Showing Protein Ras-specific guanine nucleotide-releasing factor RalGPS1 (CDBP05071)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 3 compounds
Identification
HMDB Protein ID CDBP05071
Secondary Accession Numbers Not Available
Name Ras-specific guanine nucleotide-releasing factor RalGPS1
Description Not Available
Synonyms
  1. Ral GEF with PH domain and SH3-binding motif 1
  2. Ral guanine nucleotide exchange factor 2
  3. RalA exchange factor RalGPS1
  4. RalGEF 2
Gene Name RALGPS1
Protein Type Enzyme
Biological Properties
General Function Involved in guanyl-nucleotide exchange factor activity
Specific Function May be involved in cytoskeletal organization. May also be involved in the stimulation of transcription in a Ras-independent fashion. Guanine nucleotide exchange factor for the small GTPase RALA
GO Classification
Component
cell part
intracellular
Function
guanyl-nucleotide exchange factor activity
enzyme regulator activity
nucleoside-triphosphatase regulator activity
gtpase regulator activity
Process
biological regulation
regulation of biological process
regulation of cellular process
signal transduction
intracellular signal transduction
small gtpase mediated signal transduction
Cellular Location
  1. Cytoplasm
  2. Cell membrane (Probable)
Pathways
Gene Properties
Chromosome Location Chromosome:9
Locus 9q33.3
SNPs RALGPS1
Gene Sequence 
>1674 bp
ATGTACAAGAGGAATGGTCTGATGGCTAGCGTGTTGGTCACCTCTGCCACTCCACAGGGC
AGCAGCAGCTCGGACTCTCTGGAGGGCCAGAGCTGCGACTATGCCAGCAAGAGCTATGAT
GCCGTTGTCTTCGATGTCTTGAAAGTGACCCCAGAGGAGTTTGCTAGCCAGATTACATTA
ATGGATATACCTGTGTTTAAAGCTATCCAGCCGGAGGAACTAGCCAGCTGTGGATGGAGT
AAGAAGGAGAAACACAGTCTTGCCCCTAACGTTGTGGCCTTTACCCGGAGGTTTAACCAG
GTCAGTTTTTGGGTTGTACGAGAAATTCTAACAGCACAGACTTTAAAAATAAGGGCAGAA
ATCCTCAGCCATTTTGTGAAAATAGCCAAGAAACTTCTAGAACTCAACAACCTTCATTCT
CTCATGTCTGTGGTATCAGCATTACAAAGTGCTCCCATCTTCAGGCTGACAAAAACCTGG
GCTCTTTTAAATCGAAAAGACAAGACTACCTTTGAGAAATTGGACTACCTGATGTCGAAA
GAAGATAATTACAAGCGGACACGGGAATATATCCGAAGCCTGAAGATGGTTCCAAGTATT
CCCTATCTAGGAATCTATCTTCTGGATTTAATCTACATTGATTCTGCATATCCTGCCTCA
GGCAGTATCATGGAAAATGAACAAAGATCCAATCAGATGAACAATATTCTTCGAATAATT
GCTGATTTACAAGTTTCCTGCAGCTATGATCACCTCACCACCCTGCCCCATGTGCAGAAG
TACCTGAAGTCCGTACGCTACATTGAAGAGCTCCAGAAGTTTGTGGAAGACGACAACTAC
AAACTGTCGCTCAGAATCGAACCAGGAAGCAGCTCTCCAAGACTAGTCTCTTCCAAGGAA
GATCTTGCAGGTCCCTCTGCTGGCTCCGGTTCTGCGAGGTTCAGCCGGAGGCCCACCTGT
CCTGACACATCTGTTGCTGGCAGCCTCCCCACACCTCCAGTCCCCAGACACAGGAAGAGC
CACAGCCTAGGCAACAATATGATGTGTCAGTTGAGTGTAGTTGAGAGTAAAAGTGCGACA
TTCCCATCGGAGAAAGCAAGGCACCTACTGGACGACAGTGTCCTAGAGTCCCGCAGCCCC
CGAAGGGGCCTGGCTCTGACCTCCTCCTCTGCTGTCACCAATGGACTCTCCCTAGGCAGT
AGTGAGAGCTCAGAGTTTAGTGAAGAGATGTCTTCAGGGCTGGAAAGCCCCACCGGCCCG
TGCATCTGTTCTCTGGGGAACTCCGCAGCTGTGCCCACCATGGAGGGGCCTCTGAGAAGA
AAAACCCTGCTCAAGGAAGGGCGGAAGCCTGCGCTGTCCTCGTGGACCAGGTACTGGGTC
ATACTCTCAGGATCCACCCTCCTGTACTACGGAGCCAAGTCCTTGCGGGGCACAGACAGA
AAACACTATAAATCCACACCTGGCAAAAAGGTTTCCATCGTGGGCTGGATGGTGCAGCTG
CCCGATGACCCCGAGCACCCAGATATCTTCCAGCTGAACAACCCTGACAAAGGCAATGTT
TACAAGTTTCAGACTGGTTCCCGATTTCATGCAATACTGTGGCACAAGCATTTGGATGAT
GCATGTAAAAGCAACAGGCCTCAGGTACCTGCAAACCTTATGTCATTTGAGTAA
Protein Properties
Number of Residues 557
Molecular Weight 62132.4
Theoretical pI 9.52
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Ras-specific guanine nucleotide-releasing factor RalGPS1
MYKRNGLMASVLVTSATPQGSSSSDSLEGQSCDYASKSYDAVVFDVLKVTPEEFASQITL
MDIPVFKAIQPEELASCGWSKKEKHSLAPNVVAFTRRFNQVSFWVVREILTAQTLKIRAE
ILSHFVKIAKKLLELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKTTFEKLDYLMSK
EDNYKRTREYIRSLKMVPSIPYLGIYLLDLIYIDSAYPASGSIMENEQRSNQMNNILRII
ADLQVSCSYDHLTTLPHVQKYLKSVRYIEELQKFVEDDNYKLSLRIEPGSSSPRLVSSKE
DLAGPSAGSGSARFSRRPTCPDTSVAGSLPTPPVPRHRKSHSLGNNMMCQLSVVESKSAT
FPSEKARHLLDDSVLESRSPRRGLALTSSSAVTNGLSLGSSESSEFSEEMSSGLESPTGP
CICSLGNSAAVPTMEGPLRRKTLLKEGRKPALSSWTRYWVILSGSTLLYYGAKSLRGTDR
KHYKSTPGKKVSIVGWMVQLPDDPEHPDIFQLNNPDKGNVYKFQTGSRFHAILWHKHLDD
ACKSNRPQVPANLMSFE
GenBank ID Protein 7662070
UniProtKB/Swiss-Prot ID Q5JS13
UniProtKB/Swiss-Prot Entry Name RGPS1_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_014636.2
GeneCard ID RALGPS1
GenAtlas ID RALGPS1
HGNC ID HGNC:16851
References
General References Not Available