| Identification |
|---|
| HMDB Protein ID
| CDBP04593 |
| Secondary Accession Numbers
| Not Available |
| Name
| Mast cell carboxypeptidase A |
| Description
| Not Available |
| Synonyms
|
- Carboxypeptidase A3
- MC-CPA
|
| Gene Name
| CPA3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in metallocarboxypeptidase activity |
| Specific Function
| Release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro |
| GO Classification
|
| Function |
| binding |
| catalytic activity |
| hydrolase activity |
| transition metal ion binding |
| zinc ion binding |
| metallocarboxypeptidase activity |
| carboxypeptidase activity |
| peptidase activity |
| peptidase activity, acting on l-amino acid peptides |
| exopeptidase activity |
| ion binding |
| cation binding |
| metal ion binding |
| Process |
| metabolic process |
| macromolecule metabolic process |
| protein metabolic process |
| proteolysis |
|
| Cellular Location
|
- Cytoplasmic vesicle
- secretory vesicle
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:3 |
| Locus
| 3q21-q25 |
| SNPs
| CPA3 |
| Gene Sequence
|
>1254 bp
ATGAGGCTCATCCTGCCTGTGGGTTTGATTGCTACCACTCTTGCAATTGCTCCTGTCCGC
TTTGACAGGGAGAAGGTGTTCCGCGTGAAGCCCCAGGATGAAAAACAAGCAGACATCATA
AAGGACTTGGCCAAAACCAATGAGCTTGACTTCTGGTATCCAGGTGCCACCCACCACGTA
GCTGCTAATATGATGGTGGATTTCCGAGTTAGTGAGAAGGAATCCCAAGCCATCCAGTCT
GCCTTGGATCAAAATAAAATGCACTATGAAATCTTGATTCATGATCTACAAGAAGAGATT
GAGAAACAGTTTGATGTTAAAGAAGATATCCCAGGCAGGCACAGCTACGCAAAATACAAT
AATTGGGAAAAGATTGTGGCTTGGACTGAAAAGATGATGGATAAGTATCCTGAAATGGTC
TCTCGTATTAAAATTGGATCTACTGTTGAAGATAATCCACTATATGTTCTGAAGATTGGG
GAAAAGAATGAAAGAAGAAAGGCTATTTTTACGGATTGTGGCATTCACGCACGAGAATGG
GTCTCCCCAGCATTCTGCCAGTGGTTTGTCTATCAGGCAACCAAAACTTATGGGAGAAAC
AAAATTATGACCAAACTCTTGGACCGAATGAATTTTTACATTCTTCCTGTGTTCAATGTT
GATGGATATATTTGGTCATGGACAAAGAACCGCATGTGGAGAAAAAATCGTTCCAAGAAC
CAAAACTCCAAATGCATCGGCACTGACCTCAACAGGAATTTTAATGCTTCATGGAACTCC
ATTCCTAACACCAATGACCCATGTGCAGATAACTATCGGGGCTCTGCACCAGAGTCCGAG
AAAGAGACGAAAGCTGTCACTAATTTCATTAGAAGCCACCTGAATGAAATCAAGGTTTAC
ATCACCTTCCATTCCTACTCCCAGATGCTATTGTTTCCCTATGGATATACATCAAAACTG
CCACCTAACCATGAGGACTTGGCCAAAGTTGCAAAGATTGGCACTGATGTTCTATCAACT
CGATATGAAACCCGCTACATCTATGGCCCAATAGAATCAACAATTTACCCGATATCAGGT
TCTTCTTTAGACTGGGCTTATGACCTGGGCATCAAACACACATTTGCCTTTGAGCTCCGA
GATAAAGGCAAATTTGGTTTTCTCCTTCCAGAATCCCGGATAAAGCCAACGTGCAGAGAG
ACCATGCTAGCTGTCAAATTTATTGCCAAGTATATCCTCAAGCATACTTCCTAA
|
| Protein Properties |
|---|
| Number of Residues
| 417 |
| Molecular Weight
| 48699.5 |
| Theoretical pI
| 9.38 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Mast cell carboxypeptidase A
MRLILPVGLIATTLAIAPVRFDREKVFRVKPQDEKQADIIKDLAKTNELDFWYPGATHHV
AANMMVDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVKEDIPGRHSYAKYN
NWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKAIFMDCGIHAREW
VSPAFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKNRSKN
QNSKCIGTDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLNEIKVY
ITFHSYSQMLLFPYGYTSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYGPIESTIYPISG
SSLDWAYDLGIKHTFAFELRDKGKFGFLLPESRIKPTCRETMLAVKFIAKYILKHTS
|
| External Links |
|---|
| GenBank ID Protein
| 221316749 |
| UniProtKB/Swiss-Prot ID
| P15088 |
| UniProtKB/Swiss-Prot Entry Name
| CBPA3_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_001870.2 |
| GeneCard ID
| CPA3 |
| GenAtlas ID
| CPA3 |
| HGNC ID
| HGNC:2298 |
| References |
|---|
| General References
| Not Available |