTGCTCATCAAAGACATCTACTTCCTGAATGAGGGC
TGCGCCAACCGCCTTCCCAATGGACACGTCAACTTTGAGAAATTCCTGGAGCTGGCCAAG
CAGGTGGGGGAGTTCATCACCTGGAAACAAGTGGAGTGTCCCTTCGAGCAAGACGCCAGC
ATCACCCACTACCTGTACACCGCCCCCATCTTCAGTGAGGATGGTCTTTATTTGGCTTCT
TATGAAAGTGAGAGCCCAGAGAACCAAACAGAAAAAGAAAGATGGAAAGCTCTAAGATCT
TCTATTTTGGGGAAGACATGA
|
| Protein Properties |
|---|
| Number of Residues
| 466 |
| Molecular Weight
| 52869.3 |
| Theoretical pI
| 7.72 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Ras-GEF domain-containing family member 1C
MPQTLSASDMVTPGSLSPPPTEPTDGEQAGQPLLDGAPSSASLETLIQHLVPTADYYPEK
AYIFTFLLSSRLFIEPRELLARVCHLCIEQQQLDKPVLDKARVRKFGPKLLQLLAEWTET
FPRDFQEESTIGHLKDVVGRIAPCDEAYRKRMHQLLQALHQKLAALRQGPEGLVGADKPI
SYRTKPPASIHRELLGVCSDPYTLAQQLTHVELERLRHIGPEEFVQAFVNKDPLASTKPC
FSDKTSNLEAYVKWFNRLCYLVATEICMPAKKKQRAQVIEFFIDVARECFNIGNFNSLMA
IISGMNMSPVSRLKKTWAKVRTAKFFILEHQMDPTGNFCNYRTALRGAAHRSLTAHSSRE
KIVIPFFSLLIKDIYFLNEGCANRLPNGHVNFEKFLELAKQVGEFITWKQVECPFEQDAS
ITHYLYTAPIFSEDGLYLASYESESPENQTEKERWKALRSSILGKT
|
| External Links |
|---|
| GenBank ID Protein
| 33187643 |
| UniProtKB/Swiss-Prot ID
| Q8N431 |
| UniProtKB/Swiss-Prot Entry Name
| RGF1C_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF449764 |
| GeneCard ID
| RASGEF1C |
| GenAtlas ID
| RASGEF1C |
| HGNC ID
| HGNC:27400 |
| References |
|---|
| General References
| Not Available |