| Identification |
|---|
| HMDB Protein ID
| CDBP04693 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protein phosphatase 1 regulatory subunit 3C |
| Description
| Not Available |
| Synonyms
|
- PP1 subunit R5
- PTG
- Protein phosphatase 1 regulatory subunit 5
- Protein targeting to glycogen
|
| Gene Name
| PPP1R3C |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein serine/threonine phosphatase activity |
| Specific Function
| Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in a variety of cell types |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 10q23-q24 |
| SNPs
| PPP1R3C |
| Gene Sequence
|
>954 bp
ATGAGCTGCACCAGAATGATCCAGGTTTTAGATCCACGTCCTTTGACAAGTTCGGTCATG
CCCGTGGATGTGGCCATGAGGCTTTGCTTGGCACATTCACCACCTGTGAAGAGTTTCCTG
GGCCCGTACGATGAATTTCAACGACGACATTTTGTGAATAAATTAAAGCCCCTGAAATCA
TGTCTCAATATAAAACACAAAGCCAAATCACAGAATGACTGGAAGTGCTCACACAACCAA
GCCAAGAAGCGCGTTGTGTTTGCTGACTCCAAGGGCCTCTCTCTCACTGCGATCCATGTC
TTCTCCGACCTCCCAGAAGAACCAGCGTGGGATCTGCAGTTTGATCTCTTGGACCTTAAT
GATATCTCCTCTGCCTTAAAACACCACGAGGAGAAAAACTTGATTTTAGATTTCCCTCAG
CCTTCAACCGATTACTTAAGTTTCCGGAGCCACTTTCAGAAGAACTTTGTCTGTCTGGAG
AACTGCTCGTTGCAAGAGCGAACAGTGACAGGGACTGTTAAAGTCAAAAATGTGAGTTTT
GAGAAGAAAGTTCAGATCCGTATCACTTTCGATTCTTGGAAAAACTACACTGACGTAGAC
TGTGTCTATATGAAAAATGTGTATGGTGGCACAGATAGTGATACCTTCTCATTTGCCATT
GACTTACCCCCTGTCATTCCAACTGAGCAGAAAATTGAGTTCTGCATTTCTTACCATGCT
AATGGGCAAGTCTTTTGGGACAACAATGATGGTCAGAATTATAGAATTGTTCATGTTCAA
TGGAAGCCTGATGGGGTGCAGACACAGATGGCACCCCAGGACTGTGCATTCCACCAGACG
TCTCCTAAGACAGAGTTAGAGTCAACAATCTTTGGCAGTCCGAGGCTGGCTAGTGGGCTC
TTCCCAGAGTGGCAGAGCTGGGGGAGAATGGAGAACTTGGCCTCTTATCGATGA
|
| Protein Properties |
|---|
| Number of Residues
| 317 |
| Molecular Weight
| 36445.2 |
| Theoretical pI
| 7.52 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protein phosphatase 1 regulatory subunit 3C
MSCTRMIQVLDPRPLTSSVMPVDVAMRLCLAHSPPVKSFLGPYDEFQRRHFVNKLKPLKS
CLNIKHKAKSQNDWKCSHNQAKKRVVFADSKGLSLTAIHVFSDLPEEPAWDLQFDLLDLN
DISSALKHHEEKNLILDFPQPSTDYLSFRSHFQKNFVCLENCSLQERTVTGTVKVKNVSF
EKKVQIRITFDSWKNYTDVDCVYMKNVYGGTDSDTFSFAIDLPPVIPTEQKIEFCISYHA
NGQVFWDNNDGQNYRIVHVQWKPDGVQTQMAPQDCAFHQTSPKTELESTIFGSPRLASGL
FPEWQSWGRMENLASYR
|
| External Links |
|---|
| GenBank ID Protein
| 189053715 |
| UniProtKB/Swiss-Prot ID
| Q9UQK1 |
| UniProtKB/Swiss-Prot Entry Name
| PPR3C_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AK313149 |
| GeneCard ID
| PPP1R3C |
| GenAtlas ID
| PPP1R3C |
| HGNC ID
| HGNC:9293 |
| References |
|---|
| General References
| Not Available |