| Identification |
|---|
| HMDB Protein ID
| CDBP04760 |
| Secondary Accession Numbers
| Not Available |
| Name
| WD repeat domain phosphoinositide-interacting protein 1 |
| Description
| Not Available |
| Synonyms
|
- Atg18 protein homolog
- WD40 repeat protein interacting with phosphoinositides of 49 kDa
- WIPI 49 kDa
- WIPI-1
|
| Gene Name
| WIPI1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in androgen receptor binding |
| Specific Function
| May play a role in autophagy. May regulate the trafficking of proteins involved in the mannose-6-phosphate receptor (MPR) recycling pathway |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Cytoplasmic vesicle
- Golgi apparatus
- Endosome
- trans-Golgi network
- clathrin-coated vesicle
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 17q24.2 |
| SNPs
| WIPI1 |
| Gene Sequence
|
>1341 bp
ATGGAGGCCGAGGCCGCGGACGCTCCCCCGGGCGGGGTTGAGTCGGCGCTCAGCTGCTTC
TCTTTCAACCAGGACTGCACATCCCTAGCAACTGGAACTAAAGCCGGGTATAAGCTGTTT
TCTCTGAGTTCTGTGGAGCAGCTGGATCAAGTCCACGGAAGCAATGAAATCCCGGACGTC
TACATCGTGGAGCGCCTCTTCTCCAGCAGCCTGGTGGTGGTAGTCAGTCACACAAAACCA
CGGCAGATGAACGTGTATCACTTCAAGAAAGGCACAGAGATCTGTAATTACAGCTACTCC
AGCAACATCTTGTCCATAAGGCTGAACCGGCAAAGGCTGCTGGTTTGCCTAGAAGAGTCC
ATTTATATTCACAACATTAAAGACATGAAGCTGTTGAAGACCCTCCTGGATATTCCTGCA
AACCCAACAGGTCTATGTGCTCTCTCTATCAACCATTCCAATTCTTACCTGGCCTATCCT
GGAAGCCTGACTTCAGGGGAGATTGTGCTTTATGATGGAAACTCCCTGAAAACAGTCTGC
ACTATTGCTGCCCATGAGGGAACACTAGCTGCCATCACCTTCAATGCCTCAGGCTCCAAA
CTAGCAAGTGCGTCTGAAAAAGGCACAGTCATCCGGGTGTTCTCTGTCCCTGATGGGCAA
AAGCTCTATGAGTTCCGGAGAGGGATGAAAAGGTATGTGACAATCAGCTCTCTAGTGTTC
AGTATGGATTCACAATTCCTCTGCGCCTCCAGTAACACCGAGACGGTACACATCTTCAAG
CTGGAACAGGTCACCAACAGTCGACCAGAAGAGCCTTCGACCTGGAGTGGCTACATGGGA
AAGATGTTTATGGCTGCTACCAACTACCTCCCTACCCAGGTGTCAGACATGATGCATCAG
GACAGGGCTTTTGCCACTGCACGCTTGAACTTCTCCGGACAGAGGAACATCTGTACCCTC
TCAACGATCCAGAAGTTGCCACGGCTGCTAGTTGCGTCATCCAGTGGACACCTTTATATG
TACAATTTGGATCCTCAGGATGGAGGAGAGTGTGTCTTAATCAAAACCCACAGCTTGCTT
GGCTCAGGAACAACAGAAGAGAATAAAGAAAATGACCTCAGACCTTCCTTACCTCAGTCT
TATGCAGCGACCGTAGCCAGACCAAGTGCATCTTCAGCCTCCACGGTGCCAGGTTATTCT
GAGGACGGCGGGGCGCTGCGAGGAGAAGTTATTCCTGAACATGAGTTTGCGACGGGACCA
GTGTGTCTTGATGATGAGAATGAGTTTCCTCCTATAATCTTGTGCCGTGGAAATCAGAAG
GGCAAAACGAAGCAGTCATGA
|
| Protein Properties |
|---|
| Number of Residues
| 446 |
| Molecular Weight
| 48672.6 |
| Theoretical pI
| 6.58 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>WD repeat domain phosphoinositide-interacting protein 1
MEAEAADAPPGGVESALSCFSFNQDCTSLATGTKAGYKLFSLSSVEQLDQVHGSNEIPDV
YIVERLFSSSLVVVVSHTKPRQMNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCLEES
IYIHNIKDMKLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLKTVC
TIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISSLVF
SMDSQFLCASSNTETVHIFKLEQVTNSRPEEPSTWSGYMGKMFMAATNYLPTQVSDMMHQ
DRAFATARLNFSGQRNICTLSTIQKLPRLLVASSSGHLYMYNLDPQDGGECVLIKTHSLL
GSGTTEENKENDLRPSLPQSYAATVARPSASSASTVPGYSEDGGALRGEVIPEHEFATGP
VCLDDENEFPPIILCRGNQKGKTKQS
|
| External Links |
|---|
| GenBank ID Protein
| 157388939 |
| UniProtKB/Swiss-Prot ID
| Q5MNZ9 |
| UniProtKB/Swiss-Prot Entry Name
| WIPI1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_017983.5 |
| GeneCard ID
| WIPI1 |
| GenAtlas ID
| WIPI1 |
| HGNC ID
| HGNC:25471 |
| References |
|---|
| General References
| Not Available |