| Identification |
|---|
| HMDB Protein ID
| CDBP04796 |
| Secondary Accession Numbers
| Not Available |
| Name
| CD320 antigen |
| Description
| Not Available |
| Synonyms
|
- 8D6 antigen
- CD320 antigen
- FDC-SM-8D6
- FDC-signaling molecule 8D6
- TCblR
- Transcobalamin receptor
|
| Gene Name
| CD320 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in growth factor activity |
| Specific Function
| Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC). CD320 augments the proliferation of PC precursors generated by IL-10. Receptor for the cellular uptake of transcobalamin bound cobalamin |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Membrane
- Single-pass type I membrane protein (Potential)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 19p13.3-p13.2 |
| SNPs
| CD320 |
| Gene Sequence
|
>849 bp
ATGAGCGGCGGTTGGATGGCGCAGGTTGGAGCGTGGCGAACAGGGGCTCTGGGCCTGGCG
CTGCTGCTGCTGCTCGGCCTCGGACTAGGCCTGGAGGCCGCCGCGAGCCCGCTTTCCACC
CCGACCTCTGCCCAGGCCGCAGGCCCCAGCTCAGGCTCGTGCCCACCCACCAAGTTCCAG
TGCCGCACCAGTGGCTTATGCGTGCCCCTCACCTGGCGCTGCGACAGGGACTTGGACTGC
AGCGATGGCAGCGATGAGGAGGAGTGCAGGATTGAGCCATGTACCCAGAAAGGGCAATGC
CCACCGCCCCCTGGCCTCCCCTGCCCCTGCACCGGCGTCAGTGACTGCTCTGGGGGAACT
GACAAGAAACTGCGCAACTGCAGCCGCCTGGCCTGCCTAGCAGGCGAGCTCCGTTGCACG
CTGAGCGATGACTGCATTCCACTCACGTGGCGCTGCGACGGCCACCCAGACTGTCCCGAC
TCCAGCGACGAGCTCGGCTGTGGAACCAATGAGATCCTCCCGGAAGGGGATGCCACAACC
ATGGGGCCCCCTGTGACCCTGGAGAGTGTCACCTCTCTCAGGAATGCCACAACCATGGGG
CCCCCTGTGACCCTGGAGAGTGTCCCCTCTGTCGGGAATGCCACATCCTCCTCTGCCGGA
GACCAGTCTGGAAGCCCAACTGCCTATGGGGTTATTGCAGCTGCTGCGGTGCTCAGTGCA
AGCCTGGTCACCGCCACCCTCCTCCTTTTGTCCTGGCTCCGAGCCCAGGAGCGCCTCCGC
CCACTGGGGTTACTGGTGGCCATGAAGGAGTCCCTGCTGCTGTCAGAACAGAAGACCTCG
CTGCCCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 282 |
| Molecular Weight
| 28990.6 |
| Theoretical pI
| 4.36 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>CD320 antigen
MSGGWMAQVGAWRTGALGLALLLLLGLGLGLEAAASPLSTPTSAQAAGPSSGSCPPTKFQ
CRTSGLCVPLTWRCDRDLDCSDGSDEEECRIEPCTQKGQCPPPPGLPCPCTGVSDCSGGT
DKKLRNCSRLACLAGELRCTLSDDCIPLTWRCDGHPDCPDSSDELGCGTNEILPEGDATT
MGPPVTLESVTSLRNATTMGPPVTLESVPSVGNATSSSAGDQSGSPTAYGVIAAAAVLSA
SLVTATLLLLSWLRAQERLRPLGLLVAMKESLLLSEQKTSLP
|
| External Links |
|---|
| GenBank ID Protein
| 7706111 |
| UniProtKB/Swiss-Prot ID
| Q9NPF0 |
| UniProtKB/Swiss-Prot Entry Name
| CD320_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_016579.3 |
| GeneCard ID
| CD320 |
| GenAtlas ID
| CD320 |
| HGNC ID
| HGNC:16692 |
| References |
|---|
| General References
| Not Available |