Showing Protein Fatty acid-binding protein, intestinal (CDBP05015)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 5 compounds
Identification
HMDB Protein ID CDBP05015
Secondary Accession Numbers Not Available
Name Fatty acid-binding protein, intestinal
Description Not Available
Synonyms
  1. Fatty acid-binding protein 2
  2. I-FABP
  3. Intestinal-type fatty acid-binding protein
Gene Name FABP2
Protein Type Transporter
Biological Properties
General Function Involved in binding
Specific Function FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long- chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor
GO Classification
Function
binding
transporter activity
lipid binding
Process
establishment of localization
transport
Cellular Location
  1. Cytoplasm
Pathways
Gene Properties
Chromosome Location Chromosome:4
Locus 4q28-q31
SNPs FABP2
Gene Sequence 
>399 bp
ATGGCGTTTGACAGCACTTGGAAGGTAGACCGGAGTGAAAACTATGACAAGTTCATGGAA
AAAATGGGTGTTAATATAGTGAAAAGGAAGCTTGCAGCTCATGACAATTTGAAGCTGACA
ATTACACAAGAAGGAAATAAATTCACAGTCAAAGAATCAAGCGCTTTTCGAAACATTGAA
GTTGTTTTTGAACTTGGTGTCACCTTTAATTACAATCTAGCAGACGGAACTGAACTCAGG
GGGACCTGGAGCCTTGAGGGAAATAAACTTATTGGAAAATTCAAACGGACAGACAATGGA
AACGAACTGAATACTGTCCGAGAAATTATAGGTGATGAACTAGTCCAGACTTATGTATAT
GAAGGAGTAGAAGCCAAAAGGATCTTTAAAAAGGATTGA
Protein Properties
Number of Residues 132
Molecular Weight 15207.2
Theoretical pI 7.52
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Fatty acid-binding protein, intestinal
MAFDSTWKVDRSENYDKFMEKMGVNIVKRKLAAHDNLKLTITQEGNKFTVKESSAFRNIE
VVFELGVTFNYNLADGTELRGTWSLEGNKLIGKFKRTDNGNELNTVREIIGDELVQTYVY
EGVEAKRIFKKD
GenBank ID Protein 46854681
UniProtKB/Swiss-Prot ID P12104
UniProtKB/Swiss-Prot Entry Name FABPI_HUMAN
PDB IDs
GenBank Gene ID BC069466
GeneCard ID FABP2
GenAtlas ID FABP2
HGNC ID HGNC:3556
References
General References Not Available