| Identification |
|---|
| HMDB Protein ID
| CDBP04856 |
| Secondary Accession Numbers
| Not Available |
| Name
| Mitochondrial folate transporter/carrier |
| Description
| Not Available |
| Synonyms
|
- Solute carrier family 25 member 32
|
| Gene Name
| SLC25A32 |
| Protein Type
| Transporter |
| Biological Properties |
|---|
| General Function
| Involved in transporter activity |
| Specific Function
| Transports folate across the inner membranes of mitochondria.
|
| GO Classification
|
| Biological Process |
| mitochondrial transport |
| folic acid metabolic process |
| Cellular Component |
| integral to membrane |
| mitochondrial inner membrane |
| Component |
| membrane |
| cell part |
| organelle membrane |
| organelle inner membrane |
| mitochondrial inner membrane |
| Function |
| binding |
| transporter activity |
| Molecular Function |
| folic acid transporter activity |
| Process |
| establishment of localization |
| transport |
| transmembrane transport |
|
| Cellular Location
|
- Mitochondrion inner membrane
- Multi-pass membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 8 |
| Locus
| 8q22.3 |
| SNPs
| SLC25A32 |
| Gene Sequence
|
>948 bp
ATGACGGGCCAGGGCCAGTCGGCGTCCGGGTCGTCGGCGTGGAGCACGGTATTCCGCCAC
GTCCGGTATGAGAACCTGATAGCGGGCGTGAGCGGCGGCGTCTTATCCAACCTTGCGCTG
CATCCGCTCGACCTCGTGAAGATCCGCTTCGCCGTGAGTGATGGATTGGAACTGAGACCG
AAATATAATGGAATTTTACATTGCTTGACTACCATTTGGAAACTTGATGGACTACGGGGA
CTTTATCAAGGAGTAACCCCAAATATATGGGGTGCAGGTTTATCCTGGGGACTCTACTTT
TTCTTTTACAATGCCATCAAGTCATATAAAACAGAAGGAAGAGCTGAACATTTAGAGGCA
ACAGAATACCTTGTCTCAGCTGCTGAAGCTGGAGCCATGACCCTCTGCATTACAAACCCA
TTATGGGTAACAAAAACTCGCCTTATGTTACAGTATGATGCTGTTGTTAACTCCCCACAC
CGACAATATAAAGGAATGTTTGATACACTTGTGAAAATATATAAGTATGAAGGTGTGCGT
GGATTATATAAGGGATTTGTTCCTGGGCTGTTTGGAACATCGCATGGTGCCCTTCAGTTT
ATGGCATATGAATTGCTGAAGTTGAAGTACAACCAGCATATCAATAGATTACCAGAAGCC
CAGTTGAGCACAGTAGAATATATATCTGTTGCAGCACTATCCAAAATATTTGCTGTCGCA
GCAACATACCCATATCAAGTCGTAAGAGCTCGTCTTCAGGATCAACACATGTTTTACAGT
GGTGTAATAGATGTAATCACAAAGACATGGAGGAAAGAAGGCGTCGGTGGATTTTACAAG
GGAATTGCTCCTAATTTGATTAGAGTGACTCCAGCCTGCTGTATTACCTTTGTGGTATAT
GAAAACGTCTCACATTTTTTACTTGACCTTAGAGAAAAGAGAAAGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 315 |
| Molecular Weight
| 35406.83 |
| Theoretical pI
| 9.453 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Mitochondrial folate transporter/carrier
MTGQGQSASGSSAWSTVFRHVRYENLIAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRP
KYNGILHCLTTIWKLDGLRGLYQGVTPNIWGAGLSWGLYFFFYNAIKSYKTEGRAERLEA
TEYLVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVR
GLYKGFVPGLFGTSHGALQFMAYELLKLKYNQHINRLPEAQLSTVEYISVAALSKIFAVA
ATYPYQVVRARLQDQHMFYSGVIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVVY
ENVSHFLLDLREKRK
|
| External Links |
|---|
| GenBank ID Protein
| 11545417 |
| UniProtKB/Swiss-Prot ID
| Q9H2D1 |
| UniProtKB/Swiss-Prot Entry Name
| MFTC_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF283645 |
| GeneCard ID
| SLC25A32 |
| GenAtlas ID
| SLC25A32 |
| HGNC ID
| HGNC:29683 |
| References |
|---|
| General References
| Not Available |