Cannabis Compound Database: Showing Protein Long-chain-fatty-acid--CoA ligase ACSBG1 (CDBP04993)

Identification Biological properties Gene properties Protein properties External links References XML Show 10 compounds

Identification

HMDB Protein ID

CDBP04993

Secondary Accession Numbers

Not Available

Name

Long-chain-fatty-acid--CoA ligase ACSBG1

Description

Not Available

Synonyms

Acyl-CoA synthetase bubblegum family member 1
Lipodisin
hBG1
hsBG
hsBGM
Lipidosin

Gene Name

ACSBG1

Protein Type

Enzyme

Biological Properties

General Function

Involved in catalytic activity

Specific Function

Mediates activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Able to activate long-chain fatty acids. Also able to activate very long-chain fatty acids; however, the relevance of such activity is unclear in vivo. Can activate diverse saturated, monosaturated and polyunsaturated fatty acids.

GO Classification

Biological Process
myelination
ovarian follicle atresia
very long-chain fatty acid metabolic process
response to glucocorticoid stimulus
Cellular Component
cytoplasm
endoplasmic reticulum
cytoplasmic membrane-bounded vesicle
Function
catalytic activity
Molecular Function
long-chain fatty acid-CoA ligase activity
very long-chain fatty acid-CoA ligase activity
ATP binding
Process
metabolic process

Cellular Location

Cytoplasm
Cytoplasmic vesicle
Microsome
Endoplasmic reticulum

Pathways

Name	SMPDB/Pathwhiz	KEGG
PPAR signaling pathway	Not Available
Adipocytokine signaling pathway	Not Available

Gene Properties

Chromosome Location

Locus

15q23-q24

SNPs

ACSBG1

Gene Sequence

>2175 bp
ATGCCACGCAATTCTGGAGCTGGATACGGCTGCCCACACGGGGACCCCAGCATGCTGGAC
AGCAGAGAGACCCCACAGGAGAGCCGGCAGGACATGATTGTGAGGACCACCCAAGAAAAA
TTGAAAACCAGCTCACTGACTGACAGGCAGCCACTCTCCAAAGAGTCCCTGAACCATGCT
CTCGAGCTCTCAGTGCCAGAGAAGGTGAATAATGCCCAGTGGGATGCTCCAGAGGAGGCG
CTGTGGACGACTCGGGCCGATGGGCGGGTGCGCCTGCGCATAGACCCCAGCTGCCCACAG
CTTCCCTACACTGTGCATCGGATGTTCTACGAGGCCCTGGATAAGTATGGGGACCTCATC
GCTTTGGGCTTCAAGCGCCAGGACAAGTGGGAACACATCTCCTACTCCCAATACTACCTG
CTCGCCCGCAGAGCCGCCAAGGGCTTCCTGAAGCTCGGCCTGAAGCAGGCCCACAGTGTG
GCCATCCTCGGCTTCAACTCCCCGGAGTGGTTCTTCTCGGCAGTGGGCACAGTATTTGCA
GGTGGCATCGTCACTGGCATCTACACCACCAGCTCCCCAGAGGCCTGCCAGTACATCGCT
TATGACTGCTGCGCCAATGTCATCATGGTCGACACGCAGAAGCAGCTGGAAAAGATCCTG
AAGATCTGGAAACAGTTGCCACATCTAAAGGCAGTCGTGATATATAAAGAACCTCCTCCA
AACAAGATGGCCAATGTGTACACGATGGAGGAATTCATGGAGCTGGGGAATGAAGTGCCT
GAGGAAGCCCTGGACGCCATCATTGACACCCAGCAGCCCAACCAGTGCTGTGTGCTAGTC
TACACTTCCGGCACCACTGGGAACCCCAAGGGCGTGATGCTGAGTCAAGACAATATCACG
TGGACGGCACGGTACGGCAGCCAGGCCGGTGACATCCGGCCGGCAGAAGTCCAGCAGGAG
GTGGTAGTCAGCTACCTGCCCCTCAGCCATATTGCCGCCCAGATCTACGACCTGTGGACA
GGCATCCAGTGGGGGGCCCAGGTTTGCTTTGCCGAACCCGACGCCCTGAAGGGGAGCCTG
GTGAACACGCTGCGGGAGGTGGAGCCCACATCACACATGGGGGTGCCCCGGGTATGGGAG
AAGATCATGGAGCGCATCCAGGAGGTGGCGGCTCAGTCTGGCTTCATCCGGCGAAAGATG
CTGCTGTGGGCCATGTCGGTGACCTTGGAGCAGAACCTCACCTGCCCCGGCAGCGACCTG
AAGCCCTTCACAACCAGACTGGCAGATTACCTGGTGCTAGCCAAGGTTCGCCAGGCACTG
GGATTTGCCAAGTGTCAAAAGAACTTCTATGGAGCGGCCCCCATGATGGCAGAGACACAG
CACTTCTTCCTGGGTCTCAACATCCGCTTGTATGCGGGCTACGGCCTCAGTGAGACCTCA
GGCCCCCACTTCATGTCCAGTCCCTACAACTACCGGCTGTACAGCTCAGGCAAGTTGGTG
CCCGGCTGTCGGGTGAAGCTGGTGAACCAGGACGCAGAGGGCATTGGCGAGATCTGCCTG
TGGGGCCGCACCATATTCATGGGCTACCTGAACATGGAGGACAAGACTTGTGAGGCCATC
GACGAGGAAGGCTGGCTGCACACGGGTGATGCTGGCCGCCTGGACGCCGATGGCTTCCTC
TACATCACTGGGCGCCTCAAAGAATTAATCATCACAGCTGGTGGGGAGAATGTGCCCCCT
GTGCCCATCGAGGAGGCCGTGAAGATGGAGCTGCCCATCATCAGCAACGCCATGCTCATT
GGGGACCAGAGGAAGTTCCTGTCCATGCTGCTCACCTTGAAGTGCACTCTGGACCCAGAC
ACCTCTGACCAGACTGATAATCTGACTGAACAAGCTATGGAGTTCTGCCAGAGGGTGGGC
AGCAGAGCCACCACAGTGTCCGAGATCATAGAGAAGAAGGATGAGGCCGTGTACCAGGCC
ATCGAAGAGGGGATCCGGAGGGTCAACATGAACGCGGCGGCCCGGCCCTACCACATCCAG
AAGTGGGCCATTCTCGAGAGAGACTTCTCCATTTCGGGTGGAGAGTTGGGTCCCACGATG
AAACTGAAACGGCTCACAGTTTTGGAGAAGTACAAAGGTATCATTGACTCCTTTTACCAA
GAGCAAAAAATGTAA

Protein Properties

Number of Residues

724

Molecular Weight

80878.065

Theoretical pI

5.92

Pfam Domain Function

AMP-binding (PF00501 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Long-chain-fatty-acid--CoA ligase ACSBG1
MPRNSGAGYGCPHGDPSMLDSRETPQESRQDMIVRTTQEKLKTSSLTDRQPLSKESLNHA
LELSVPEKVNNAQWDAPEEALWTTRADGRVRLRIDPSCPQLPYTVHRMFYEALDKYGDLI
ALGFKRQDKWEHISYSQYYLLARRAAKGFLKLGLKQAHSVAILGFNSPEWFFSAVGTVFA
GGIVTGIYTTSSPEACQYIAYDCCANVIMVDTQKQLEKILKIWKQLPHLKAVVIYKEPPP
NKMANVYTMEEFMELGNEVPEEALDAIIDTQQPNQCCVLVYTSGTTGNPKGVMLSQDNIT
WTARYGSQAGDIRPAEVQQEVVVSYLPLSHIAAQIYDLWTGIQWGAQVCFAEPDALKGSL
VNTLREVEPTSHMGVPRVWEKIMERIQEVAAQSGFIRRKMLLWAMSVTLEQNLTCPGSDL
KPFTTRLADYLVLAKVRQALGFAKCQKNFYGAAPMMAETQHFFLGLNIRLYAGYGLSETS
GPHFMSSPYNYRLYSSGKLVPGCRVKLVNQDAEGIGEICLWGRTIFMGYLNMEDKTCEAI
DEEGWLHTGDAGRLDADGFLYITGRLKELIITAGGENVPPVPIEEAVKMELPIISNAMLI
GDQRKFLSMLLTLKCTLDPDTSDQTDNLTEQAMEFCQRVGSRATTVSEIIEKKDEAVYQA
IEEGIRRVNMNAAARPYHIQKWAILERDFSISGGELGPTMKLKRLTVLEKYKGIIDSFYQ
EQKM

External Links

GenBank ID Protein

Not Available

UniProtKB/Swiss-Prot ID

Q96GR2

UniProtKB/Swiss-Prot Entry Name

ACBG1_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AF179481

GeneCard ID