| Identification |
|---|
| HMDB Protein ID
| CDBP05023 |
| Secondary Accession Numbers
| Not Available |
| Name
| Polyamine-modulated factor 1 |
| Description
| Not Available |
| Synonyms
|
- PMF-1
|
| Gene Name
| PMF1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in leucine zipper domain binding |
| Specific Function
| Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. May act as a cotranscription partner of NFE2L2 involved in regulation of polyamine-induced transcription of SSAT |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Nucleus
- Chromosome
- centromere
- kinetochore
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 1q12 |
| SNPs
| PMF1 |
| Gene Sequence
|
>618 bp
ATGGCCGAAGCAAGTAGCGCCAATCTAGGCAGCGGCTGTGAGGAAAAAAGGCATGAGGGG
TCGTCTTCGGAATCTGTGCCACCCGGCACTACCATTTCGAGGGTGAAGCTCCTCGACACC
ATGGTGGACACTTTTCTTCAGAAGCTGGTCGCCGCCGGCAGCTACCAGAGATTCACTGAC
TGCTATAAGTGCTTCTACCAGTTGCAGCCTGCGATGACACAGCAAATCTATGACAAGTTT
ATAGCTCAGTTGCAGACATCTATCCGGGAGGAAATCTCTGACATCAAAGAGGAGGGGAAC
CTAGAAGCTGTCTTGAATGCCTTGGATAAAATTGTGGAAGAAGGCAAAGTCCGCAAAGAG
CCAGCCTGGCGCCCCAGCGGGATCCCAGAGAAGGATCTGCACAGTGTTATGGCACCCTAC
TTCCTGCAGCAACGGGACACCCTGCGGCGCCATGTGCAGAAACAGGAGGCCGAGAACCAG
CAGCTGGCAGATGCCGTCCTGGCAGGGCGGAGGCAGGTGGAGGAGCTGCAGCTACAGGTC
CAGGCCCAGCAGCAGGCCTGGCAGGCTCTACACAGAGAACAGAGGGAGCTGGTTGCTGTG
CTGAGGGAGCCTGAGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 205 |
| Molecular Weight
| 23339.2 |
| Theoretical pI
| 5.18 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Polyamine-modulated factor 1
MAEASSANLGSGCEEKRHEGSSSESVPPGTTISRVKLLDTMVDTFLQKLVAAGSYQRFTD
CYKCFYQLQPAMTQQIYDKFIAQLQTSIREEISDIKEEGNLEAVLNALDKIVEEGKVRKE
PAWRPSGIPEKDLHSVMAPYFLQQRDTLRRHVQKQEAENQQLADAVLAGRRQVEELQLQV
QAQQQAWQALHREQRELVAVLREPE
|
| External Links |
|---|
| GenBank ID Protein
| 88900509 |
| UniProtKB/Swiss-Prot ID
| Q6P1K2 |
| UniProtKB/Swiss-Prot Entry Name
| PMF1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_007221.2 |
| GeneCard ID
| PMF1 |
| GenAtlas ID
| PMF1 |
| HGNC ID
| HGNC:9112 |
| References |
|---|
| General References
| Not Available |