Showing Protein DNA-binding protein inhibitor ID-3 (CDBP04750)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 0 compounds
Identification
HMDB Protein ID CDBP04750
Secondary Accession Numbers Not Available
Name DNA-binding protein inhibitor ID-3
Description Not Available
Synonyms
  1. Class B basic helix-loop-helix protein 25
  2. Helix-loop-helix protein HEIR-1
  3. ID-like protein inhibitor HLH 1R21
  4. Inhibitor of DNA binding 3
  5. bHLHb25
Gene Name ID3
Protein Type Transcription Factor
Biological Properties
General Function Involved in transcription regulator activity
Specific Function ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. ID-3 inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. May inhibit other transcription factors
GO Classification
Component
organelle
membrane-bounded organelle
intracellular membrane-bounded organelle
nucleus
Function
transcription regulator activity
Process
biological regulation
regulation of biological process
regulation of metabolic process
regulation of macromolecule metabolic process
regulation of gene expression
regulation of transcription
Cellular Location
  1. Nucleus
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 1p36.13-p36.12
SNPs ID3
Gene Sequence 
>360 bp
ATGAAGGCGCTGAGCCCGGTGCGCGGCTGCTACGAGGCGGTGTGCTGCCTGTCGGAACGC
AGTCTGGCCATCGCCCGGGGCCGAGGGAAGGGCCCGGCAGCTGAGGAGCCGCTGAGCTTG
CTGGACGACATGAACCACTGCTACTCCCGCCTGCGGGAACTGGTACCCGGAGTCCCGAGA
GGCACTCAGCTTAGCCAGGTGGAAATCCTACAGCGCGTCATCGACTACATTCTCGACCTG
CAGGTAGTCCTGGCCGAGCCAGCCCCTGGACCCCCTGATGGCCCCCACCTTCCCATCCAG
ACAGCCGAGCTCGCTCCGGAACTTGTCATCTCCAACGACAAAAGGAGCTTTTGCCACTGA
Protein Properties
Number of Residues 119
Molecular Weight 12968.8
Theoretical pI 5.64
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>DNA-binding protein inhibitor ID-3
MKALSPVRGCYEAVCCLSERSLAIARGRGKGPAAEEPLSLLDDMNHCYSRLRELVPGVPR
GTQLSQVEILQRVIDYILDLQVVLAEPAPGPPDGPHLPIQTAELAPELVISNDKRSFCH
GenBank ID Protein 158261029
UniProtKB/Swiss-Prot ID Q02535
UniProtKB/Swiss-Prot Entry Name ID3_HUMAN
PDB IDs Not Available
GenBank Gene ID AK290003
GeneCard ID ID3
GenAtlas ID ID3
HGNC ID HGNC:5362
References
General References Not Available