| Identification |
|---|
| HMDB Protein ID
| CDBP04608 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protein tyrosine phosphatase, receptor type, sigma isoform 3 variant |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| Not Available |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in phosphatase activity |
| Specific Function
| Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate |
| GO Classification
|
| Function |
| phosphoprotein phosphatase activity |
| protein tyrosine phosphatase activity |
| hydrolase activity, acting on ester bonds |
| catalytic activity |
| hydrolase activity |
| phosphoric ester hydrolase activity |
| phosphatase activity |
| Process |
| phosphorus metabolic process |
| phosphate metabolic process |
| dephosphorylation |
| protein amino acid dephosphorylation |
| metabolic process |
| cellular metabolic process |
|
| Cellular Location
|
- Cytoplasmic
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
>4683 bp
CGCTCGGCTCGAGGCCTCTCTGTGAGGGACCGGGGGGCCATCCCCCTCCAGGGCGGAGAT
CGGAGGTCGCTGCCAAGCATGGCGCCCACCTGGGGCCCTGGCATGGTGTCTGTGGTTGGT
CCCATGGGCCTCCTTGTGGTCCTGCTCGTTGGAGGCTGTGCAGCAGAAGAGCCCCCCAGG
TTTATCAAAGAACCCAAGGACCAGATCGGCGTGTCGGGGGGTGTGGCCTCTTTCGTGTGT
CAGGCCACGGGTGACCCCAAGCCACGAGTGACCTGGAACAAGAAGGGCAAGAAGGTCAAC
TCTCAGCGCTTTGAGACGATTGAGTTTGATGAGAGTGCAGGGGCAGTGCTGAGGATCCAG
CCGCTGAGGACACCGCGGGATGAAAACGTGTACGAGTGTGTGGCCCAGAACTCGGTTGGG
GAGATCACAGTCCATGCCAAGCTTACTGTCCTCCGAGAGGACCAGCTGCCCTCTGGCTTC
CCCAACATCGACATGGGCCCACAGTTGAAGGTGGTGGAGCGGACACGGACAGCCACCATG
CTCTGTGCAGCCAGCGGCAACCCTGACCCTGAGATCACCTGGTTCAAGGACTTCCTGCCT
GTGGATCCTAGTGCCAGCAATGGACGCATCAAACAGCTGCGATCAGGAGCCCTGCAGATT
GAAAGCAGTGAGGAAACCGACCAGGGCAAATATGAGTGTGTGGCCACCAACAGCGCCGGC
GTGCGCTACTCCTCACCTGCCAACCTCTACGTGCGAGTCCGCCGCGTGGCCCCGCGCTTC
TCCATCCTGCCCATGAGCCACGAGATCATGCCAGGGGGCAACGTGAACATCACCTGCGTG
GCCGTGGGCTCGCCCATGCCATACGTGAAGTGGATGCAGGGGGCCGAGGACCTGACCCCC
GAGGATGACATGCCCGTGGGTCGGAACGTGCTGGAACTCACAGATGTCAAGGACTCGGCC
AACTACACCTGCGTGGCCATGTCCAGCCTGGGCGTCATTGAGGCGGTTGCTCAGATCACG
GTGAAATCTCTCCCCAAAGCTCCCGGGACTCCCATGGTGACTGAGAACACAGCCACCAGC
ATCACCATCACGTGGGACTCGGGCAACCCAGATCCTGTGTCCTATTACGTCATCGAATAT
AAATCCAAGAGCCAAGACGGGCCGTATCAGATTAAAGAGGACATCACCACCACACGTTAC
AGCATCGGCGGCCTGAGCCCCAACTCGGAGTACGAGATCTGGGTGTCGGCCGTCAACTCC
ATCGGCCAGGGGCCCCCCAGCGAGTCCGTGGTCACCCGCACAGGCGAGCAGGCCCCGGCC
AGCGCGCCGCGGAACGTGCAAGCCCGGATGCTCAGCGCGACCACCATGATTGTGCAGTGG
GAGGAGCCGGTGGAGCCCAACGGCCTGATCCGCGGCTACCGCGTCTACTACACCATGGAA
CCGGAGCACCCCGTGGGCAACTGGCAGAAGCACAACGTGGACGACAGCCTGCTGACCACC
GTGGGCAGCCTGCTGGAGGACGAGACCTACACCGTGCGGGTGCTCGCCTTCACCTCCGTC
GGCGACGGGCCCCTCTCGGACCCCATCCAGGTCAAGACGCAGCAGGGAGTGCCGGGCCAG
CCCATGAACCTGCGGGCCGAGGCCAGGTCGGAGACCAGCATCACGCTGTCCTGGAGCCCC
CCGCGGCAGGAGAGTATCATCAAGTACGAGCTCCTCTTCCGGGAAGGCGACCATGGCCGG
GAGGTGGGAAGGACCTTCGACCCGACGACTTCCTACGTGGTGGAGGACCTGAAGCCCAAC
ACGGAGTACGCCTTCCGCCTGGCGGCCCGCTCGCCGCAGGGCCTGGGCGCCTTCACCCCC
GTGGTGCGGCAGCGCACGCTGCAGTCCATCTCGCCCAAGAACTTCAAGGTGAAAATGATC
ATGAAGACATCAGTTCTGCTCAGCTGGGAGTTCCCTGACAACTACAACTCACCCACACCC
TACAAGATCCAGTACAATGGGCTCACACTGGATGTGGATGGCCGTACCACCAAGAAGCTC
ATCACGCACCTCAAGCCCCACACCTTCTACAACTTTGTGCTGACCAATCGCGGCAGCAGC
CTGGGCGGCCTCCAGCAGACGGTCACCGCCTGGACTGCCTTCAACCTGCTCAACGGCAAG
CCCAGCGTCGCCCCCAAGCCTGATGCTGACGGCTTCATCATGGTGTATCTTCCTGACGGC
CAGAGCCCCGTGCCTGTCCAGAGCTATTTCATTGTGATGGTGCCACTGCGCAAGTCTCGT
GGAGGCCAATTCCTGACCCCGCTGGGTAGCCCAGAGGACATGGATCTGGAAGAGCTCATC
CAGGACATCTCACGGCTACAGAGGCGCAGCCTGCGGCACTCGCGTCAGCTGGAGGTGCCC
CGGCCCTATATTGCAGCTCGCTTCTCTGTGCTGCCACCCACGTTCCATCCCGGCGACCAG
AAGCAGTATGGCGGCTTCGATAACCGGGGCCTGGAGCCCGGCCACCGCTATGTCCTCTTC
GTGCTTGCCGTGCTTCAGAAGAGCGAGCCTACCTTTGCAGCCAGTCCCTTCTCAGACCCC
TTCCAGCTGGATAACCCGGACCCCCAGCCCATCGTGGATGGCGAGGAGGGGCTTATCTGG
GTGATCGGGCCTGTGCTGGCCGTGGTCTTCATAATCTGCATTGTCATTGCTATCCTGCTC
TACAAGAACAAACCCGACAGTAAACGCAAGGACTCAGAACCCCGCACCAAATGCCTCCTG
AACAATGCCGACCTCGCCCCTCACCACCCCAAGGACCCTGTGGAAATGAGACGCATTAAC
TTCCAGACTCCAGATTCAGGCCTCAGGAGCCCCCTCAGGGAGCCGGGGTTTCACTTTGAA
AGCATGCTTAGCCACCCGCCAATTCCCATCGCAGACATGGCGGAGCACACGGAGCGGCTC
AAGGCCAACGACAGCCTCAAGCTCTCCCAGGAGTATGAGTCCATCGACCCTGGACAGCAG
TTCACATGGGAACATTCCAACCTGGAAGTGAACAAGCCGAAGAACCGCTATGCCAACGTC
ATCGCCTATGACCACTCCCGTGTCATCCTCCAGCCCATTGAAGGCATCATGGGCAGTGAT
TACATCAATGCCAACTACGTGGACGGCTACCGGCGTCAGAACGCGTACATTGCCACGCAG
GGGCCGCTGCCTGAGACCTTTGGGGACTTCTGGCGTATGGTGTGGGAGCAGCGGTCGGCG
ACCATCGTCATGATGACGCGGCTGGAGGAGAAGTCACGGATCAAGTGTGATCAGTATTGG
CCCAACAGAGGCACGGAGACCTACGGCTTCATCCAGGTCACGTTGCTAGATACCATCGAG
CTGGCCACATTCTGCGTCAGGACATTCTCTCTGCACAAGAATGGCTCCAGTGAGAAACGC
GAGGTCCGCCAGTTCCAGTTTACGGCGTGGCCGGACCATGGCGTGCCCGAATACCCAACG
CCCTTCCTGGCTTTCCTGCGGAGAGTCAAGACCTGCAACCCACCAGATGCCGGCCCCATC
GTGGTTCACTGCAGTGCCGGTGTGGGCCGCACAGGCTGCTTTATCGTCATCGACGCCATG
CTTGAGCGGATCAAGCCAGAGAAGACAGTCGATGTCTATGGCCACGTGACGCTCATGAGG
TCCCAGCGCAACTACATGGTGCAGACGGAGGACCAGTACAGCTTCATCCACGAGGCCCTG
CTGGAGGCCGTGGGCTGTGGCAACACAGAAGTGCCCGCACGCAGCCTCTATGCCTACATC
CAGAAGCTGGCCCAGGTGGAGCCTGGCGAACACGTCACTGGCATGGAACTCGAGTTCAAG
CGGCTGGCTAACTCCAAGGCCCACACGTCACGCTTCATCAGTGCCAATCTGCCTTGTAAC
AAGTTCAAGAACCGCCTGGTGAACATCATGCCCTATGAGAGCACACGGGTCTGTCTGCAA
CCCATCCGGGGTGTGGAGGGCTCTGACTACATCAACGCCAGCTTCATTGATGGCTACAGG
CAGCAGAAGGCCTACATCGCGACACAGGGGCCGCTGGCGGAGACCACGGAAGACTTCTGG
CGCATGCTGTGGGAGAACAATTCGACGATCGTGGTGATGCTGACCAAGCTGCGGGAGATG
GGCCGGGAGAAGTGTCACCAGTACTGGCCGGCCGAGCGCTCTGCCCGCTACCAGTACTTT
GTGGTAGATCCGATGGCAGAATACAACATGCCTCAGTATATCCTGCGAGAGTTCAAGGTC
ACAGATGCCCGGGATGGCCAGTCCCGGACTGTCCGGCAGTTCCAGTTCACAGACTGGCCG
GAACAGGGTGTGCCAAAGTCGGGGGAGGGCTTCATCGACTTCATTGGCCAAGTGCATAAG
ACTAAGGAGCAGTTTGGCCAGGACGGCCCCATCTCTGTCCACTGCAGTGCCGGCGTGGGC
AGGACGGGCGTCTTCATCACGCTTAGCATCGTGCTGGAGCGGATGCGGTATGAAGGCGTG
GTGGACATCTTTCAGACGGTGAAGATGCTACGAACCCAGCGGCCGGCCATGGTGCAGACA
GAGACGGAGTCTCGCCCAGGCTGGAGTGCAGTGGCTCAATCTCGGCTCACTGCAAGCTCC
GCCTCCCGGATCCACGCCATTCTCCTGCCTCAGCCTCCCGAGTGGCTGGGACTACAGGAT
TGA
|
| Protein Properties |
|---|
| Number of Residues
| 1560 |
| Molecular Weight
| 174654.5 |
| Theoretical pI
| 7.02 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protein tyrosine phosphatase, receptor type, sigma isoform 3 variant
RSARGLSVRDRGAIPLQGGDRRSLPSMAPTWGPGMVSVVGPMGLLVVLLVGGCAAEEPPR
FIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLRIQ
PLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATM
LCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAG
VRYSSPANLYVRVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTP
EDDMPVGRNVLELTDVKDSANYTCVAMSSLGVIEAVAQITVKSLPKAPGTPMVTENTATS
ITITWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNS
IGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTME
PEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQ
PMNLRAEARSETSITLSWSPPRQESIIKYELLFREGDHGREVGRTFDPTTSYVVEDLKPN
TEYAFRLAARSPQGLGAFTPVVRQRTLQSISPKNFKVKMIMKTSVLLSWEFPDNYNSPTP
YKIQYNGLTLDVDGRTTKKLITHLKPHTFYNFVLTNRGSSLGGLQQTVTAWTAFNLLNGK
PSVAPKPDADGFIMVYLPDGQSPVPVQSYFIVMVPLRKSRGGQFLTPLGSPEDMDLEELI
QDISRLQRRSLRHSRQLEVPRPYIAARFSVLPPTFHPGDQKQYGGFDNRGLEPGHRYVLF
VLAVLQKSEPTFAASPFSDPFQLDNPDPQPIVDGEEGLIWVIGPVLAVVFIICIVIAILL
YKNKPDSKRKDSEPRTKCLLNNADLAPHHPKDPVEMRRINFQTPDSGLRSPLREPGFHFE
SMLSHPPIPIADMAEHTERLKANDSLKLSQEYESIDPGQQFTWEHSNLEVNKPKNRYANV
IAYDHSRVILQPIEGIMGSDYINANYVDGYRRQNAYIATQGPLPETFGDFWRMVWEQRSA
TIVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKR
EVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAM
LERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYI
QKLAQVEPGEHVTGMELEFKRLANSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQ
PIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREM
GREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWP
EQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGV
VDIFQTVKMLRTQRPAMVQTETESRPGWSAVAQSRLTASSASRIHAILLPQPPEWLGLQD
|
| External Links |
|---|
| GenBank ID Protein
| 62088246 |
| UniProtKB/Swiss-Prot ID
| Q59FX6 |
| UniProtKB/Swiss-Prot Entry Name
| Q59FX6_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AB209333 |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| HGNC:9681 |
| References |
|---|
| General References
| Not Available |