| Identification |
|---|
| HMDB Protein ID
| CDBP04917 |
| Secondary Accession Numbers
| Not Available |
| Name
| Zinc finger protein ZIC 3 |
| Description
| Not Available |
| Synonyms
|
- Zinc finger protein of the cerebellum 3
|
| Gene Name
| ZIC3 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in zinc ion binding |
| Specific Function
| Probably functions as a transcription factor in the earliest stages of the left-right (LR) body axis formation |
| GO Classification
|
| Component |
| cell part |
| intracellular |
| Function |
| nucleic acid binding |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| transition metal ion binding |
| zinc ion binding |
|
| Cellular Location
|
- Nucleus
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| ZIC3 |
| Gene Sequence
|
>1404 bp
ATGACGATGCTCCTGGACGGAGGCCCGCAGTTCCCTGGGCTGGGAGTGGGCAGCTTCGGC
GCGCCGCGCCACCACGAGATGCCCAACCGTGAGCCGGCAGGCATGGGGCTGAATCCCTTC
GGGGACTCAACCCACGCCGCCGCCGCCGCCGCCGCCGCCGCTGCCTTCAAGCTGAGCCCT
GCCGCGGCGCACGATCTATCTTCAGGCCAGAGCTCGGCTTTCACGCCGCAGGGTTCGGGC
TACGCCAACGCCCTGGGCCACCATCACCACCACCATCACCATCATCACCACACCAGCCAG
GTGCCCAGCTACGGTGGCGCTGCCTCTGCCGCCTTCAACTCAACGCGCGAGTTTCTGTTC
CGCCAGCGCAGCTCCGGGCTCAGTGAGGCGGCCTCGGGTGGCGGGCAGCACGGGCTCTTC
GCCGGCTCGGCGAGCAGCCTGCATGCTCCAGCTGGCATCCCCGAGCCCCCTAGCTACTTG
CTGTTTCCCGGGCTGCATGAGCAGGGCGCTGGGCACCCGTCTCCCACAGGGCACGTGGAC
AACAACCAGGTCCACCTGGGGCTGCGTGGGGAGCTGTTCGGCCGTGCTGACCCATACCGC
CCAGTGGCCAGCCCGCGCACGGACCCATACGCGGCCGGCGCTCAGTTTCCTAACTACAGC
CCCATGAACATGAACATGGGAGTGAACGTGGCGGCCCACCACGGGCCCGGCGCCTTCTTC
CGTTATATGCGGCAGCCTATCAAGCAGGAGCTGTCGTGCAAGTGGATCGACGAGGCTCAG
CTGAGCCGGCCCAAGAAGAGCTGCGACCGGACCTTCAGCACCATGCATGAGCTGGTGACA
CATGTCACCATGGAGCATGTGGGGGGCCCGGAGCAGAACAACCACGTCTGCTACTGGGAG
GAGTGCCCCCGGGAGGGCAAGTCTTTCAAGGCGAAGTACAAACTGGTCAACCACATCCGA
GTGCACACGGGCGAGAAGCCCTTCCCATGCCCCTTCCCGGGCTGCGGGAAGATCTTTGCC
CGTTCTGAGAACCTCAAGATCCACAAGAGGACCCACACAGGTGAGAAACCTTTCAAATGT
GAATTTGAAGGCTGTGACAGACGCTTTGCCAACAGCAGCGACCGTAAGAAGCACATGCAT
GTGCATACCTCGGACAAGCCCTATATCTGCAAAGTGTGCGACAAGTCCTACACGCACCCG
AGCTCCCTGCGCAAACACATGAAGGTTCATGAATCTCAAGGGTCAGATTCCTCCCCTGCT
GCCAGTTCAGGCTATGAATCTTCCACTCCACCCGCTATAGCTTCTGCAAACAGTAAAGAT
ACCACTAAAACCCCTTCTGCAGTTCAAACTAGCACCAGCCACAACCCTGGACTTCCTCCT
AATTTTAACGAATGGTACGTCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 467 |
| Molecular Weight
| 50569.1 |
| Theoretical pI
| 8.81 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Zinc finger protein ZIC 3
MTMLLDGGPQFPGLGVGSFGAPRHHEMPNREPAGMGLNPFGDSTHAAAAAAAAAAFKLSP
AAAHDLSSGQSSAFTPQGSGYANALGHHHHHHHHHHHTSQVPSYGGAASAAFNSTREFLF
RQRSSGLSEAASGGGQHGLFAGSASSLHAPAGIPEPPSYLLFPGLHEQGAGHPSPTGHVD
NNQVHLGLRGELFGRADPYRPVASPRTDPYAAGAQFPNYSPMNMNMGVNVAAHHGPGAFF
RYMRQPIKQELSCKWIDEAQLSRPKKSCDRTFSTMHELVTHVTMEHVGGPEQNNHVCYWE
ECPREGKSFKAKYKLVNHIRVHTGEKPFPCPFPGCGKIFARSENLKIHKRTHTGEKPFKC
EFEGCDRRFANSSDRKKHMHVHTSDKPYICKVCDKSYTHPSSLRKHMKVHESQGSDSSPA
ASSGYESSTPPAIASANSKDTTKTPSAVQTSTSHNPGLPPNFNEWYV
|
| External Links |
|---|
| GenBank ID Protein
| 2957266 |
| UniProtKB/Swiss-Prot ID
| O60481 |
| UniProtKB/Swiss-Prot Entry Name
| ZIC3_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF028706 |
| GeneCard ID
| ZIC3 |
| GenAtlas ID
| ZIC3 |
| HGNC ID
| HGNC:12874 |
| References |
|---|
| General References
| Not Available |