Showing Protein Peptidyl-prolyl cis-trans isomerase H (CDBP04710)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP04710
Secondary Accession Numbers Not Available
Name Peptidyl-prolyl cis-trans isomerase H
Description Not Available
Synonyms
  1. CypH
  2. PPIase H
  3. Rotamase H
  4. Small nuclear ribonucleoprotein particle-specific cyclophilin H
  5. U-snRNP-associated cyclophilin SnuCyp-20
  6. USA-CYP
Gene Name PPIH
Protein Type Enzyme
Biological Properties
General Function Involved in peptidyl-prolyl cis-trans isomerase activity
Specific Function PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Participates in pre-mRNA splicing. May play a role in the assembly of the U4/U5/U6 tri-snRNP complex. May act as a chaperone
GO Classification
Function
catalytic activity
cis-trans isomerase activity
peptidyl-prolyl cis-trans isomerase activity
isomerase activity
Process
metabolic process
macromolecule metabolic process
cellular protein metabolic process
protein folding
protein metabolic process
Cellular Location
  1. Cytoplasm
  2. Nucleus speckle
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 1p34.1
SNPs PPIH
Gene Sequence 
>534 bp
ATGGCGGTGGCAAATTCAAGTCCTGTTAACCCCGTGGTGTTCTTTGATGTCAGTATTGGC
GGTCAGGAAGTTGGCCGCATGAAGATCGAGCTCTTTGCAGACGTTGTGCCTAAGACGGCC
GAGAACTTTAGGCAGTTCTGCACCGGAGAATTCAGGAAAGATGGGGTTCCAATAGGATAC
AAAGGAAGCACCTTCCACAGGGTCATAAAGGATTTCATGATTCAGGGTGGAGATTTTGTT
AATGGAGATGGTACTGGAGTCGCCAGTATTTACCGGGGGCCATTTGCAGATGAAAATTTT
AAACTTAGACACTCAGCTCCAGGCCTGCTTTCCATGGCGAACAGTGGTCCAAGTACAAAT
GGCTGTCAGTTCTTTATCACCTGCTCTAAGTGCGATTGGCTGGATGGGAAGCATGTGGTG
TTTGGAAAAATCATCGATGGACTTCTAGTGATGAGAAAGATTGAGAATGTTCCCACAGGC
CCCAACAATAAGCCCAAGCTACCTGTGGTGATCTCGCAGTGTGGGGAGATGTAG
Protein Properties
Number of Residues 177
Molecular Weight 19208.0
Theoretical pI 8.22
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Peptidyl-prolyl cis-trans isomerase H
MAVANSSPVNPVVFFDVSIGGQEVGRMKIELFADVVPKTAENFRQFCTGEFRKDGVPIGY
KGSTFHRVIKDFMIQGGDFVNGDGTGVASIYRGPFADENFKLRHSAPGLLSMANSGPSTN
GCQFFITCSKCDWLDGKHVVFGKIIDGLLVMRKIENVPTGPNNKPKLPVVISQCGEM
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID O43447
UniProtKB/Swiss-Prot Entry Name PPIH_HUMAN
PDB IDs
GenBank Gene ID AF016371
GeneCard ID PPIH
GenAtlas ID PPIH
HGNC ID HGNC:14651
References
General References Not Available