Showing Protein Peptidyl-prolyl cis-trans isomerase FKBP5 (CDBP04688)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 0 compounds
Identification
HMDB Protein ID CDBP04688
Secondary Accession Numbers Not Available
Name Peptidyl-prolyl cis-trans isomerase FKBP5
Description Not Available
Synonyms
  1. 51 kDa FK506-binding protein
  2. 51 kDa FKBP
  3. 54 kDa progesterone receptor-associated immunophilin
  4. Androgen-regulated protein 6
  5. FF1 antigen
  6. FK506-binding protein 5
  7. FKBP-5
  8. FKBP-51
  9. FKBP54
  10. HSP90-binding immunophilin
  11. PPIase FKBP5
  12. Rotamase
  13. p54
Gene Name FKBP5
Protein Type Enzyme
Biological Properties
General Function Involved in protein folding
Specific Function Interacts with functionally mature heterooligomeric progesterone receptor complexes along with HSP90 and TEBP
GO Classification
Function
binding
Process
metabolic process
macromolecule metabolic process
cellular protein metabolic process
protein folding
protein metabolic process
Cellular Location
  1. Nucleus
  2. Cytoplasm
Pathways
Gene Properties
Chromosome Location Chromosome:6
Locus 6p21.31
SNPs FKBP5
Gene Sequence 
>1374 bp
ATGACTACTGATGAAGGTGCCAAGAACAATGAAGAAAGCCCCACAGCCACTGTTGCTGAG
CAGGGAGAGGATATTACCTCCAAAAAAGACAGGGGAGTATTAAAGATTGTCAAAAGAGTG
GGGAATGGTGAGGAAACGCCGATGATTGGAGACAAAGTTTATGTCCATTACAAAGGAAAA
TTGTCAAATGGAAAGAAGTTTGATTCCAGTCATGATAGAAATGAACCATTTGTCTTTAGT
CTTGGCAAAGGCCAAGTCATCAAGGCATGGGACATTGGGGTGGCTACCATGAAGAAAGGA
GAGATATGCCATTTACTGTGCAAACCAGAATATGCATATGGCTCGGCTGGCAGTCTCCCT
AAAATTCCCTCGAATGCAACTCTCTTTTTTGAGATTGAGCTCCTTGATTTCAAAGGAGAG
GATTTATTTGAAGATGGAGGCATTATCCGGAGAACCAAACGGAAAGGAGAGGGATATTCA
AATCCAAACGAAGGAGCAACAGTAGAAATCCACCTGGAAGGCCGCTGTGGTGGAAGGATG
TTTGACTGCAGAGATGTGGCATTCACTGTGGGCGAAGGAGAAGACCACGACATTCCAATT
GGAATTGACAAAGCTCTGGAGAAAATGCAGCGGGAAGAACAATGTATTTTATATCTTGGA
CCAAGATATGGTTTTGGAGAGGCAGGGAAGCCTAAATTTGGCATTGAACCTAATGCTGAG
CTTATATATGAAGTTACACTTAAGAGCTTCGAAAAGGCCAAAGAATCCTGGGAGATGGAT
ACCAAAGAAAAATTGGAGCAGGCTGCCATTGTCAAAGAGAAGGGAACCGTATACTTCAAG
GGAGGCAAATACATGCAGGCGGTGATTCAGTATGGGAAGATAGTGTCCTGGTTAGAGATG
GAATATGGTTTATCAGAAAAGGAATCGAAAGCTTCTGAATCATTTCTCCTTGCTGCCTTT
CTGAACCTGGCCATGTGCTACCTGAAGCTTAGAGAATACACCAAAGCTGTTGAATGCTGT
GACAAGGCCCTTGGACTGGACAGTGCCAATGAGAAAGGCTTGTATAGGAGGGGTGAAGCC
CAGCTGCTCATGAACGAGTTTGAGTCAGCCAAGGGTGACTTTGAGAAAGTGCTGGAAGTA
AACCCCCAGAATAAGGCTGCAAGACTGCAGATCTCCATGTGCCAGAAAAAGGCCAAGGAG
CACAACGAGCGGGACCGCAGGATATACGCCAACATGTTCAAGAAGTTTGCAGAGCAGGAT
GCCAAGGAAGAGGCCAATAAAGCAATGGGCAAGAAGACTTCAGAAGGGGTCACTAATGAA
AAAGGAACAGACAGTCAAGCAATGGAAGAAGAGAAACCTGAGGGCCACGTATGA
Protein Properties
Number of Residues 457
Molecular Weight 51211.8
Theoretical pI 5.66
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Peptidyl-prolyl cis-trans isomerase FKBP5
MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK
LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP
KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM
FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE
LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM
EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA
QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD
AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV
GenBank ID Protein 17998669
UniProtKB/Swiss-Prot ID Q13451
UniProtKB/Swiss-Prot Entry Name FKBP5_HUMAN
PDB IDs
GenBank Gene ID AF194172
GeneCard ID FKBP5
GenAtlas ID FKBP5
HGNC ID HGNC:3721
References
General References Not Available