Cannabis Compound Database: Showing Protein Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (CDBP04668)

Identification Biological properties Gene properties Protein properties External links References XML Show 3 compounds

Identification

HMDB Protein ID

CDBP04668

Secondary Accession Numbers

Not Available

Name

Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16

Description

Not Available

Synonyms

ATP-dependent RNA helicase #3
DEAH-box protein 16

Gene Name

DHX16

Protein Type

Enzyme

Biological Properties

General Function

Involved in nucleic acid binding

Specific Function

Probable ATP-binding RNA helicase involved in pre-mRNA splicing.

GO Classification

Biological Process
mRNA processing
RNA splicing
Cellular Component
nucleus
Function
atp binding
atp-dependent helicase activity
atpase activity
atpase activity, coupled
nucleic acid binding
nucleoside-triphosphatase activity
helicase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
pyrophosphatase activity
binding
catalytic activity
hydrolase activity
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
adenyl ribonucleotide binding
Molecular Function
nucleic acid binding
RNA helicase activity
ATP binding
ATP-dependent helicase activity

Cellular Location

Nucleus

Pathways

Name	SMPDB/Pathwhiz	KEGG
Spliceosome	Not Available

Gene Properties

Chromosome Location

Locus

6p21.3

SNPs

DHX16

Gene Sequence

>3126 bp
ATGGCGACGCCGGCGGGTCTGGAGCGCTGGGTTCAGGACGAGCTGCACTCGGTGTTGGGG
CTGAGCGAGCGGCACGTCGCCCAGTTTCTGATCGGTACCGCACAGCGCTGCACCTCTGCC
GAGGAGTTCGTGCAGCGCCTACGAGACACTGATACCTTGGATCTCAGTGGGCCGGCCCGG
GACTTCGCCCTGAGACTCTGGAACAAGGTACCACGAAAGGCAGTGGTAGAAAAGCCAGCT
CGGGCAGCAGAGCGAGAGGCCCGGGCCCTGCTGGAGAAGAACCGATCTTATAGGTTACTG
GAAGACAGTGAAGAGAGCAGTGAGGAGACTGTGAGTAGGGCTGGAAGCAGCCTCCAGAAG
AAACGTAAAAAGCGGAAACACCTCAGGAAGAAGCGTGAGGAAGAAGAGGAGGAAGAGGCT
TCTGAGAAAGGGAAGAAGAAAACAGGGGGGAGTAAACAGCAGACAGAGAAGCCAGAGTCG
GAAGATGAGTGGGAACGGACAGAGCGTGAACGCCTTCAGGACCTGGAGGAGCGTGATGCC
TTTGCTGAGCGGGTTCGACAGCGGGACAAGGATCGGACTCGAAATGTCCTGGAACGGTCA
GACAAGAAGGCTTATGAAGAGGCTCAGAAGCGCCTCAAGATGGCCGAGGAAGACCGGAAG
GCCATGATCCCTGAGCTGCGGAAGAAATCTCGCCGAGAGTACCTGGCTAAGCGGGAGCGA
GAGAAGCTTGAGGACCTGGAGGCGGAGCTGGCTGATGAGGAGTTCCTTTTTGGGGACGTG
GAGCTGAGCCGGCACGAGCGGCAGGAGCTCAAATATAAGCGGCGAGTGCGGGATCTCGCC
CGGGAGTACCGGGCAGCTGGGGAGCAGGAGAAGCTGGAGGCCACCAATCGCTACCACATG
CCCAAGGAAACCCGAGGACAGCCAGCCCGAGCTGTGGATCTAGTGGAGGAGGAATCAGGA
GCCCCTGGGGAGGAGCAGCGGCGCTGGGAGGAGGCGCGGCTTGGGGCAGCGTCCCTGAAG
TTTGGGGCCCGAGATGCTGCCTCTCAGGAGCCCAAGTATCAACTGGTGCTGGAGGAGGAG
GAGACCATTGAGTTTGTCCGGGCCACTCAGCTCCAGGGTGATGAGGAGCCGTCAGCTCCA
CCCACTTCAACTCAGGCCCAGCAGAAAGAGTCCATCCAGGCCGTCCGCCGCAGCCTCCCG
GTGTTCCCATTTCGAGAGGAGCTCCTGGCTGCTATTGCAAATCACCAAGTCCTCATCATT
GAAGGCGAGACAGGCTCAGGGAAGACCACCCAGATCCCGCAGTATCTCTTTGAGGAGGGT
TATACAAACAAGGGTATGAAGATTGCCTGCACCCAACCCCGGAGAGTGGCTGCCATGAGT
GTGGCCGCCCGAGTGGCCCGGGAGATGGGTGTGAAGCTTGGGAATGAGGTTGGCTACAGC
ATCCGCTTTGAGGACTGCACATCAGAGCGAACTGTCCTCCGCTACATGACAGATGGGATG
CTTCTCCGGGAGTTCCTCTCTGAGCCTGACCTGGCGAGTTACAGCGTGGTGATGGTGGAT
GAGGCACACGAAAGGACCCTACACACAGACATTCTCTTTGGATTGATCAAGGATGTTGCT
CGCTTCCGACCTGAGCTCAAGGTCCTGGTGGCTTCAGCCACAATGGACACTGCCCGTTTT
TCCACCTTCTTTGATGACGCCCCTGTGTTTCGAATCCCCGGACGCAGGTTTCCTGTGGAC
ATCTTCTACACCAAGGCTCCAGAGGCTGACTACTTGGAAGCTTGTGTAGTATCTGTGTTG
CAGATCCATGTGACCCAGCCCCCTGGGGATATCCTGGTGTTCCTGACAGGACAGGAGGAG
ATTGAGGCTGCCTGTGAGATGCTCCAGGATCCCTGCCGCCGCCTGGGCTCCAAAATCCGG
GAGCTCCTGGTGCTGCCCATTTATGCCAATCTGCCCTCTGACATGCAGGCCCGTATCTTC
CAGCCCACACCACCTGGGGCACGAAAGGTGGTTGTGGCAACGAACATTGCTGAGACATCA
CCCACCATTGAGGGCATCATTTATGTGCTGGATCCAGGGTTCTGTAAGCAGAAGAGCTAC
AACCCCCGCACAGGCATGGAATCGCTCACTGTCACACCCTGCAGCAAGGCCTCAGCCAAT
CAGCGAGCTGGCAGGGCAGGTCGGGTGGCTGCAGGGAAGTGCTTCCGCCTGTATACCGCC
TGGGCCTATCAGCACGAGCTTGAGGAAACCACAGTGCCTGAGATCCAGAGGACCAGCTTG
GGCAATGTCGTGTTGCTGCTCAAGAGCTTAGGGATCCATGACCTAATGCACTTTGATTTC
CTGGACCCTCCACCATATGAGACACTGCTGCTGACTTTGGAGCAGCTGTATGCTCTGGGA
GCCCTCAACCACCTTGGGGAGCTCACCACGTCTGGTCGAAAGATGGCAGAGCTGCCGGTG
GACCCCATGCTGTCCAAAATGATCTTAGCCTCTGAGAAGTACAGCTGTTCAGAGGAGATC
CTGACAGTGGCTGCCATGCTCTCTGTCAACAACTCCATCTTCTACCGACCAAAGGACAAG
GTCGTCCATGCTGACAATGCCCGTGTCAACTTCTTTCTCCCTGGCGGTGACCACCTGGTT
CTGCTAAATGTTTACACACAGTGGGCTGAGAGTGGTTACTCTTCCCAGTGGTGCTGTGAG
AACTTTGTACAGTTCAGATCGATGCGCCGAGCCCGGGATGTGCGGGAACAGCTGGAAGGG
CTCTTGGAACGTGTGGAAGTTGGTCTCAGTTCCTGCCAGGGGGACTATATCCGTGTACGC
AAGGCCATCACTGCTGGTTACTTTTACCACACGGCACGGTTGACTCGGAGTGGCTACCGC
ACAGTGAAACAGCAGCAGACAGTCTTCATTCATCCCAACTCCTCCCTCTTTGAGCAACAG
CCACGCTGGCTGCTCTACCACGAACTTGTCTTGACCACCAAAGAGTTCATGAGACAGGTA
CTGGAGATTGAGAGCAGTTGGCTTCTGGAGGTGGCTCCCCATTATTATAAGGCCAAGGAG
CTAGAAGATCCCCATGCTAAGAAAATGCCCAAAAAAATAGGCAAAACACGAGAAGAGCTA
GGGTAA

Protein Properties

Number of Residues

1041

Molecular Weight

112453.87

Theoretical pI

6.92

Pfam Domain Function

Helicase_C; (PF00271 )
DEAD; (PF00270 )
DUF1605 (PF07717 )
HA2 (PF04408 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16
MATPAGLERWVQDELHSVLGLSERHVAQFLIGTAQRCTSAEEFVQRLRDTDTLDLSGPAR
DFALRLWNKVPRKAVVEKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQK
KRKKRKHLRKKREEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDA
FAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMVPELRKKSRREYLAKRER
EKLEDLEAELADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHM
PKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEE
ETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQAVRRSLPVFPFREELLAAIANHQVLII
EGETGSGKTTQIPQYLFEEGYTNKGMKIACTQPRRVAAMSVAARVAREMGVKLGNEVGYS
IRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVA
RFRPELKVLVASATMDTARFSTFFDDAPVFRIPGRRFPVDIFYTKAPEADYLEACVVSVL
QIHVTQPPGDILVFLTGQEEIEAACEMLQDRCRRLGSKIRELLVLPIYANLPSDMQARIF
QPTPPGARKVVVATNIAETSLTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASAN
QRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDF
LDPPPYETLLLALEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEI
LTVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCYE
NFVQFRSMRRARDVREQLEGLLERVEVGLSSCQGDYIRVRKAITAGYFYHTARLTRSGYR
TVKQQQTVFIHPNSSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYYKAKE
LEDPHAKKMPKKIGKTREELG

External Links

GenBank ID Protein

3107913

UniProtKB/Swiss-Prot ID

O60231

UniProtKB/Swiss-Prot Entry Name

DHX16_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AB001601

GeneCard ID