| Identification |
|---|
| HMDB Protein ID
| CDBP04862 |
| Secondary Accession Numbers
| Not Available |
| Name
| 5-hydroxytryptamine receptor 5A |
| Description
| Not Available |
| Synonyms
|
- 5-HT-5
- 5-HT-5A
- 5-HT5A
- Serotonin receptor 5A
|
| Gene Name
| HTR5A |
| Protein Type
| Receptor |
| Biological Properties |
|---|
| General Function
| Involved in G-protein coupled receptor protein signaling pathway |
| Specific Function
| This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins |
| GO Classification
|
| Component |
| membrane part |
| intrinsic to membrane |
| integral to membrane |
| cell part |
| Process |
| signaling |
| signaling pathway |
| cell surface receptor linked signaling pathway |
| g-protein coupled receptor protein signaling pathway |
|
| Cellular Location
|
- Cell membrane
- Multi-pass membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:7 |
| Locus
| 7q36.1 |
| SNPs
| HTR5A |
| Gene Sequence
|
>1074 bp
ATGGATTTACCAGTGAACCTAACCTCCTTTTCCCTCTCCACCCCCTCCCCTTTGGAGACC
AACCACAGCCTCGGCAAAGACGACCTGCGCCCCAGCTCGCCCCTGCTCTCGGTCTTCGGA
GTGCTTATTCTCACCTTGCTGGGCTTTCTGGTGGCGGCGACGTTCGCCTGGAACCTGCTG
GTGCTGGCGACCATCCTCCGTGTACGCACCTTCCACCGCGTGCCCCACAACCTGGTGGCA
TCCATGGCCGTCTCGGATGTCCTGGTGGCCGCGCTGGTCATGCCGCTGAGCCTGGTGCAC
GAGCTGTCCGGGCGCCGCTGGCAGCTAGGTCGGAGGCTGTGCCAGCTTTGGATCGCGTGC
GACGTGCTTTGCTGCACGGCCAGCATCTGGAACGTGACGGCCATAGCCCTGGACCGCTAC
TGGTCCATCACGCGCCACATGGAATACACGCTCCGCACCCGCAAGTGCGTCTCCAACGTC
ATGATCGCGCTCACCTGGGCACTCTCCGCTGTCATCTCTCTGGCCCCGCTGCTTTTTGGC
TGGGGAGAGACGTACTCTGAGGGCAGCGAGGAGTGCCAGGTAAGCCGCGAGCCTTCCTAC
GCCGTGTTCTCCACCGTAGGCGCCTTCTACCTGCCGCTCTGTGTGGTGCTCTTCGTGTAC
TGGAAGATCTACAAGGCTGCCAAGTTCCGCGTGGGCTCCAGGAAGACCAATAGCGTCTCA
CCCATATCCGAAGCTGTGGAGGTGAAGGACTCTGCCAAACAGCCCCAGATGGTGTTCACG
GTCCGCCACGCCACCGTCACCTTCCAGCCAGAAGGGGACACGTGGCGGGAGCAGAAGGAG
CAGCGGGCCGCCCTCATGGTGGGCATCCTCATTGGCGTGTTCGTGCTCTGCTGGATCCCC
TTCTTTCTCACCGAGCTCATCAGTCCCCTCTGCTCCTGTGACATCCCCGCCATCTGGAAA
AGCATCTTCCTGTGGCTTGGCTACTCCAACTCCTTCTTTAACCCCCTGATCTATACGGCT
TTCAACAAGAACTACAACAGCGCCTTCAAGAACTTCTTTTCTAGGCAACACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 357 |
| Molecular Weight
| 40254.7 |
| Theoretical pI
| 8.82 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
- ["41-63", "79-99", "116-137", "159-181", "199-219", "283-303", "321-341"]
|
| Protein Sequence
|
>5-hydroxytryptamine receptor 5A
MDLPVNLTSFSLSTPSPLETNHSLGKDDLRPSSPLLSVFGVLILTLLGFLVAATFAWNLL
VLATILRVRTFHRVPHNLVASMAVSDVLVAALVMPLSLVHELSGRRWQLGRRLCQLWIAC
DVLCCTASIWNVTAIALDRYWSITRHMEYTLRTRKCVSNVMIALTWALSAVISLAPLLFG
WGETYSEGSEECQVSREPSYAVFSTVGAFYLPLCVVLFVYWKIYKAAKFRVGSRKTNSVS
PISEAVEVKDSAKQPQMVFTVRHATVTFQPEGDTWREQKEQRAALMVGILIGVFVLCWIP
FFLTELISPLCSCDIPAIWKSIFLWLGYSNSFFNPLIYTAFNKNYNSAFKNFFSRQH
|
| External Links |
|---|
| GenBank ID Protein
| 20379144 |
| UniProtKB/Swiss-Prot ID
| P47898 |
| UniProtKB/Swiss-Prot Entry Name
| 5HT5A_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF498985 |
| GeneCard ID
| HTR5A |
| GenAtlas ID
| HTR5A |
| HGNC ID
| HGNC:5300 |
| References |
|---|
| General References
| Not Available |