| Identification |
|---|
| HMDB Protein ID
| CDBP04966 |
| Secondary Accession Numbers
| Not Available |
| Name
| Oxysterol-binding protein-related protein 2 |
| Description
| Not Available |
| Synonyms
|
- ORP-2
- OSBP-related protein 2
|
| Gene Name
| OSBPL2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in steroid metabolic process |
| Specific Function
| Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3- phosphate |
| GO Classification
|
| Process |
| metabolic process |
| primary metabolic process |
| lipid metabolic process |
| steroid metabolic process |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:2 |
| Locus
| 20q13.3 |
| SNPs
| OSBPL2 |
| Gene Sequence
|
>1443 bp
ATGAACGGAGAGGAAGAATTCTTTGATGCCGTCACAGGCTTTGATTCTGATAACTCTTCT
GGGGAATTTTCAGAGGCAAATCAGAAAGTCACGGGAATGATTGACTTAGACACCAGCAAA
AATAATAGGATTGGGAAAACTGGGGAGAGGCCCTCTCAAGAGAACGGAATTCAGAAACAC
AGGACATCGCTGCCGGCTCCCATGTTCAGCAGAAGCGACTTCAGCGTGTGGACCATCCTG
AAGAAGTGTGTTGGCCTGGAGCTGTCCAAGATCACGATGCCAATCGCCTTCAACGAGCCT
CTGAGCTTCTTGCAGCGGATCACGGAGTACATGGAGCACGTGTACCTCATCCACAGGGCC
TCCTGCCAGCCCCAGCCCCTGGAGAGGATGCAGTCTGTGGCTGCTTTTGCTGTTTCGGCT
GTGGCTTCCCAGTGGGAGAGGACCGGCAAACCATTTAATCCACTCTTGGGAGAAACGTAT
GAATTAATCAGGGAAGATTTAGGATTCAGATTTATATCGGAACAGGTCAGTCACCACCCC
CCCATCAGTGCGTTCCACTCGGAAGGTCTCAACCATGACTTCCTGTTCCATGGCTCCATC
TACCCCAAGCTCAAGTTCTGGGGCAAAAGCGTGGAGGCGGAGCCCCGAGGCACCATCACC
CTGGAGCTGCTCAAACATAATGAAGCCTACACCTGGACCAACCCCACCTGCTGCGTCCAC
AACGTCATCATCGGGAAGCTGTGGATAGAGCAGTATGGGACAGTGGAGATTTTAAACCAC
AGAACTGGACATAAGTGTGTGCTTCACTTTAAACCGTGTGGATTATTTGGAAAAGAACTT
CACAAGGTGGAAGGACACATTCAAGACAAAAACAAAAAGAAGCTCTTTATGATCTATGGC
AAATGGACGGAATGTTTGTGGGGCATAGATCCTGTTTCGTATGAATCCTTCAAGAAGCAG
GAGAGGAGAGGTGACCACCTGAGAAAGGCCAAGCTGGATGAAGACTCCGGGAAGGCTGAC
AGCGACGTGGCTGACGACGTGCCTGTGGCCCAGGAGACCGTGCAGGTCATTCCTGGCAGC
AAGCTGCTCTGGAGGATCAACACCCGGCCCCCCAACTCTGCCCAGATGTATAATTTCACC
AGTTTCACTGTGAGCCTCAACGAGCTGGAGACAGGCATGGAGAAGACCCTGCCACCCACG
GACTGCCGCCTGCGCCCTGACATCCGCGGCATGGAGAATGGCAACATGGATCTGGCCAGC
CAGGAGAAGGAGCGGCTGGAGGAGAAGCAGAGAGAAGCACGGAGGGAGCGGGCCAAGGAG
GAGGCAGAGTGGCAGACGAGGTGGTTCTACCCAGGCAATAACCCCTACACTGGGACCCCC
GACTGGTTGTATGCAGGGGATTACTTTGAGCGGAATTTCTCCGACTGCCCAGATATCTAC
TGA
|
| Protein Properties |
|---|
| Number of Residues
| 480 |
| Molecular Weight
| 55200.9 |
| Theoretical pI
| 6.31 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Oxysterol-binding protein-related protein 2
MNGEEEFFDAVTGFDSDNSSGEFSEANQKVTGMIDLDTSKNNRIGKTGERPSQENGIQKH
RTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRA
SCQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIREDLGFRFISEQVSHHP
PISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVH
NVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLFMIYG
KWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPGS
KLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLAS
QEKERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFERNFSDCPDIY
|
| External Links |
|---|
| GenBank ID Protein
| 21450853 |
| UniProtKB/Swiss-Prot ID
| Q9H1P3 |
| UniProtKB/Swiss-Prot Entry Name
| OSBL2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_144498.1 |
| GeneCard ID
| OSBPL2 |
| GenAtlas ID
| OSBPL2 |
| HGNC ID
| HGNC:15761 |
| References |
|---|
| General References
| Not Available |