| Identification |
|---|
| HMDB Protein ID
| CDBP05080 |
| Secondary Accession Numbers
| Not Available |
| Name
| Guanine nucleotide exchange factor for Rab-3A |
| Description
| Not Available |
| Synonyms
|
- Rab-3A-interacting-like protein 1
- Rab3A-interacting-like protein 1
- Rabin3-like 1
|
| Gene Name
| RAB3IL1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in guanyl-nucleotide exchange factor activity |
| Specific Function
| Guanine nucleotide exchange factor (GEF) for Rab3A, a GTPase that regulates synaptic vesicle exocytosis |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 11q12.2 |
| SNPs
| RAB3IL1 |
| Gene Sequence
|
>1149 bp
ATGTGGAGCGGCCCACCCCAGCCAGACCAGGGCCTCCCGCCGCCCCTTGCAGCTGTCCCG
GTCCCCTGGAAGAGCACGGACCCCTGCCAAGGCCACAGGGAGTCCCCAGGAGCCCTGGTG
GAGACCTCTGCAGGGGAGGAGGCCCAAGGCCAGGAGGGCCCCGCAGCCGCCCAGCTGGAC
GTGTTGCGCCTGCGCAGCTCTTCCATGGAGATCCGAGAGAAGGGCTCCGAGTTCCTGAAG
GAGGAGCTGCACAGAGCGCAGAAGGAGCTGAAGCTAAAGGACGAGGAATGTGAGCGGCTG
TCCAAGGTGCGGGAGCAGCTAGAACAGGAGCTGGAAGAGCTGACGGCCAGCCTGTTTGAG
GAAGCTCACAAGATGGTTCGAGAAGCCAACATGAAGCAGGCGGCATCAGAAAAGCAGCTG
AAGGAGGCTCGGGGCAAGATCGACATGCTGCAGGCAGAGGTGACAGCCTTGAAGACACTG
GTCATCACGTCCACACCAGCCTCTCCCAACCGCGAGCTTCACCCCCAGCTGCTGAGCCCC
ACCAAGGCCGGGCCCCGAAAGGGCCACTCTCGCCACAAGAGCACCAGCAGCACCCTCTGC
CCCGCCGTGTGTCCCGCTGCGGGACACACCCTCACCCCAGACAGAGAGGGCAAGGAGGTG
GACACAATCCTGTTTGCAGAGTTCCAGGCCTGGAGGGAATCCCCCACCCTGGACAAGACC
TGCCCCTTCCTGGAAAGGGTGTACCGAGAGGACGTGGGCCCCTGCCTGGACTTCACAATG
CAGGAGCTCTCGGTGCTGGTACGGGCCGCCGTGGAGGACAACACGCTCACCATTGAGCCG
GTGGCTTCGCAGACGCTGCCCACAGTGAAGGTGGCCGAGGTTGACTGTAGCAGCACCAAC
ACATGTGCCCTGAGCGGGCTGACCCGCACCTGCCGCCACCGAATCCGGCTCGGGGACTCC
AAAAGCCATTACTACATCTCGCCATCTTCCCGGGCCAGGATCACCGCAGTGTGCAACTTC
TTCACCTACATCCGCTACATCCAGCAAGGCCTGGTGCGGCAGGACGCAGAGCCCATGTTC
TGGGAGATCATGAGGTTGCGGAAGGAGATGTCACTGGCCAAGCTCGGCTTCTTCCCCCAG
GAGGCTTAG
|
| Protein Properties |
|---|
| Number of Residues
| 382 |
| Molecular Weight
| 42636.2 |
| Theoretical pI
| 6.43 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Guanine nucleotide exchange factor for Rab-3A
MWSGPPQPDQGLPPPLAAVPVPWKSTDPCQGHRESPGALVETSAGEEAQGQEGPAAAQLD
VLRLRSSSMEIREKGSEFLKEELHRAQKELKLKDEECERLSKVREQLEQELEELTASLFE
EAHKMVREANMKQAASEKQLKEARGKIDMLQAEVTALKTLVITSTPASPNRELHPQLLSP
TKAGPRKGHSRHKSTSSTLCPAVCPAAGHTLTPDREGKEVDTILFAEFQAWRESPTLDKT
CPFLERVYREDVGPCLDFTMQELSVLVRAAVEDNTLTIEPVASQTLPTVKVAEVDCSSTN
TCALSGLTRTCRHRIRLGDSKSHYYISPSSRARITAVCNFFTYIRYIQQGLVRQDAEPMF
WEIMRLRKEMSLAKLGFFPQEA
|
| External Links |
|---|
| GenBank ID Protein
| 21361440 |
| UniProtKB/Swiss-Prot ID
| Q8TBN0 |
| UniProtKB/Swiss-Prot Entry Name
| R3GEF_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_013401.2 |
| GeneCard ID
| RAB3IL1 |
| GenAtlas ID
| RAB3IL1 |
| HGNC ID
| HGNC:9780 |
| References |
|---|
| General References
| Not Available |