| Identification |
|---|
| HMDB Protein ID
| CDBP04990 |
| Secondary Accession Numbers
| Not Available |
| Name
| Acyl-CoA synthetase family member 2, mitochondrial |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| ACSF2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in catalytic activity |
| Specific Function
| Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA. Has some preference toward medium-chain substrates. Plays a role in adipodyte differentiation |
| GO Classification
|
| Function |
| catalytic activity |
| Process |
| metabolic process |
|
| Cellular Location
|
- Mitochondrion (Potential)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 17q21.33 |
| SNPs
| ACSF2 |
| Gene Sequence
|
>1848 bp
ATGGCTGTCTACGTCGGGATGCTGCGCCTGGGGAGGCTGTGCGCCGGGAGCTCGGGGGTG
CTGGGGGCCCGGGCCGCCCTCTCTCGGAGTTGGCAGGAAGCCAGGTTGCAGGGTGTCCGC
TTCCTCAGTTCCAGAGAGGTGGATCGCATGGTCTCCACGCCCATCGGAGGCCTCAGCTAC
GTTCAGGGGTGCACCAAAAAGCATCTTAACAGCAAGACTGTGGGCCAGTGCCTGGAGACC
ACAGCACAGAGGGTCCCAGAACGAGAGGCCTTGGTCGTCCTCCATGAAGACGTCAGGTTG
ACCTTTGCCCAACTCAAGGAGGAGGTGGACAAAGCTGCTTCTGGCCTCCTGAGCATTGGC
CTCTGCAAAGGTGACCGGCTGGGCATGTGGGGACCTAACTCCTATGCATGGGTGCTCATG
CAGTTGGCCACCGCCCAGGCGGGCATCATTCTGGTGTCTGTGAACCCAGCCTACCAGGCT
ATGGAACTGGAGTATGTCCTCAAGAAGGTGGGCTGCAAGGCCCTTGTGTTCCCCAAGCAA
TTCAAGACCCAGCAATACTACAACGTCCTGAAGCAGATCTGTCCAGAAGTGGAGAATGCC
CAGCCAGGGGCCTTGAAGAGTCAGAGGCTCCCAGATCTGACCACAGTCATCTCGGTGGAT
GCCCCTTTGCCGGGGACCCTGCTCCTGGATGAAGTGGTGGCGGCTGGCAGCACACGGCAG
CATCTGGACCAGCTCCAATACAACCAGCAGTTCCTGTCCTGCCATGACCCCATCAACATC
CAGTTCACCTCGGGGACAACAGGCAGCCCCAAGGGGGCCACCCTCTCCCACTACAACATT
GTCAACAACTCCAACATTTTAGGAGAGCGCCTGAAACTGCATGAGAAGACACCAGAGCAG
TTGCGGATGATCCTGCCCAACCCCCTGTACCATTGCCTGGGTTCCGTGGCAGGCACAATG
ATGTGTCTGATGTACGGTGCCACCCTCATCCTGGCCTCTCCCATCTTCAATGGCAAGAAG
GCACTGGAGGCCATCAGCAGAGAGAGAGGCACCTTCCTGTATGGTACCCCCACGATGTTC
GTGGACATTCTGAACCAGCCAGACTTCTCCAGTTATGACATCTCGACCATGTGTGGAGGT
GTCATTGCTGGGTCCCCTGCACCTCCAGAGTTGATCCGAGCCATCATCAACAAGATAAAT
ATGAAGGACCTGGTGGTTGCTTATGGAACCACAGAGAACAGTCCCGTGACATTCGCGCAC
TTCCCTGAGGACACTGTGGAGCAGAAGGCAGAAAGCGTGGGCAGAATTATGCCTCACACG
GAGGCCCGGATCATGAACATGGAGGCAGGGACGCTGGCAAAGCTGAACACGCCCGGGGAG
CTGTGCATCCGAGGGTACTGCGTCATGCTGGGCTACTGGGGTGAGCCTCAGAAGACAGAG
GAAGCAGTGGATCAGGACAAGTGGTATTGGACAGGAGATGTCGCCACAATGAATGAGCAG
GGCTTCTGCAAGATCGTGGGCCGCTCTAAGGATATGATCATCCGGGGTGGTGAGAACATC
TACCCCGCAGAGCTCGAGGACTTCTTTCACACACACCCGAAGGTGCAGGAAGTGCAGGTG
GTGGGAGTGAAGGACGATCGGATGGGGGAAGAGATTTGTGCCTGCATTCGGCTGAAGGAC
GGGGAGGAGACCACGGTGGAGGAGATAAAAGCTTTCTGCAAAGGGAAGATCTCTCACTTC
AAGATTCCGAAGTACATCGTGTTTGTCACAAACTACCCCCTCACCATTTCAGGAAAGATC
CAGAAATTCAAACTTCGAGAGCAGATGGAACGACATCTAAATCTGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 615 |
| Molecular Weight
| 68124.4 |
| Theoretical pI
| 7.6 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Acyl-CoA synthetase family member 2, mitochondrial
MAVYVGMLRLGRLCAGSSGVLGARAALSRSWQEARLQGVRFLSSREVDRMVSTPIGGLSY
VQGCTKKHLNSKTVGQCLETTAQRVPEREALVVLHEDVRLTFAQLKEEVDKAASGLLSIG
LCKGDRLGMWGPNSYAWVLMQLATAQAGIILVSVNPAYQAMELEYVLKKVGCKALVFPKQ
FKTQQYYNVLKQICPEVENAQPGALKSQRLPDLTTVISVDAPLPGTLLLDEVVAAGSTRQ
HLDQLQYNQQFLSCHDPINIQFTSGTTGSPKGATLSHYNIVNNSNILGERLKLHEKTPEQ
LRMILPNPLYHCLGSVAGTMMCLMYGATLILASPIFNGKKALEAISRERGTFLYGTPTMF
VDILNQPDFSSYDISTMCGGVIAGSPAPPELIRAIINKINMKDLVVAYGTTENSPVTFAH
FPEDTVEQKAESVGRIMPHTEARIMNMEAGTLAKLNTPGELCIRGYCVMLGYWGEPQKTE
EAVDQDKWYWTGDVATMNEQGFCKIVGRSKDMIIRGGENIYPAELEDFFHTHPKVQEVQV
VGVKDDRMGEEICACIRLKDGEETTVEEIKAFCKGKISHFKIPKYIVFVTNYPLTISGKI
QKFKLREQMERHLNL
|
| External Links |
|---|
| GenBank ID Protein
| 10436885 |
| UniProtKB/Swiss-Prot ID
| Q96CM8 |
| UniProtKB/Swiss-Prot Entry Name
| ACSF2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AK024573 |
| GeneCard ID
| ACSF2 |
| GenAtlas ID
| ACSF2 |
| HGNC ID
| HGNC:26101 |
| References |
|---|
| General References
| Not Available |