| Identification |
|---|
| HMDB Protein ID
| CDBP05004 |
| Secondary Accession Numbers
| Not Available |
| Name
| Golgi resident protein GCP60 |
| Description
| Not Available |
| Synonyms
|
- Acyl-CoA-binding domain-containing protein 3
- GOCAP1
- GOLPH1
- Golgi complex-associated protein 1
- Golgi phosphoprotein 1
- PBR- and PKA-associated protein 7
- Peripheral benzodiazepine receptor-associated protein PAP7
|
| Gene Name
| ACBD3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in acyl-CoA binding |
| Specific Function
| Involved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport between the endoplasmic reticulum and Golgi. Involved in hormone-induced steroid biosynthesis in testicular Leydig cells |
| GO Classification
|
| Function |
| binding |
| fatty acid binding |
| acyl-coa binding |
| lipid binding |
|
| Cellular Location
|
- Mitochondrion
- Golgi apparatus membrane
- Peripheral membrane protein
- Cytoplasmic side
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 1q42.12 |
| SNPs
| ACBD3 |
| Gene Sequence
|
>1587 bp
ATGGCGGCGGTGCTGAACGCAGAGCGACTCGAGGTGTCCGTCGACGGCCTCACGCTCAGC
CCGGACCCGGAGGAGCGGCCTGGGGCGGAGGGCGCCCCGCTGCTGCCGCCACCGCTGCCA
CCGCCCTCGCCACCTGGATCCGGTCGCGGCCCGGGCGCCTCAGGGGAGCAGCCCGAGCCC
GGGGAGGCGGCGGCTGGGGGCGCGGCGGAGGAGGCGCGGCGGCTGGAGCAGCGCTGGGGT
TTCGGCCTGGAGGAGTTGTACGGCCTGGCACTGCGCTTCTTCAAAGAAAAAGATGGCAAA
GCATTTCATCCAACTTATGAAGAAAAATTGAAGCTTGTGGCACTGCATAAGCAAGTTCTT
ATGGGCCCATATAATCCAGACACTTGTCCTGAGGTTGGATTCTTTGATGTGTTGGGGAAT
GACAGGAGGAGAGAATGGGCAGCCCTGGGAAACATGTCTAAAGAGGATGCCATGGTGGAG
TTTGTCAAGCTCTTAAATAGGTGTTGCCATCTCTTTTCAACATATGTTGCGTCCCACAAA
ATAGAGAAGGAAGAGCAAGAAAAAAAAAGGAAGGAGGAAGAGGAGCGAAGGCGGCGTGAA
GAGGAAGAAAGAGAACGTCTGCAAAAGGAGGAAGAGAAACGTAGGAGAGAAGAAGAGGAA
AGGCTTCGACGGGAGGAAGAGGAAAGGAGACGGATAGAAGAAGAAAGGCTTCGGTTGGAG
CAGCAAAAGCAGCAGATAATGGCAGCTTTAAACTCCCAGACTGCCGTGCAGTTCCAGCAG
TATGCAGCCCAACAGTATCCAGGGAACTACGAACAGCAGCAAATTCTCATCCGCCAGTTG
CAGGAGCAACACTATCAGCAGTACATGCAGCAGTTGTATCAAGTCCAGCTTGCACAGCAA
CAGGCAGCATTACAGAAACAACAGGAAGTAGTAGTGGCTGGGTCTTCCTTGCCTACATCA
TCAAAAGTGAATGCAACTGTACCAAGTAATATGATGTCAGTTAATGGACAGGCCAAAACA
CACACTGACAGCTCCGAAAAAGAACTGGAACCAGAAGCTGCAGAAGAAGCCCTGGAGAAT
GGACCAAAAGAATCTCTTCCAGTAATAGCAGCTCCATCCATGTGGACACGACCTCAGATC
AAAGACTTCAAAGAGAAGATTCAGCAGGATGCAGATTCCGTGATTACAGTGGGCCGAGGA
GAAGTGGTCACTGTTCGAGTACCCACCCATGAAGAAGGATCATATCTCTTTTGGGAATTT
GCCACAGACAATTATGACATTGGGTTTGGGGTGTATTTTGAATGGACAGACTCTCCAAAC
ACTGCTGTCAGCGTGCATGTCAGTGAGTCCAGCGATGACGACGAGGAGGAAGAAGAAAAC
ATCGGTTGTGAAGAGAAAGCCAAAAAGAATGCCAACAAGCCTTTGCTGGATGAGATTGTG
CCTGTGTACCGACGGGACTGTCATGAGGAGGTGTATGCTGGCAGCCATCAATATCCAGGG
AGAGGAGTCTATCTCCTCAAGTTTGACAACTCCTACTCTTTGTGGCGGTCAAAATCAGTC
TACTACAGAGTCTATTATACTAGATAA
|
| Protein Properties |
|---|
| Number of Residues
| 528 |
| Molecular Weight
| 60593.0 |
| Theoretical pI
| 4.73 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Golgi resident protein GCP60
MAAVLNAERLEVSVDGLTLSPDPEERPGAEGAPLLPPPLPPPSPPGSGRGPGASGEQPEP
GEAAAGGAAEEARRLEQRWGFGLEELYGLALRFFKEKDGKAFHPTYEEKLKLVALHKQVL
MGPYNPDTCPEVGFFDVLGNDRRREWAALGNMSKEDAMVEFVKLLNRCCHLFSTYVASHK
IEKEEQEKKRKEEEERRRREEEERERLQKEEEKRRREEEERLRREEEERRRIEEERLRLE
QQKQQIMAALNSQTAVQFQQYAAQQYPGNYEQQQILIRQLQEQHYQQYMQQLYQVQLAQQ
QAALQKQQEVVVAGSSLPTSSKVNATVPSNMMSVNGQAKTHTDSSEKELEPEAAEEALEN
GPKESLPVIAAPSMWTRPQIKDFKEKIQQDADSVITVGRGEVVTVRVPTHEEGSYLFWEF
ATDNYDIGFGVYFEWTDSPNTAVSVHVSESSDDDEEEEENIGCEEKAKKNANKPLLDEIV
PVYRRDCHEEVYAGSHQYPGRGVYLLKFDNSYSLWRSKSVYYRVYYTR
|
| External Links |
|---|
| GenBank ID Protein
| 15799259 |
| UniProtKB/Swiss-Prot ID
| Q9H3P7 |
| UniProtKB/Swiss-Prot Entry Name
| GCP60_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AB043587 |
| GeneCard ID
| ACBD3 |
| GenAtlas ID
| ACBD3 |
| HGNC ID
| HGNC:15453 |
| References |
|---|
| General References
| Not Available |