| Identification |
|---|
| HMDB Protein ID
| CDBP05024 |
| Secondary Accession Numbers
| Not Available |
| Name
| Lambda-crystallin homolog |
| Description
| Not Available |
| Synonyms
|
- Gul3DH
- L-gulonate 3-dehydrogenase
|
| Gene Name
| CRYL1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in 3-hydroxyacyl-CoA dehydrogenase activity |
| Specific Function
| Not Available |
| GO Classification
|
| Biological Process |
| fatty acid metabolic process |
| Cellular Component |
| cytosol |
| Function |
| binding |
| nucleotide binding |
| catalytic activity |
| nad or nadh binding |
| oxidoreductase activity, acting on the ch-oh group of donors, nad or nadp as acceptor |
| nad binding |
| 3-hydroxyacyl-coa dehydrogenase activity |
| oxidoreductase activity, acting on ch-oh group of donors |
| oxidoreductase activity |
| Molecular Function |
| 3-hydroxyacyl-CoA dehydrogenase activity |
| L-gulonate 3-dehydrogenase activity |
| NAD+ binding |
| Process |
| cellular metabolic process |
| organic acid metabolic process |
| oxoacid metabolic process |
| carboxylic acid metabolic process |
| monocarboxylic acid metabolic process |
| fatty acid metabolic process |
| metabolic process |
|
| Cellular Location
|
- Cytoplasm
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Pentose and glucuronate interconversions | Not Available |  |
|
| Gene Properties |
|---|
| Chromosome Location
| 13 |
| Locus
| 13q12.11 |
| SNPs
| CRYL1 |
| Gene Sequence
|
>960 bp
ATGGCGTCCTCCGCGGCCGGCTGCGTGGTGATCGTTGGCAGTGGAGTCATTGGGCGAAGC
TGGGCCATGCTGTTTGCCAGTGGAGGCTTCCAGGTGAAACTCTATGACATTGAGCAACAG
CAGATAAGGAACGCCCTGGAAAACATCAGAAAGGAGATGAAGTTGCTGGAGCAGGCAGGT
TCTCTGAAAGGCTCCCTGAGTGTGGAAGAGCAGCTGTCACTCATCAGTGGTTGTCCCAAT
ATCCAAGAAGCAGTAGAGGGTGCCATGCACATTCAGGAATGTGTTCCAGAAGATCTAGAA
CTGAAGAAGAAGATTTTTGCTCAGTTAGATTCCATCATTGATGATCGAGTGATCTTAAGC
AGTTCCACTTCTTGTCTCATGCCTTCCAAGTTGTTTGCTGGCTTGGTCCATGTGAAGCAA
TGCATCGTGGCTCATCCTGTGAATCCGCCATACTACATCCCGCTGGTTGAGCTGGTCCCC
CACCCGGAGACGGCCCCTACGACAGTGGACAGAACCCACGCCCTGATGAAGAAGATTGGA
CAGTGCCCCATGCGAGTCCAGAAGGAGGTGGCCGGCTTCGTTCTGAACCGCCTGCAATAT
GCAATCATCAGCGAGGCCTGGCGGCTAGTGGAGGAAGGAATCGTGTCTCCTAGTGACCTG
GACCTTGTCATGTCAGAAGGGTTGGGCATGCGGTATGCATTCATTGGACCCCTGGAAACC
ATGCATCTCAATGCAGAAGGTATGTTAAGCTACTGCGACAGATACAGCGAAGGCATAAAA
CATGTCCTACAGACTTTTGGACCCATTCCAGAGTTTTCCAGGGCCACTGCTGAGAAGGTT
AACCAGGACATGTGCATGAAGGTCCCTGATGACCCGGAGCACTTAGCTGCCAGGAGGCAG
TGGAGGGACGAGTGCCTCATGAGACTCGCCAAGTTGAAGAGTCAAGTGCAGCCCCAGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 319 |
| Molecular Weight
| 35418.91 |
| Theoretical pI
| 6.175 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Lambda-crystallin homolog
MASSAAGCVVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAG
SLKGSLSVEEQLSLISGCPNIQEAVEGAMHIQECVPEDLELKKKIFAQLDSIIDDRVILS
SSTSCLMPSKLFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPETAPTTVDRTHALMKKIG
QCPMRVQKEVAGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSEGLGMRYAFIGPLET
MHLNAEGMLSYCDRYSEGIKHVLQTFGPIPEFSRATAEKVNQDMCMKVPDDPEHLAARRQ
WRDECLMRLAKLKSQVQPQ
|
| External Links |
|---|
| GenBank ID Protein
| 115430219 |
| UniProtKB/Swiss-Prot ID
| Q9Y2S2 |
| UniProtKB/Swiss-Prot Entry Name
| CRYL1_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| NM_015974.2 |
| GeneCard ID
| CRYL1 |
| GenAtlas ID
| CRYL1 |
| HGNC ID
| HGNC:18246 |
| References |
|---|
| General References
| Not Available |