| Identification |
|---|
| HMDB Protein ID
| CDBP04855 |
| Secondary Accession Numbers
| Not Available |
| Name
| Folate receptor beta |
| Description
| Not Available |
| Synonyms
|
- FBP
- FR-beta
- Folate receptor 2
- Folate receptor, fetal/placental
- Placental folate-binding protein
|
| Gene Name
| FOLR2 |
| Protein Type
| Receptor |
| Biological Properties |
|---|
| General Function
| Involved in folic acid binding |
| Specific Function
| Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Cell membrane
- Lipid-anchor
- GPI-anchor
- Secreted (Probable)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 11q13.3-q13.5 |
| SNPs
| FOLR2 |
| Gene Sequence
|
>768 bp
ATGGTCTGGAAATGGATGCCACTTCTGCTGCTTCTGGTCTGTGTAGCCACCATGTGCAGT
GCCCAGGACAGGACTGATCTCCTCAATGTCTGTATGGATGCCAAGCACCACAAGACAAAG
CCAGGTCCTGAGGACAAGCTGCATGACCAATGCAGTCCCTGGAAGAAGAATGCCTGCTGC
ACAGCCAGCACCAGCCAGGAGCTGCACAAGGACACCTCCCGCCTGTACAACTTTAACTGG
GACCACTGCGGCAAGATGGAGCCCGCCTGCAAGCGCCACTTCATCCAGGACACCTGTCTC
TATGAGTGCTCACCCAACCTGGGGCCCTGGATCCAGCAGGTGAATCAGACGTGGCGAAAA
GAACGCTTCCTGGATGTGCCCTTATGCAAAGAGGACTGTCAGCGCTGGTGGGAGGATTGT
CACACCTCCCACACGTGCAAGAGCAACTGGCACAGAGGATGGGACTGGACCTCAGGAGTT
AACAAGTGCCCAGCTGGGGCTCTCTGCCGCACCTTTGAGTCCTACTTCCCCACTCCAGCT
GCCCTTTGTGAAGGCCTCTGGAGTCACTCATACAAGGTCAGCAACTACAGCCGAGGGAGC
GGCCGCTGCATCCAGATGTGGTTTGATTCAGCCCAGGGCAACCCCAACGAGGAAGTGGCG
AGGTTCTATGCTGCAGCCATGCATGTGAATGCTGGTGAGATGCTTCATGGGACTGGGGGT
CTCCTGCTCAGTCTGGCCCTGATGCTGCAACTCTGGCTCCTTGGCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 255 |
| Molecular Weight
| 29279.3 |
| Theoretical pI
| 7.56 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Folate receptor beta
MVWKWMPLLLLLVCVATMCSAQDRTDLLNVCMDAKHHKTKPGPEDKLHDQCSPWKKNACC
TASTSQELHKDTSRLYNFNWDHCGKMEPACKRHFIQDTCLYECSPNLGPWIQQVNQSWRK
ERFLDVPLCKEDCQRWWEDCHTSHTCKSNWHRGWDWTSGVNKCPAGALCRTFESYFPTPA
ALCEGLWSHSYKVSNYSRGSGRCIQMWFDSAQGNPNEEVARFYAAAMHVNAGEMLHGTGG
LLLSLALMLQLWLLG
|
| External Links |
|---|
| GenBank ID Protein
| 182414 |
| UniProtKB/Swiss-Prot ID
| P14207 |
| UniProtKB/Swiss-Prot Entry Name
| FOLR2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| J02876 |
| GeneCard ID
| FOLR2 |
| GenAtlas ID
| FOLR2 |
| HGNC ID
| HGNC:3793 |
| References |
|---|
| General References
| Not Available |