Cannabis Compound Database: Showing Protein Potassium voltage-gated channel subfamily C member 4 (CDBP04853)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP04853

Secondary Accession Numbers

Not Available

Name

Potassium voltage-gated channel subfamily C member 4

Description

Not Available

Synonyms

KSHIIIC
Voltage-gated potassium channel subunit Kv3.4

Gene Name

KCNC4

Protein Type

Transporter

Biological Properties

General Function

Involved in protein binding

Specific Function

This protein mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient

GO Classification

Component
macromolecular complex
intrinsic to membrane
protein complex
integral to membrane
membrane
cell part
membrane part
ion channel complex
cation channel complex
potassium channel complex
voltage-gated potassium channel complex
Function
binding
protein binding
transmembrane transporter activity
substrate-specific transmembrane transporter activity
ion transmembrane transporter activity
transporter activity
ion channel activity
cation channel activity
potassium channel activity
voltage-gated potassium channel activity
Process
transmembrane transport
monovalent inorganic cation transport
potassium ion transport
ion transport
cation transport
establishment of localization
transport

Cellular Location

Membrane
Multi-pass membrane protein

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:1

Locus

1p21

SNPs

KCNC4

Gene Sequence

>1908 bp
ATGATCAGCTCGGTGTGTGTCTCCTCCTACCGCGGGCGCAAGTCGGGGAACAAGCCTCCG
TCCAAAACATGTCTGAAGGAGGAGATGGCCAAGGGCGAGGCGTCGGAGAAGATCATCATC
AACGTGGGCGGCACGCGACATGAGACCTACCGCAGCACCCTGCGCACCCTACCGGGAACC
CGCCTCGCCTGGCTGGCCGACCCCGACGGCGGGGGCCGGCCCGAGACCGATGGCGGCGGT
GTGGGTAGCAGCGGCAGCAGCGGCGGCGGGGGCTGCGAGTTCTTCTTCGACAGGCACCCG
GGCGTCTTCGCCTACGTGCTCAACTACTACCGCACCGGCAAGCTGCACTGCCCCGCGGAC
GTGTGCGGGCCGCTCTTCGAAGAGGAGCTCACCTTCTGGGGCATCGACGAGACCGACGTG
GAACCCTGCTGCTGGATGACCTACCGGCAGCACCGCGACGCCGAGGAGGCGCTCGACATC
TTCGAGAGCCCGGACGGAGGCGGCAGCGGCGCGGGGCCCAGCGACGAGGCCGGCGACGAT
GAGCGGGAGCTGGCCCTGCAGCGACTGGGCCCCCACGAGGGAGGCGCGGGCCATGGCGCC
GGGTCTGGGGGCTGCCGCGGCTGGCAGCCCCGCATGTGGGCGCTCTTCGAGGATCCCTAC
TCCTCCCGGGCCGCTAGGGTAGTGGCCTTTGCCTCTCTCTTCTTCATCCTGGTCTCCATC
ACCACTTTCTGCCTGGAGACCCATGAGGCCTTTAATATCGACCGCAACGTGACAGAGATC
CTCCGCGTAGGGAACATCACCAGCGTGCACTTCCGGCGGGAGGTAGAGACAGAGCCCATC
CTGACCTACATCGAGGGCGTATGTGTGCTGTGGTTCACACTGGAGTTCCTGGTGCGCATC
GTGTGCTGCCCCGACACGCTGGACTTCGTCAAGAACCTGCTCAACATCATCGACTTTGTG
GCCATCCTGCCCTTCTACCTGGAGGTGGGGCTGAGCGGCCTGTCATCCAAGGCGGCCCGC
GACGTGCTGGGCTTCCTGCGCGTGGTGCGCTTCGTGCGCATCCTGCGTATCTTCAAGCTC
ACACGCCACTTCGTGGGGCTACGCGTGCTGGGCCACACCCTGAGGGCCAGCACCAATGAG
TTCCTGCTGCTTATCATCTTCCTGGCCCTGGGTGTGCTCATCTTTGCCACCATGATCTAC
TACGCTGAGCGCATTGGGGCCAGGCCCTCCGACCCTCGGGGTAATGACCACACCGACTTC
AAGAACATCCCCATTGGCTTCTGGTGGGCTGTGGTCACCATGACGACACTGGGCTACGGA
GACATGTACCCCAAGACGTGGTCAGGCATGCTGGTAGGGGCACTGTGTGCACTGGCTGGC
GTGCTCACCATCGCCATGCCGGTGCCTGTCATCGTCAACAACTTCGGCATGTACTACTCC
CTGGCCATGGCCAAGCAGAAGCTGCCCAAGAAACGGAAGAAGCACGTGCCACGGCCGGCG
CAGCTGGAGTCACCCATGTACTGCAAGTCTGAGGAGACTTCCCCCCGGGACAGCACCTGC
AGTGATACCAGCCCCCCTGCCCGGGAAGAGGGTATGATCGAGAGGAAACGGGCAGACTCT
AAGCAGAATGGCGATGCCAACGCAGTGCTGTCTGATGAGGAGGGAGCTGGCCTCACCCAA
CCCCTGGCCTCCTCCCCGACCCCCGAGGAGCGCCGGGCCCTGCGACGCTCCACCACTCGA
GACAGAAACAAGAAGGCAGCTGCCTGCTTCCTGCTCAGCACTGGGGACTATGCCTGCGCC
GATGGTAGTGTCCGGAAAGGCACATTCGTCCTCCGTGACCTTCCCCTTCAGCATTCACCT
GAGGCTGCATGCCCTCCAACTGCTGGGACTCTGTTCCTGCCACATTGA

Protein Properties

Number of Residues

635

Molecular Weight

69766.1

Theoretical pI

6.98

Pfam Domain Function

Ion_trans (PF00520 )
K_tetra (PF02214 )
Potassium_chann (PF11404 )

Signals

["None"]

Transmembrane Regions

["227-247", "278-298", "313-333", "345-364", "381-401", "452-472"]

Protein Sequence

>Potassium voltage-gated channel subfamily C member 4
MISSVCVSSYRGRKSGNKPPSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGT
RLAWLADPDGGGRPETDGGGVGSSGSSGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPAD
VCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDD
ERELALQRLGPHEGGAGHGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSI
TTFCLETHEAFNIDRNVTEILRVGNITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRI
VCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKL
TRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDF
KNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYS
LAMAKQKLPKKRKKHVPRPAQLESPMYCKSEETSPRDSTCSDTSPPAREEGMIERKRADS
KQNGDANAVLSDEEGAGLTQPLASSPTPEERRALRRSTTRDRNKKAAACFLLSTGDYACA
DGSVRKGTFVLRDLPLQHSPEAACPPTAGTLFLPH

External Links

GenBank ID Protein

56204186

UniProtKB/Swiss-Prot ID

Q03721

UniProtKB/Swiss-Prot Entry Name

KCNC4_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AL137790

GeneCard ID