| Identification |
|---|
| HMDB Protein ID
| CDBP04721 |
| Secondary Accession Numbers
| Not Available |
| Name
| Ornithine decarboxylase antizyme 3 |
| Description
| Not Available |
| Synonyms
|
- AZ3
- ODC-Az 3
|
| Gene Name
| OAZ3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in enzyme inhibitor activity |
| Specific Function
| Binds to, and destabilizes, ornithine decarboxylase. Does not accelerate ornithine decarboxylase degeneration. OAZ3 probably plays a key role in spermatogenesis by regulating the intracellular concentration of polyamines in haploid germ cells |
| GO Classification
|
| Function |
| enzyme regulator activity |
| enzyme inhibitor activity |
| ornithine decarboxylase inhibitor activity |
|
| Cellular Location
|
- Nucleus
- Cytoplasm
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 1q21.3 |
| SNPs
| OAZ3 |
| Gene Sequence
|
>564 bp
ATGCTGCCTCGTTGTTATAAAAGCATCACTTATAAGGAAGAGGAGGACTTGACACTCCAG
CCCCGTTCCTGCCTCCAGTGCTCTGAGTCCCTAGTAGGCCTCCAGGAGGGCAAAAGCACC
GAGCAGGGTAACCACGACCAGCTTAAAGAACTGTATTCGGCTGGGAACTTGACGGTGCTG
GCTACTGACCCCCTGCTCCACCAGGACCCAGTACAGTTAGACTTTCACTTCCGCCTTACC
TCCCAGACCTCTGCCCATTGGCACGGCCTTCTCTGTGACCGTCGACTCTTCCTGGATATC
CCATATCAGGCCTTGGATCAAGGCAACCGGGAAAGTTTGACTGCAACCCTGGAGTACGTG
GAAGAGAAGACAAATGTGGACTCTGTGTTTGTGAACTTCCAGAATGATCGGAACGACAGA
GGTGCCCTGCTGCGGGCCTTCAGCTACATGGGCTTTGAGGTGGTCAGACCAGATCACCCT
GCCCTCCCTCCCTTGGACAATGTCATCTTTATGGTGTATCCCCTTGAAAGGGATGTTGGC
CACCTGCCCAGTGAGCCTCCTTGA
|
| Protein Properties |
|---|
| Number of Residues
| 187 |
| Molecular Weight
| 21374.8 |
| Theoretical pI
| 4.67 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Ornithine decarboxylase antizyme 3
MLPRCYKSITYKEEEDLTLQPRSCLQCSESLVGLQEGKSTEQGNHDQLKELYSAGNLTVL
ATDPLLHQDPVQLDFHFRLTSQTSAHWHGLLCDRRLFLDIPYQALDQGNRESLTATLEYV
EEKTNVDSVFVNFQNDRNDRGALLRAFSYMGFEVVRPDHPALPPLDNVIFMVYPLERDVG
HLPSEPP
|
| External Links |
|---|
| GenBank ID Protein
| 5802609 |
| UniProtKB/Swiss-Prot ID
| Q9UMX2 |
| UniProtKB/Swiss-Prot Entry Name
| OAZ3_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF175296 |
| GeneCard ID
| OAZ3 |
| GenAtlas ID
| OAZ3 |
| HGNC ID
| HGNC:8097 |
| References |
|---|
| General References
| Not Available |