Cannabis Compound Database: Showing Protein G protein-coupled receptor kinase 7 (CDBP04566)

Identification Biological properties Gene properties Protein properties External links References XML Show 2 compounds

Identification

HMDB Protein ID

CDBP04566

Secondary Accession Numbers

Not Available

Name

G protein-coupled receptor kinase 7

Description

Not Available

Synonyms

G protein-coupled receptor kinase GRK7

Gene Name

GRK7

Protein Type

Enzyme

Biological Properties

General Function

Involved in protein serine/threonine kinase activity

Specific Function

Phosphorylates cone opsins thereby initiating their deactivation

GO Classification

Function
adenyl ribonucleotide binding
atp binding
g-protein coupled receptor kinase activity
molecular transducer activity
signal transducer activity
protein kinase activity
protein serine/threonine kinase activity
binding
catalytic activity
transferase activity
transferase activity, transferring phosphorus-containing groups
kinase activity
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
Process
phosphorylation
phosphorus metabolic process
phosphate metabolic process
metabolic process
biological regulation
regulation of biological process
cellular metabolic process
regulation of cellular process
signal transduction
protein amino acid phosphorylation

Cellular Location

Lipid-anchor
Membrane

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:3

Locus

3q24

SNPs

GRK7

Gene Sequence

>1662 bp
ATGGTGGACATGGGGGCCCTGGACAACCTGATCGCCAACACCGCCTACCTGCAGGCCCGG
AAGCCCTCGGACTGCGACAGCAAAGAGCTGCAGCGGCGGCGGCGTAGCCTGGCCCTGCCC
GGGCTGCAGGGCTGCGCGGAGCTCCGCCAGAAGCTGTCCCTGAACTTCCACAGCCTGTGT
GAGCAGCAGCCCATCGGTCGCCGCCTCTTCCGTGACTTCCTAGCCACAGTGCCCACGTTC
CGCAAGGCGGCAACCTTCCTAGAGGACGTGCAGAACTGGGAGCTGGCCGAGGAGGGACCC
ACCAAAGACAGCGCGCTGCAGGGGCTGGTGGCCACTTGTGCGAGTGCCCCTGCCCCGGGG
AACCCGCAACCCTTCCTCAGCCAGGCCGTGGCCACCAAGTGCCAAGCAGCCACCACTGAG
GAAGAGCGAGTGGCTGCAGTGACGCTGGCCAAGGCTGAGGCCATGGCTTTCTTGCAAGAG
CAGCCCTTTAAGGATTTCGTGACCAGCGCCTTCTACGACAAGTTTCTGCAGTGGAAACTC
TTCGAGATGCAACCAGTGTCAGACAAGTACTTCACTGAGTTCAGAGTGCTGGGGAAAGGT
GGTTTTGGGGAGGTATGTGCCGTCCAGGTGAAAAACACTGGGAAGATGTATGCCTGTAAG
AAACTGGACAAGAAGCGGCTGAAGAAGAAAGGTGGCGAGAAGATGGCTCTCTTGGAAAAG
GAAATCTTGGAGAAGGTCAGCAGCCCTTTCATTGTCTCTCTGGCCTATGCCTTTGAGAGC
AAGACCCATCTCTGCCTTGTCATGAGCCTGATGAATGGGGGAGACCTCAAGTTCCACATC
TACAACGTGGGCACGCGTGGCCTGGACATGAGCCGGGTGATCTTTTACTCGGCCCAGATA
GCCTGTGGGATGCTGCACCTCCATGAACTCGGCATCGTCTATCGGGACATGAAGCCTGAG
AATGTGCTTCTGGATGACCTCGGCAACTGCAGGTTATCTGACCTGGGGCTGGCCGTGGAG
ATGAAGGGTGGCAAGCCCATCACCCAGAGGGCTGGAACCAATGGTTACATGGCTCCTGAG
ATCCTAATGGAAAAGGTAAGTTATTCCTATCCTGTGGACTGGTTTGCCATGGGATGCAGC
ATTTATGAAATGGTTGCTGGACGAACACCATTCAAAGATTACAAGGAAAAGGTCAGTAAA
GAGGATCTGAAGCAAAGAACTCTGCAAGACGAGGTCAAATTCCAGCATGATAACTTCACA
GAGGAAGCAAAAGATATTTGCAGGCTCTTCTTGGCTAAGAAACCAGAGCAACGCTTAGGA
AGCAGAGAAAAGTCTGATGATCCCAGGAAACATCATTTCTTTAAAACGATCAACTTTCCT
CGCCTGGAAGCTGGCCTAATTGAACCCCCATTTGTGCCAGACCCTTCAGTGGTTTATGCC
AAAGACATCGCTGAAATTGATGATTTCTCTGAGGTTCGGGGGGTGGAATTTGATGACAAA
GATAAGCAGTTCTTCAAAAACTTTGCGACAGGTGCTGTTCCTATAGCATGGCAGGAAGAA
ATTATAGAAACGGGACTGTTTGAGGAACTGAATGACCCCAACAGACCTACGGGTTGTGAG
GAGGGTAATTCATCCAAGTCTGGCGTGTGTTTGTTATTGTAA

Protein Properties

Number of Residues

553

Molecular Weight

62211.0

Theoretical pI

6.52

Pfam Domain Function

Pkinase (PF00069 )
RGS (PF00615 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>G protein-coupled receptor kinase 7
MVDMGALDNLIANTAYLQARKPSDCDSKELQRRRRSLALPGLQGCAELRQKLSLNFHSLC
EQQPIGRRLFRDFLATVPTFRKAATFLEDVQNWELAEEGPTKDSALQGLVATCASAPAPG
NPQPFLSQAVATKCQAATTEEERVAAVTLAKAEAMAFLQEQPFKDFVTSAFYDKFLQWKL
FEMQPVSDKYFTEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKGGEKMALLEK
EILEKVSSPFIVSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVGTRGLDMSRVIFYSAQI
ACGMLHLHELGIVYRDMKPENVLLDDLGNCRLSDLGLAVEMKGGKPITQRAGTNGYMAPE
ILMEKVSYSYPVDWFAMGCSIYEMVAGRTPFKDYKEKVSKEDLKQRTLQDEVKFQHDNFT
EEAKDICRLFLAKKPEQRLGSREKSDDPRKHHFFKTINFPRLEAGLIEPPFVPDPSVVYA
KDIAEIDDFSEVRGVEFDDKDKQFFKNFATGAVPIAWQEEIIETGLFEELNDPNRPTGCE
EGNSSKSGVCLLL

External Links

GenBank ID Protein

17026318

UniProtKB/Swiss-Prot ID

Q8WTQ7

UniProtKB/Swiss-Prot Entry Name

GRK7_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AF282269

GeneCard ID