Cannabis Compound Database: Showing Protein Peptidyl-prolyl cis-trans isomerase B (CDBP04707)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP04707

Secondary Accession Numbers

Not Available

Name

Peptidyl-prolyl cis-trans isomerase B

Description

Not Available

Synonyms

CYP-S1
Cyclophilin B
PPIase B
Rotamase B
S-cyclophilin
SCYLP

Gene Name

PPIB

Protein Type

Enzyme

Biological Properties

General Function

Involved in peptidyl-prolyl cis-trans isomerase activity

Specific Function

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides

GO Classification

Function
catalytic activity
cis-trans isomerase activity
peptidyl-prolyl cis-trans isomerase activity
isomerase activity
Process
macromolecule metabolic process
cellular protein metabolic process
protein folding
protein metabolic process
metabolic process

Cellular Location

Melanosome
Endoplasmic reticulum lumen

Pathways

Name	SMPDB/Pathwhiz	KEGG
Retinol Metabolism
Vitamin A Deficiency		Not Available
Sorafenib Metabolism Pathway		Not Available
Irinotecan Action Pathway		Not Available
Irinotecan Metabolism Pathway		Not Available

Gene Properties

Chromosome Location

Chromosome:1

Locus

15q21-q22

SNPs

PPIB

Gene Sequence

>651 bp
ATGCTGCGCCTCTCCGAACGCAACATGAAGGTGCTCCTTGCCGCCGCCCTCATCGCGGGG
TCCGTCTTCTTCCTGCTGCTGCCGGGACCTTCTGCGGCCGATGAGAAGAAGAAGGGGCCC
AAAGTCACCGTCAAGGTGTATTTTGACCTACGAATTGGAGATGAAGATGTAGGCCGGGTG
ATCTTTGGTCTCTTCGGAAAGACTGTTCCAAAAACAGTGGATAATTTTGTGGCCTTAGCT
ACAGGAGAGAAAGGATTTGGCTACAAAAACAGCAAATTCCATCGTGTAATCAAGGACTTC
ATGATCCAGGGCGGAGACTTCACCAGGGGAGATGGCACAGGAGGAAAGAGCATCTACGGT
GAGCGCTTCCCCGATGAGAACTTCAAACTGAAGCACTACGGGCCTGGCTGGGTGAGCATG
GCCAACGCAGGCAAAGACACCAACGGCTCCCAGTTCTTCATCACGACAGTCAAGACAGCC
TGGCTAGATGGCAAGCATGTGGTGTTTGGCAAAGTTCTAGAGGGCATGGAGGTGGTGCGG
AAGGTGGAGAGCACCAAGACAGACAGCCGGGATAAACCCCTGAAGGATGTGATCATCGCA
GACTGCGGCAAGATCGAGGTGGAGAAGCCCTTTGCCATCGCCAAGGAGTAG

Protein Properties

Number of Residues

216

Molecular Weight

23742.4

Theoretical pI

10.07

Pfam Domain Function

Pro_isomerase (PF00160 )

Signals

["1-33"]

Transmembrane Regions

["None"]

Protein Sequence

>Peptidyl-prolyl cis-trans isomerase B
MLRLSERNMKVLLAAALIAGSVFFLLLPGPSAADEKKKGPKVTVKVYFDLRIGDEDVGRV
IFGLFGKTVPKTVDNFVALATGEKGFGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYG
ERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTVKTAWLDGKHVVFGKVLEGMEVVR
KVESTKTDSRDKPLKDVIIADCGKIEVEKPFAIAKE

External Links

GenBank ID Protein

Not Available

UniProtKB/Swiss-Prot ID

P23284

UniProtKB/Swiss-Prot Entry Name

PPIB_HUMAN

PDB IDs