| Identification |
|---|
| HMDB Protein ID
| CDBP04991 |
| Secondary Accession Numbers
| Not Available |
| Name
| Acyl-coenzyme A thioesterase 11 |
| Description
| Not Available |
| Synonyms
|
- Acyl-CoA thioester hydrolase 11
- Acyl-CoA thioesterase 11
- Adipose-associated thioesterase
- BFIT
- Brown fat-inducible thioesterase
|
| Gene Name
| ACOT11 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Lipid transport and metabolism |
| Specific Function
| Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Cytoplasm
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 1p32.3 |
| SNPs
| ACOT11 |
| Gene Sequence
|
>1824 bp
ATGATCCAGAATGTCGGAAATCACCTGCGACGGGGCTTGGCCTCTGTGTTCTCCAACCGC
ACATCCCGGAAGTCAGCCTTACGTGCGGGGAACGACAGTGCCATGGCAGACGGCGAGGGA
TACCGGAACCCCACGGAGGTGCAGATGAGCCAGCTGGTGCTGCCCTGCCACACCAACCAA
CGTGGTGAGCTGAGCGTCGGGCAGCTGCTCAAGTGGATTGACACCACGGCTTGCCTGTCC
GCGGAGAGGCACGCTGGCTGCCCCTGTGTCACAGCTTCCATGGATGACATCTATTTTGAG
CACACCATTAGTGTTGGACAAGTGGTGAATATCAAGGCCAAGGTGAACCGGGCCTTCAAC
TCCAGCATGGAGGTGGGCATCCAGGTGGCCTCGGAGGACCTGTGCTCTGAGAAGCAGTGG
AATGTGTGCAAGGCCTTGGCCACCTTCGTGGCCCGCCGAGAGATCACCAAGGTGAAGCTG
AAGCAGATCACGCCGCGGACAGAAGAGGAGAAGATGGAGCACAGTGTGGCGGCTGAGCGC
CGGCGCATGCGCCTTGTCTATGCAGACACCATCAAGGACCTCCTGGCCAACTGCGCCATT
CAGGGCGATCTGGAGAGCAGAGACTGTAGCCGCATGGTGCCGGCTGAGAAGACCCGTGTG
GAGAGTGTGGAGCTGGTCCTGCCTCCCCACGCCAATCACCAGGGCAACACCTTTGGGGGC
CAGATCATGGCCTGGATGGAGAATGTGGCCACCATTGCAGCCAGCCGGCTCTGCCGTGCC
CACCCTACGCTGAAGGCCATTGAAATGTTCCACTTCCGAGGCCCGTCCCAGGTCGGCGAC
CGTCTGGTGCTCAAAGCCATCGTGAACAATGCCTTCAAACATAGCATGGAGGTGGGCGTG
TGCGTGGAGGCCTATCGCCAGGAGGCTGAGACCCACCGGCGCCACATCAACAGTGCCTTT
ATGACCTTTGTGGTCCTGGACGCAGATGACCAGCCCCAGTTGCTGCCCTGGATTCGGCCC
CAGCCCGGCGATGGTGAGCGGCGGTACCGAGAGGCCAGTGCCAGAAAGAAGATCCGCCTG
GACAGGAAGTACATCGTGTCCTGTAAGCAGACAGAGGTGCCCCTCTCCGTCCCCTGGGAC
CCTAGCAACCAGGTGTACCTGAGCTACAATAACGTCTCCTCCTTGAAGATGCTTGTGGCC
AAGGACAACTGGGTGCTGTCCTCGGAGATCAGTCAGGTCCGCCTGTACACTCTGGAGGAT
GACAAGTTCCTCTCCTTCCACATGGAGATGGTGGTGCATGTGGATGCAGCCCAGGCCTTC
CTGCTGCTCTCGGACCTGCGTCAGAGGCCAGAGTGGGACAAGCACTACCGGAGCGTGGAG
CTAGTGCAGCAGGTAGACGAGGACGACGCCATCTACCACGTCACCAGCCCTGCCCTCGGA
GGTCACACAAAGCCCCAGGACTTCGTGATCCTGGCCTCGAGGCGGAAGCCTTGTGACAAT
GGGGACCCCTATGTCATCGCGCTGAGGTCGGTCACGCTGCCCACACACCGAGAGACGCCA
GAGTACAGACGCGGAGAGACCCTCTGCTCAGGCTTCTGCCTCTGGCGCGAGGGGGACCAG
CTGACCAAGTGCTGCTGGGTTAGGGTCTCCCTGACTGAGCTGGTCTCGGCAAGTGGCTTC
TATTCCTGGGGGCTCGAATCCAGGTCAAAGGGTCGCAGGAGCGACGGTTGGAATGGAAAA
CTAGCTGGAGGACACCTGAGTACTCTTAAAGCAATCCCCGTGGCCAAAATCAACAGCCGA
TTTGGATACCTTCAAGACACCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 607 |
| Molecular Weight
| 68491.6 |
| Theoretical pI
| 8.43 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Acyl-coenzyme A thioesterase 11
MIQNVGNHLRRGLASVFSNRTSRKSALRAGNDSAMADGEGYRNPTEVQMSQLVLPCHTNQ
RGELSVGQLLKWIDTTACLSAERHAGCPCVTASMDDIYFEHTISVGQVVNIKAKVNRAFN
SSMEVGIQVASEDLCSEKQWNVCKALATFVARREITKVKLKQITPRTEEEKMEHSVAAER
RRMRLVYADTIKDLLANCAIQGDLESRDCSRMVPAEKTRVESVELVLPPHANHQGNTFGG
QIMAWMENVATIAASRLCRAHPTLKAIEMFHFRGPSQVGDRLVLKAIVNNAFKHSMEVGV
CVEAYRQEAETHRRHINSAFMTFVVLDADDQPQLLPWIRPQPGDGERRYREASARKKIRL
DRKYIVSCKQTEVPLSVPWDPSNQVYLSYNNVSSLKMLVAKDNWVLSSEISQVRLYTLED
DKFLSFHMEMVVHVDAAQAFLLLSDLRQRPEWDKHYRSVELVQQVDEDDAIYHVTSPALG
GHTKPQDFVILASRRKPCDNGDPYVIALRSVTLPTHRETPEYRRGETLCSGFCLWREGDQ
LTKCCWVRVSLTELVSASGFYSWGLESRSKGRRSDGWNGKLAGGHLSTLKAIPVAKINSR
FGYLQDT
|
| External Links |
|---|
| GenBank ID Protein
| 22165355 |
| UniProtKB/Swiss-Prot ID
| Q8WXI4 |
| UniProtKB/Swiss-Prot Entry Name
| ACO11_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_015547.3 |
| GeneCard ID
| ACOT11 |
| GenAtlas ID
| ACOT11 |
| HGNC ID
| HGNC:18156 |
| References |
|---|
| General References
| Not Available |