| Identification |
|---|
| HMDB Protein ID
| CDBP04740 |
| Secondary Accession Numbers
| Not Available |
| Name
| Fibroblast growth factor 5 |
| Description
| Not Available |
| Synonyms
|
- FGF-5
- HBGF-5
- Heparin-binding growth factor 5
- Smag-82
|
| Gene Name
| FGF5 |
| Protein Type
| Receptor |
| Biological Properties |
|---|
| General Function
| Involved in growth factor activity |
| Specific Function
| Functions as an inhibitor of hair elongation by promoting progression from anagen, the growth phase of the hair follicle, into catagen the apoptosis-induced regression phase |
| GO Classification
|
| Function |
| protein binding |
| receptor binding |
| growth factor activity |
| binding |
|
| Cellular Location
|
- Secreted (Potential)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:4 |
| Locus
| 4q21 |
| SNPs
| FGF5 |
| Gene Sequence
|
>807 bp
ATGAGCTTGTCCTTCCTCCTCCTCCTCTTCTTCAGCCACCTGATCCTCAGCGCCTGGGCT
CACGGGGAGAAGCGTCTCGCCCCCAAAGGGCAACCCGGACCCGCTGCCACTGATAGGAAC
CCTAGAGGCTCCAGCAGCAGACAGAGCAGCAGTAGCGCTATGTCTTCCTCTTCTGCCTCC
TCCTCCCCCGCAGCTTCTCTGGGCAGCCAAGGAAGTGGCTTGGAGCAGAGCAGTTTCCAG
TGGAGCCCCTCGGGGCGCCGGACCGGCAGCCTCTACTGCAGAGTGGGCATCGGTTTCCAT
CTGCAGATCTACCCGGATGGCAAAGTCAATGGATCCCACGAAGCCAATATGTTAAGTGTT
TTGGAAATATTTGCTGTGTCTCAGGGGATTGTAGGAATACGAGGAGTTTTCAGCAACAAA
TTTTTAGCGATGTCAAAAAAAGGAAAACTCCATGCAAGTGCCAAGTTCACAGATGACTGC
AAGTTCAGGGAGCGTTTTCAAGAAAATAGCTATAATACCTATGCCTCAGCAATACATAGA
ACTGAAAAAACAGGGCGGGAGTGGTATGTGGCCCTGAATAAAAGAGGAAAAGCCAAACGA
GGGTGCAGCCCCCGGGTTAAACCCCAGCATATCTCTACCCATTTTCTGCCAAGATTCAAG
CAGTCGGAGCAGCCAGAACTTTCTTTCACGGTTACTGTTCCTGAAAAGAAAAAGCCACCT
AGCCCTATCAAGCCAAAGATTCCCCTTTCTGCACCTCGGAAAAATACCAACTCAGTGAAA
TACAGACTCAAGTTTCGCTTTGGATAA
|
| Protein Properties |
|---|
| Number of Residues
| 268 |
| Molecular Weight
| 29550.5 |
| Theoretical pI
| 11.21 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Fibroblast growth factor 5
MSLSFLLLLFFSHLILSAWAHGEKRLAPKGQPGPAATDRNPRGSSSRQSSSSAMSSSSAS
SSPAASLGSQGSGLEQSSFQWSPSGRRTGSLYCRVGIGFHLQIYPDGKVNGSHEANMLSV
LEIFAVSQGIVGIRGVFSNKFLAMSKKGKLHASAKFTDDCKFRERFQENSYNTYASAIHR
TEKTGREWYVALNKRGKAKRGCSPRVKPQHISTHFLPRFKQSEQPELSFTVTVPEKKKPP
SPIKPKIPLSAPRKNTNSVKYRLKFRFG
|
| External Links |
|---|
| GenBank ID Protein
| 73486655 |
| UniProtKB/Swiss-Prot ID
| P12034 |
| UniProtKB/Swiss-Prot Entry Name
| FGF5_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_004464.3 |
| GeneCard ID
| FGF5 |
| GenAtlas ID
| FGF5 |
| HGNC ID
| HGNC:3683 |
| References |
|---|
| General References
| Not Available |