| Identification |
|---|
| HMDB Protein ID
| CDBP04782 |
| Secondary Accession Numbers
| Not Available |
| Name
| Oxoeicosanoid receptor 1 |
| Description
| Not Available |
| Synonyms
|
- 5-oxo-ETE G-protein coupled receptor
- G-protein coupled receptor 170
- G-protein coupled receptor R527
- G-protein coupled receptor TG1019
|
| Gene Name
| OXER1 |
| Protein Type
| Receptor |
| Biological Properties |
|---|
| General Function
| Involved in G-protein coupled receptor protein signaling pathway |
| Specific Function
| Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins |
| GO Classification
|
| Component |
| cell part |
| membrane part |
| intrinsic to membrane |
| integral to membrane |
| Process |
| signaling |
| signaling pathway |
| cell surface receptor linked signaling pathway |
| g-protein coupled receptor protein signaling pathway |
|
| Cellular Location
|
- Cell membrane
- Multi-pass membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:2 |
| Locus
| 2p21 |
| SNPs
| OXER1 |
| Gene Sequence
|
>1272 bp
ATGTTGTGTCACCGTGGTGGCCAGCTGATAGTGCCAATCATCCCACTTTGCCCTGAGCAC
TCCTGCAGGGGTAGAAGACTCCAGAACCTTCTCTCAGGCCCATGGCCCAAGCAGCCCATG
GAACTTCATAACCTGAGCTCTCCATCTCCCTCTCTCTCCTCCTCTGTTCTCCCTCCCTCC
TTCTCTCCCTCACCCTCCTCTGCTCCCTCTGCCTTTACCACTGTGGGGGGGTCCTCTGGA
GGGCCCTGCCACCCCACCTCTTCCTCGCTGGTGTCTGCCTTCCTGGCACCAATCCTGGCC
CTGGAGTTTGTCCTGGGCCTGGTGGGGAACAGTTTGGCCCTCTTCATCTTCTGCATCCAC
ACGCGGCCCTGGACCTCCAACACGGTGTTCCTGGTCAGCCTGGTGGCCGCTGACTTCCTC
CTGATCAGCAACCTGCCCCTCCGCGTGGACTACTACCTCCTCCATGAGACCTGGCGCTTT
GGGGCTGCTGCCTGCAAAGTCAACCTCTTCATGCTGTCCACCAACCGCACGGCCAGCGTT
GTCTTCCTCACAGCCATCGCACTCAACCGCTACCTGAAGGTGGTGCAGCCCCACCACGTG
CTGAGCCGTGCTTCCGTGGGGGCAGCTGCCCGGGTGGCCGGGGGACTCTGGGTGGGCATC
CTGCTCCTCAACGGGCACCTGCTCCTGAGCACCTTCTCCGGCCCCTCCTGCCTCAGCTAC
AGGGTGGGCACGAAGCCCTCGGCCTCGCTCCGCTGGCACCAGGCACTGTACCTGCTGGAG
TTCTTCCTGCCACTGGCGCTCATCCTCTTTGCTATTGTGAGCATTGGGCTCACCATCCGG
AACCGTGGTCTGGGCGGGCAGGCAGGCCCGCAGAGGGCCATGCGTGTGCTGGCCATGGTG
GTGGCCGTCTACACCATCTGCTTCTTGCCCAGCATCATCTTTGGCATGGCTTCCATGGTG
GCTTTCTGGCTGTCCGCCTGCCGATCCCTGGACCTCTGCACACAGCTCTTCCATGGCTCC
CTGGCCTTCACCTACCTCAACAGTGTCCTGGACCCCGTGCTCTACTGCTTCTCTAGCCCC
AACTTCCTCCACCAGAGCCGGGCCTTGCTGGGCCTCACGCGGGGCCGGCAGGGCCCAGTG
AGCGACGAGAGCTCCTACCAACCCTCCAGGCAGTGGCGCTACCGGGAGGCCTCTAGGAAG
GCGGAGGCCATAGGGAAGCTGAAAGTGCAGGGCGAGGTCTCTCTGGAAAAGGAAGGCTCC
TCCCAGGGCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 423 |
| Molecular Weight
| 45810.0 |
| Theoretical pI
| 9.97 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
- ["98-118", "127-147", "169-191", "212-232", "255-275", "296-316", "337-357"]
|
| Protein Sequence
|
>Oxoeicosanoid receptor 1
MLCHRGGQLIVPIIPLCPEHSCRGRRLQNLLSGPWPKQPMELHNLSSPSPSLSSSVLPPS
FSPSPSSAPSAFTTVGGSSGGPCHPTSSSLVSAFLAPILALEFVLGLVGNSLALFIFCIH
TRPWTSNTVFLVSLVAADFLLISNLPLRVDYYLLHETWRFGAAACKVNLFMLSTNRTASV
VFLTAIALNRYLKVVQPHHVLSRASVGAAARVAGGLWVGILLLNGHLLLSTFSGPSCLSY
RVGTKPSASLRWHQALYLLEFFLPLALILFAIVSIGLTIRNRGLGGQAGPQRAMRVLAMV
VAVYTICFLPSIIFGMASMVAFWLSACRSLDLCTQLFHGSLAFTYLNSVLDPVLYCFSSP
NFLHQSRALLGLTRGRQGPVSDESSYQPSRQWRYREASRKAEAIGKLKVQGEVSLEKEGS
SQG
|
| External Links |
|---|
| GenBank ID Protein
| 22507376 |
| UniProtKB/Swiss-Prot ID
| Q8TDS5 |
| UniProtKB/Swiss-Prot Entry Name
| OXER1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_148962.4 |
| GeneCard ID
| OXER1 |
| GenAtlas ID
| OXER1 |
| HGNC ID
| HGNC:24884 |
| References |
|---|
| General References
| Not Available |