| Identification |
| HMDB Protein ID
| CDBP04570 |
| Secondary Accession Numbers
| Not Available |
| Name
| Cyclin-dependent kinase-like 3 |
| Description
| Not Available |
| Synonyms
|
- Serine/threonine-protein kinase NKIAMRE
|
| Gene Name
| CDKL3 |
| Protein Type
| Enzyme |
| Biological Properties |
| General Function
| Involved in protein kinase activity |
| Specific Function
| ATP + a protein = ADP + a phosphoprotein |
| GO Classification
|
| Function |
| transferase activity, transferring phosphorus-containing groups |
| kinase activity |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| adenyl ribonucleotide binding |
| atp binding |
| protein kinase activity |
| protein serine/threonine kinase activity |
| binding |
| catalytic activity |
| transferase activity |
| Process |
| phosphorus metabolic process |
| phosphate metabolic process |
| metabolic process |
| cellular metabolic process |
| protein amino acid phosphorylation |
| phosphorylation |
|
| Cellular Location
|
- Cytoplasm
|
| Pathways
|
Not Available
|
| Gene Properties |
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q31 |
| SNPs
| CDKL3 |
| Gene Sequence
|
>1779 bp
ATGGAGATGTATGAAACCCTTGGAAAAGTGGGAGAGGGAAGTTACGGAACAGTCATGAAA
TGTAAACATAAGAATACTGGGCAGATAGTGGCCATTAAGATATTTTATGAGAGACCAGAA
CAATCTGTCAACAAAATTGCGATGAGAGAAATAAAGTTTCTAAAGCAATTTCATCACGAA
AACCTGGTCAATCTGATTGAAGTTTTTAGACAGAAAAAGAAAATTCATTTGGTATTTGAA
TTTATTGACCACACAGTATTAGATGAGTTACAACATTATTGTCATGGACTAGAGAGTAAG
CGACTTAGAAAATACCTCTTCCAGATCCTTCGAGCAATTGACTATCTTCACAGTAATAAT
ATCATTCATCGAGATATAAAACCTGAGAATATTTTAGTATCCCAGTCAGGAATTACTAAG
CTCTGTGATTTTGGTTTTGCACGAACACTAGCAGCTCCTGGGGACATTTATACGGACTAT
GTGGCCACACGCTGGTATAGAGCTCCCGAATTAGTATTAAAAGATACTTCTTATGGAAAA
CCTGTGGATATCTGGGCTTTGGGCTGTATGATCATTGAGATGGCCACTGGAAATCCCTAT
CTTCCTAGTAGTTCTGATTTGGATTTACTCCATAAAATTGTTTTGAAAGTGGGCAATTTG
TCACCTCACTTGCAGAATATCTTTTCCAAGAGCCCCATTTTTGCTGGGGTAGTTCTTCCT
CAAGTTCAACACCCCAAAAATGCAAGAAAAAAATATCCAAAGCTTAATGGATTGTTGGCA
GATATAGTTCATGCTTGTTTACAAATTGATCCTGCTGACAGGATATCATCTAGTGATCTT
TTGCATCATGAGTATTTTACTAGAGATGGATTTATTGAAAAATTCATGCCAGAACTGAAA
GCTAAATTACTGCAGGAAGCAAAAGTCAATTCATTAATAAAGCCAAAAGAGAGTTCTAAA
GAAAATGAACTCAGGAAAGATGAAAGAAAAACAGTTTATACCAATACACTGCTAAGTAGT
TCAGTTTTGGGAAAGGAAATAGAAAAAGAGAAAAAGCCCAAGGAGATCAAAGTCAGAGTT
ATTAAAGTCAAAGGAGGAAGAGGAGATATCTCAGAACCAAAAAAGAAAGAGTATGAAGGT
GGACTTGGTCAACAGGATGCAAATGAAAATGTTCATCCTATGTCTCCAGATACAAAACTT
GTAACCATTGAACCACCAAACCCTATCAATCCCAGCACTAACTGTAATGGCTTGAAAGAA
AATCCACATTGCGGAGGTTCTGTGACAATGCCACCCATCAATCTAACTAACAGTAATTTG
ATGGCTGCAAATCTCAGTTCAAATCTCTTTCACCCCAGTGTGAGGTTAACTGAAAGAGCA
AAAAAGAGACGCACTTCTTCACAATCTATTGGACAAGTTATGCCTAATAGCAGGCAAGAG
GATCCAGGTCCTATTCAAAGCCAAATGGAGAAGGGTATATTTAATGAGCGAACAGGTCAC
AGTGACCAAATGGCAAATGAGAACAAAAGGAAGCTGAATTTTTCCAGATCTGACAGGAAA
GAATTCCATTTTCCAGAATTGCCTGTCACAATACAGTCAAAAGATACAAAAGGAATGGAA
GTTAAACAGATAAAAATGCTGAAGAGGGAGTCAAAGAAAACAGAGTCATCTAAGATACCA
ACTTTACTTAACGTGGATCAAAATCAAGAAAAACAAGAGGGTGGAGATGGCCATTGCGAG
GGGAAGAATTTGAAGAGAAACAGGTTTTTTTTCTGGTAG
|
| Protein Properties |
| Number of Residues
| 592 |
| Molecular Weight
| 67513.3 |
| Theoretical pI
| 9.88 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Cyclin-dependent kinase-like 3
MEMYETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQSVNKIAMREIKFLKQFHHE
NLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSNN
IIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYGK
PVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKSPIFAGVVLP
QVQHPKNARKKYPKLNGLLADIVHACLQIDPADRISSSDLLHHEYFTRDGFIEKFMPELK
AKLLQEAKVNSLIKPKESSKENELRKDERKTVYTNTLLSSSVLGKEIEKEKKPKEIKVRV
IKVKGGRGDISEPKKKEYEGGLGQQDANENVHPMSPDTKLVTIEPPNPINPSTNCNGLKE
NPHCGGSVTMPPINLTNSNLMAANLSSNLFHPSVRLTERAKKRRTSSQSIGQVMPNSRQE
DPGPIQSQMEKGIFNERTGHSDQMANENKRKLNFSRSDRKEFHFPELPVTIQSKDTKGME
VKQIKMLKRESKKTESSKIPTLLNVDQNQEKQEGGDGHCEGKNLKRNRFFFW
|
| External Links |
| GenBank ID Protein
| 166064027 |
| UniProtKB/Swiss-Prot ID
| Q8IVW4 |
| UniProtKB/Swiss-Prot Entry Name
| CDKL3_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_001113575.1 |
| GeneCard ID
| CDKL3 |
| GenAtlas ID
| CDKL3 |
| HGNC ID
| HGNC:15483 |
| References |
| General References
| Not Available |