| Identification |
|---|
| HMDB Protein ID
| CDBP05003 |
| Secondary Accession Numbers
| Not Available |
| Name
| Nucleoside diphosphate kinase |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| NME4 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in nucleoside diphosphate kinase activity |
| Specific Function
| ATP + nucleoside diphosphate = ADP + nucleoside triphosphate |
| GO Classification
|
| Function |
| transferase activity, transferring phosphorus-containing groups |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| adenyl ribonucleotide binding |
| atp binding |
| nucleoside diphosphate kinase activity |
| binding |
| catalytic activity |
| phosphotransferase activity, phosphate group as acceptor |
| transferase activity |
| Process |
| nitrogen compound metabolic process |
| cellular nitrogen compound metabolic process |
| nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
| nucleobase, nucleoside and nucleotide metabolic process |
| nucleoside phosphate metabolic process |
| nucleotide metabolic process |
| ctp biosynthetic process |
| pyrimidine nucleotide metabolic process |
| pyrimidine nucleoside triphosphate biosynthetic process |
| pyrimidine nucleotide biosynthetic process |
| pyrimidine ribonucleoside triphosphate biosynthetic process |
| utp biosynthetic process |
| purine nucleotide metabolic process |
| purine nucleotide biosynthetic process |
| purine nucleoside triphosphate biosynthetic process |
| purine ribonucleoside triphosphate biosynthetic process |
| gtp biosynthetic process |
| metabolic process |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 16p13.3 |
| SNPs
| NME4 |
| Gene Sequence
|
>354 bp
ATGAAGATGCTGCAGGCACCAGAGAGCGTCCTTGCCGAGCACTACCAGGACCTGCGGAGG
AAGCCCTTCTACCCTGCCCTCATCCGCTACATGAGCTCTGGGCCTGTGGTGGCCATGGTC
TGGGAAGGGTACAATGTCGTCCGCGCCTCGAGGGCCATGATTGGACACACCGACTCGGCT
GAGGCTGCCCCAGGAACCATAAGGGGTGACTTCAGCGTCCACATCAGCAGGAATGTCATC
CACGCCAGCGACTCCGTGGAGGGGGCCCAGCGGGAGATCCAGCTGTGGTTCCAGAGCAGT
GAGCTGGTGAGCTGGGCAGACGGGGGCCAGCACAGCAGCATCCACCCAGCCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 117 |
| Molecular Weight
| 12978.5 |
| Theoretical pI
| 6.8 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Nucleoside diphosphate kinase
MKMLQAPESVLAEHYQDLRRKPFYPALIRYMSSGPVVAMVWEGYNVVRASRAMIGHTDSA
EAAPGTIRGDFSVHISRNVIHASDSVEGAQREIQLWFQSSELVSWADGGQHSSIHPA
|
| External Links |
|---|
| GenBank ID Protein
| 123243692 |
| UniProtKB/Swiss-Prot ID
| A2IDD0 |
| UniProtKB/Swiss-Prot Entry Name
| A2IDD0_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| Z97634 |
| GeneCard ID
| NME4 |
| GenAtlas ID
| NME4 |
| HGNC ID
| HGNC:7852 |
| References |
|---|
| General References
| Not Available |