Showing Protein PH and SEC7 domain-containing protein 1 (CDBP05056)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 3 compounds
Identification
HMDB Protein ID CDBP05056
Secondary Accession Numbers Not Available
Name PH and SEC7 domain-containing protein 1
Description Not Available
Synonyms
  1. Exchange factor for ARF6
  2. Pleckstrin homology and SEC7 domain-containing protein 1
Gene Name PSD
Protein Type Enzyme
Biological Properties
General Function Involved in ARF guanyl-nucleotide exchange factor activity
Specific Function Guanine nucleotide exchange factor for ARF6
GO Classification
Component
cell part
intracellular
Function
small gtpase regulator activity
enzyme regulator activity
arf guanyl-nucleotide exchange factor activity
nucleoside-triphosphatase regulator activity
gtpase regulator activity
Process
regulation of ras protein signal transduction
biological regulation
regulation of biological process
regulation of arf protein signal transduction
regulation of cellular process
regulation of cell communication
regulation of signal transduction
regulation of small gtpase mediated signal transduction
Cellular Location Not Available
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 10q24
SNPs PSD
Gene Sequence 
>3075 bp
ATGGCCCAGGGTGCCATGCGCTTCTGCTCGGAAGGCGACTGTGCCATCTCCCCACCACGA
TGCCCACGCCGCTGGCTCCCCGAAGGCCCGGTGCCCCAGAGCCCCCCAGCCAGCATGTAT
GGCAGCACAGGCTCCTTGCTACGGCGAGTGGCAGGTCCAGGTCCTCGAGGCCGGGAACTG
GGACGTGTGACAGCACCCTGTACACCTCTGCGTGGCCCCCCCTCACCCCGTGTTGCTCCC
TCACCCTGGGCACCCTCTTCACCCACTGGGCAGCCCCCACCCGGGGCCCAGAGCTCTGTG
GTCATCTTCCGCTTTGTGGAGAAGGCCAGTGTGAGGCCACTGAATGGGCTACCTGCTCCA
GGGGGCTTGAGTCGGAGCTGGGATCTGGGTGGGGTTTCTCCTCCCAGGCCCACCCCAGCC
CTTGGGCCTGGCTCCAACCGGAAGTTACGGCTGGAAGCATCCACATCAGACCCACTCCCC
GCCAGAGGAGGCTCGGCCCTACCTGGCAGCCGGAACCTTGTACATGGGCCGCCAGCCCCA
CCCCAGGTTGGAGCAGATGGCCTTTACTCCTCTCTCCCCAATGGGCTGGGGGGCCCCCCT
GAGCGCCTGGCCACACTCTTCGGAGGACCTGCTGACACTGGATTCCTGAACCAGGGGGAT
ACCTGGTCCTCCCCCCGGGAAGTCTCCTCTCATGCCCAGAGAATCGCTAGAGCCAAATGG
GAATTCTTCTATGGCTCCTTGGACCCCCCCAGCTCAGGTGCTAAGCCCCCAGAGCAGGCC
CCCCCATCTCCACCTGGGGTGGGCTCAAGGCAGGGCTCTGGGGTGGCTGTGGGGCGAGCA
GCCAAGTACTCCGAGACAGACCTGGACACGGTGCCCCTGAGGTGCTACCGCGAGACTGAC
ATCGATGAGGTGCTGGCTGAGCGGGAGGAGGCCGACTCGGCCATCGAAAGTCAGCCCAGC
TCTGAGGGCCCACCAGGCACTGCCTACCCACCTGCCCCACGGCCCGGCCCACTCCCTGGC
CCTCATCCCAGCCTCGGCAGTGGCAATGAGGATGAGGACGACGATGAGGCAGGTGGGGAA
GAAGATGTGGACGACGAGGTGTTTGAGGCCTCTGAAGGGGCCCGGCCAGGGAGCCGGATG
CCTCTCAAGTCACCTGTGCCCTTTCTACCTGGGACGAGCCCCTCGGCTGATGGGCCTGAC
TCTTTCAGTTGTGTGTTCGAAGCCATCCTGGAGTCACACCGGGCCAAAGGCACCTCCTAT
ACCAGCCTCGCCTCGCTGGAGGCCTTGGCCTCACCTGGCCCAACCCAGAGCCCCTTCTTC
ACCTTTGAGCTGCCTCCCCAACCCCCTGCACCCCGGCCCGACCCACCAGCTCCCGCCCCA
CTTGCCCCTCTTGAACCGGATTCTGGTACCAGCTCTGCTGCTGATGGTCCTTGGACACAG
AGAGGGGAGGAGGAGGAGGCAGAGGCCAGAGCCAAGCTGGCCCCAGGGAGGGAGCCCCCT
AGTCCCTGCCACTCAGAGGACAGCCTTGGGCTGGGGGCAGCACCCCTTGGCAGCGAACCA
CCCCTGAGCCAGCTGGTGTCCGACTCAGACTCAGAGCTGGACAGCACAGAGCGGCTGGCC
CTGGGAAGCACAGACACCTTGTCCAATGGGCAGAAAGCGGACCTGGAGGCTGCGCAGCGC
CTGGCCAAGAGGCTGTACCGACTAGATGGCTTCAGGAAGGCCGATGTGGCCCGGCACCTG
GGCAAGAACAATGACTTCAGCAAACTGGTGGCTGGGGAGTACCTCAAGTTCTTTGTCTTC
ACGGGCATGACTCTGGACCAAGCTCTCAGGGTGTTTCTGAAGGAGCTGGCCTTAATGGGT
GAGACCCAGGAACGAGAGCGCGTGCTGGCCCACTTCTCCCAGCGATACTTCCAGTGCAAT
CCTGAAGCCCTGTCCTCAGAGGACGGCGCCCACACGCTGACCTGTGCGCTCATGCTGCTC
AACACGGATCTCCACGGCCATAACATCGGGAAGCGCATGACCTGCGGGGACTTCATCGGG
AACCTGGAGGGCCTCAATGATGGCGGCGACTTCCCTAGGGAGCTGCTCAAGGCCTTGTAC
AGCTCCATCAAGAATGAGAAGCTGCAGTGGGCCATAGACGAGGAGGAGCTGAGACGCTCT
CTGTCTGAGTTGGCCGACCCCAACCCCAAGGTCATCAAGCGGATCAGCGGGGGCAGTGGC
AGTGGCTCCAGCCCTTTCCTGGACCTGACTCCCGAGCCTGGGGCTGCCGTCTACAAGCAC
GGGGCCCTGGTGCGAAAGGTGCACGCAGACCCTGACTGCAGGAAGACACCTCGGGGCAAG
CGGGGCTGGAAGAGCTTCCACGGGATCCTCAAGGGCATGATCCTCTACCTGCAGAAGGAG
GAGTACAAGCCTGGGAAGGCCCTTTCAGAGACGGAGCTCAAGAATGCCATCAGCATCCAC
CATGCCCTGGCCACTCGTGCCAGTGACTACAGCAAGAGGCCCCACGTCTTCTACCTGCGC
ACAGCTGACTGGCGGGTCTTCCTCTTCCAGGCCCCGAGCCTGGAGCAGATGCAGTCCTGG
ATCACTCGCATCAATGTAGTAGCCGCTATGTTCTCTGCGCCCCCCTTCCCAGCTGCTGTT
AGCTCCCAAAAGAAGTTCAGCCGCCCTCTCCTGCCCAGCGCTGCCACCCGCCTCTCCCAG
GAGGAGCAGGTGCGGACCCACGAGGCCAAGCTGAAGGCCATGGCAAGTGAGCTGCGGGAG
CACCGGGCCGCCCAGCTGGGCAAGAAGGGCCGGGGCAAGGAGGCTGAAGAGCAGCGGCAG
AAGGAGGCCTACCTGGAGTTTGAGAAATCCCGCTACAGCACCTATGCAGCGCTGCTTCGG
GTCAAGCTGAAGGCAGGCAGTGAGGAGCTGGATGCAGTGGAGGCAGCACTGGCCCAGGCC
GGGAGCACAGAGGATGGACTCCCTCCTTCTCACTCCAGTCCCTCCCTGCAGCCCAAACCC
TCCAGCCAGCCCCGGGCTCAGCGTCACAGCTCAGAGCCTCGGCCAGGGGCAGGCAGTGGG
CGGCGGAAGCCCTGA
Protein Properties
Number of Residues 1024
Molecular Weight 109541.6
Theoretical pI 6.86
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>PH and SEC7 domain-containing protein 1
MAQGAMRFCSEGDCAISPPRCPRRWLPEGPVPQSPPASMYGSTGSLLRRVAGPGPRGREL
GRVTAPCTPLRGPPSPRVAPSPWAPSSPTGQPPPGAQSSVVIFRFVEKASVRPLNGLPAP
GGLSRSWDLGGVSPPRPTPALGPGSNRKLRLEASTSDPLPARGGSALPGSRNLVHGPPAP
PQVGADGLYSSLPNGLGGPPERLATLFGGPADTGFLNQGDTWSSPREVSSHAQRIARAKW
EFFYGSLDPPSSGAKPPEQAPPSPPGVGSRQGSGVAVGRAAKYSETDLDTVPLRCYRETD
IDEVLAEREEADSAIESQPSSEGPPGTAYPPAPRPGPLPGPHPSLGSGNEDEDDDEAGGE
EDVDDEVFEASEGARPGSRMPLKSPVPFLPGTSPSADGPDSFSCVFEAILESHRAKGTSY
TSLASLEALASPGPTQSPFFTFELPPQPPAPRPDPPAPAPLAPLEPDSGTSSAADGPWTQ
RGEEEEAEARAKLAPGREPPSPCHSEDSLGLGAAPLGSEPPLSQLVSDSDSELDSTERLA
LGSTDTLSNGQKADLEAAQRLAKRLYRLDGFRKADVARHLGKNNDFSKLVAGEYLKFFVF
TGMTLDQALRVFLKELALMGETQERERVLAHFSQRYFQCNPEALSSEDGAHTLTCALMLL
NTDLHGHNIGKRMTCGDFIGNLEGLNDGGDFPRELLKALYSSIKNEKLQWAIDEEELRRS
LSELADPNPKVIKRISGGSGSGSSPFLDLTPEPGAAVYKHGALVRKVHADPDCRKTPRGK
RGWKSFHGILKGMILYLQKEEYKPGKALSETELKNAISIHHALATRASDYSKRPHVFYLR
TADWRVFLFQAPSLEQMQSWITRINVVAAMFSAPPFPAAVSSQKKFSRPLLPSAATRLSQ
EEQVRTHEAKLKAMASELREHRAAQLGKKGRGKEAEEQRQKEAYLEFEKSRYSTYAALLR
VKLKAGSEELDAVEAALAQAGSTEDGLPPSHSSPSLQPKPSSQPRAQRHSSEPRPGAGSG
RRKP
GenBank ID Protein 56790299
UniProtKB/Swiss-Prot ID A5PKW4
UniProtKB/Swiss-Prot Entry Name PSD1_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_002779.3
GeneCard ID PSD
GenAtlas ID PSD
HGNC ID HGNC:9507
References
General References Not Available