| Identification |
| HMDB Protein ID
| CDBP04581 |
| Secondary Accession Numbers
| Not Available |
| Name
| Vacuolar-type H(+)-ATPase |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| Not Available |
| Protein Type
| Enzyme |
| Biological Properties |
| General Function
| Involved in hydrogen ion transmembrane transporter activity |
| Specific Function
| Not Available |
| GO Classification
|
| Component |
| proton-transporting two-sector atpase complex, proton-transporting domain |
| macromolecular complex |
| protein complex |
| Function |
| transmembrane transporter activity |
| substrate-specific transmembrane transporter activity |
| ion transmembrane transporter activity |
| cation transmembrane transporter activity |
| inorganic cation transmembrane transporter activity |
| monovalent inorganic cation transmembrane transporter activity |
| hydrogen ion transmembrane transporter activity |
| transporter activity |
| Process |
| nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
| nucleobase, nucleoside and nucleotide metabolic process |
| nucleoside phosphate metabolic process |
| nucleotide metabolic process |
| atp synthesis coupled proton transport |
| atp biosynthetic process |
| purine nucleotide metabolic process |
| purine nucleotide biosynthetic process |
| purine nucleoside triphosphate biosynthetic process |
| purine ribonucleoside triphosphate biosynthetic process |
| metabolic process |
| nitrogen compound metabolic process |
| cellular nitrogen compound metabolic process |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
>2496 bp
ATGGGGGAGCTTTTCCGGAGTGAAGAAATGACACTGGCCCAGCTTTTTCTACAGTCAGAG
GCTGCTTATTGTTGTGTCAGTGAATTAGGAGAACTTGGAAAGGTTCAGTTTCGTGACTTA
AATCCAGATGTGAATGTTTTCCAACGGAAATTTGTGAATGAAGTTAGAAGATGTGAAGAA
ATGGATCGAAAGCTTCGATTTGTTGAGAAAGAGATAAGAAAAGCTAACATTCCGATTATG
GACACCGGTGAAAACCCAGAGGTTCCCTTCCCCCGGGACATGATCGACTTAGAGGCCAAT
TTTGAGAAGATTGAAAATGAACTGAAGGAAATCAACACAAACCAGGAAGCTCTGAAGAGA
AACTTCCTGGAACTGACCGAATTAAAATTTATACTTCGCAAAACTCAGCAATTTTTTGAT
GAGATGGCGGATCCAGACTTGTTGGAAGAGTCCTCATCCCTCTTGGAGCCAAGTGAGATG
GGAAGAGGCACTCCTTTAAGACTTGGCTTCGTGGCTGGTGTCATTAACCGGGAGCGCATC
CCTACTTTTGAGCGCATGCTTTGGCGGGTATGCCGGGGAAATGTGTTCCTGCGACAGGCT
GAAATCGAGAACCCCCTGGAGGATCCTGTGACTGGCGACTACGTGCACAAGTCTGTGTTT
ATCATTTTCTTCCAAGGCGATCAGCTGAAAAACAGAGTCAAGAAAATCTGTGAAGGGTTC
CGAGCCTCACTCTATCCCTGTCCTGAGACACCACAGGAGAGGAAGGAAATGGCTTCTGGA
GTGAATACCAGGATTGATGATCTCCAAATGGTTCTGAATCAAACGGAGGATCACCGCCAG
AGGGTTCTGCAGGCAGCTGCTAAGAACATCCGTGTCTGGTTCATCAAAGTGCGGAAGATG
AAGGCCATCTATCACACCCTGAACCTGTGCAACATAGATGTGACTCAGAAATGCTTGATT
GCAGAGGTCTGGTGCCCTGTCACCGACCTTGACTCCATCCAGTTTGCACTCAGAAGGGGC
ACGGAACACAGTGGTTCCACTGTACCTTCCATTTTGAACAGGATGCAGACAAACCAGACT
CCCCCAACCTATAACAAAACCAACAAGTTTACCTATGGCTTTCAGAACATAGTAGATGCT
TATGGAATTGGAACTTACCGAGAGATAAATCCAGCTCCGTATACTATTATCACGTTCCCT
TTTCTATTTGCTGTGATGTTTGGAGACTTCGGTCATGGCATTTTAATGACCCTTTTTGCT
GTGTGGATGGTACTGAGGGAGAGCCGGATCCTTTCCCAGAAGAATGAGAATGAGATGTTT
AGCACTGTGTTCAGTGGTCGATACATTATTTTATTGATGGGTGTGTTCTCCATGTACACT
GGCCTCATCTACAATGATTGCTTTTCCAAGTCTCTTAATATCTTTGGGTCATCCTGGAGT
GTACGGCCGATGTTTACTTATAATTGGACTGAAGAGACGCTTCGGGGGAACCCTGTTCTA
CAGCTGAACCCAGCCCTCCCTGGAGTGTTTGGTGGACCATACCCTTTTGGCATTGATCCA
ATTTGGAACATTGCTACCAATAAACTGACGTTCTTGAACTCCTTTAAGATGAAGATGTCT
GTTATCCTTGGTATCATCCATATGCTGTTTGGAGTCAGCCTGAGTCTGTTCAACCATATC
TATTTCAAGAAGCCCCTGAATATCTACTTTGGATTTATTCCTGAAATAATCTTCATGACC
TCTTTGTTTGGCTATTTGGTTATCCTTATTTTTTACAAGTGGACGGCCTATGATGCTCAT
ACCTCTGAGAATGCACCAAGCCTTCTGATCCATTTCATAAACATGTTCCTCTTTTCCTAC
CCAGAGTCTGGTTATTCAATGTTGTATTCTGGACAGAAAGGAATTCAGTGTTTCCTGGTA
GTGGTTGCACTACTGTGTGTACCTTGGATGCTGCTGTTTAAACCATTGGTCCTTCGCCGT
CAGTATTTGAGGAGAAAGCATTTGGGAACTCTCAACTTTGGTGGGATCAGGGTGGGCAAC
GGACCGACAGAGGAGGATGCTGAGATTATTCAGCATGACCAGCTCTCCACCCACTCAGAG
GACGCAGACGAGTTTGACTTTGGGGACACCATGGTCCACCAGGCCATCCACACCATCGAG
TACTGCCTGGGCTGCATCTCCAACACTGCCTCCTACTTGCGGCTCTGGGCCCTCAGCCTC
GCTCATGCGCACGTGTCTGAGGTGCTTTGGACCATGGTGATCCACATCGGCCTGAGCGTG
AAGAGCTTGGCGGGAGGTTTGGTGCTGTTCTTCTTCTTCACTGCCTTTGCCACCCTGACC
GTGGCCATCCTCCTGATCATGGAGGGCCTCTCGGCCTTTCTCCACGCACTGCGCTTACAC
TGGGTTGAGTTCCAGAATAAATTCTACAGCGGGACCGGTTTCAAGTTCTTACCCTTCTCC
TTCGAGCATATTCGGGAAGGGAAGTTTGAAGAGTGA
|
| Protein Properties |
| Number of Residues
| 831 |
| Molecular Weight
| 95750.3 |
| Theoretical pI
| 6.67 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Vacuolar-type H(+)-ATPase
MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEE
MDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKR
NFLELTELKFILRKTQQFFDEMADPDLLEESSSLLEPSEMGRGTPLRLGFVAGVINRERI
PTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRVKKICEGF
RASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVWFIKVRKM
KAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILNRMQTNQT
PPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHGILMTLFA
VWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMYTGLIYNDCFSKSLNIFGSSWS
VRPMFTYNWTEETLRGNPVLQLNPALPGVFGGPYPFGIDPIWNIATNKLTFLNSFKMKMS
VILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMTSLFGYLVILIFYKWTAYDAH
TSENAPSLLIHFINMFLFSYPESGYSMLYSGQKGIQCFLVVVALLCVPWMLLFKPLVLRR
QYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDADEFDFGDTMVHQAIHTIE
YCLGCISNTASYLRLWALSLAHAHVSEVLWTMVIHIGLSVKSLAGGLVLFFFFTAFATLT
VAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHIREGKFEE
|
| External Links |
| GenBank ID Protein
| 18653904 |
| UniProtKB/Swiss-Prot ID
| Q53X12 |
| UniProtKB/Swiss-Prot Entry Name
| Q53X12_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| L78933 |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| HGNC:865 |
| References |
| General References
| Not Available |