| Identification |
| HMDB Protein ID
| CDBP04560 |
| Secondary Accession Numbers
| Not Available |
| Name
| Serine/threonine-protein kinase ULK2 |
| Description
| Not Available |
| Synonyms
|
- Unc-51-like kinase 2
|
| Gene Name
| ULK2 |
| Protein Type
| Enzyme |
| Biological Properties |
| General Function
| Involved in protein kinase activity |
| Specific Function
| ATP + a protein = ADP + a phosphoprotein |
| GO Classification
|
| Function |
| protein kinase activity |
| protein serine/threonine kinase activity |
| binding |
| catalytic activity |
| transferase activity |
| transferase activity, transferring phosphorus-containing groups |
| kinase activity |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| adenyl ribonucleotide binding |
| atp binding |
| protein binding |
| Process |
| phosphorylation |
| phosphorus metabolic process |
| phosphate metabolic process |
| metabolic process |
| cellular process |
| biological regulation |
| regulation of biological process |
| cellular metabolic process |
| cell projection organization |
| cell projection morphogenesis |
| neuron projection morphogenesis |
| axonogenesis |
| regulation of cellular process |
| signal transduction |
| protein amino acid phosphorylation |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
| Chromosome Location
| Chromosome:1 |
| Locus
| 17p11.2 |
| SNPs
| ULK2 |
| Gene Sequence
|
>3111 bp
ATGGAGGTGGTGGGTGACTTCGAGTACAGCAAGAGGGATCTCGTGGGACACGGGGCCTTC
GCCGTGGTCTTCCGGGGGCGGCACCGCCAGAAAACTGATTGGGAGGTAGCTATTAAAAGT
ATTAATAAAAAGAACTTGTCAAAATCACAAATACTGCTTGGAAAGGAAATTAAAATCTTA
AAGGAACTTCAGCATGAAAATATTGTAGCACTCTATGATGTTCAGGAATTACCCAACTCT
GTCTTTTTGGTGATGGAGTATTGCAATGGTGGAGACCTCGCAGATTATTTGCAAGCGAAA
GGGACTCTCAGTGAAGACACGATCAGAGTGTTTCTGCATCAGATTGCTGCTGCCATGCGA
ATCCTGCACAGCAAAGGAATCATCCACAGAGATCTCAAACCACAGAACATCTTGCTGTCC
TATGCCAATCGCAGAAAATCAAGTGTCAGTGGTATTCGCATCAAAATAGCGGATTTTGGT
TTTGCTCGTTACCTACATAGTAACATGATGGCTGCAACACTGTGTGGATCCCCGATGTAC
ATGGCTCCTGAGGTTATTATGTCTCAACATTATGATGCTAAGGCTGACTTGTGGAGCATA
GGAACAGTGATATACCAATGCCTAGTTGGAAAACCACCTTTTCAGGCCAATAGTCCTCAA
GACTTAAGGATGTTTTATGAAAAAAACAGGAGCTTAATGCCTAGTATTCCCAGAGAAACA
TCACCTTATTTGGCTAATCTCCTTTTGGGTTTGCTTCAGAGAAACCAAAAAGATAGAATG
GACTTTGAAGCATTTTTTAGCCATCCTTTTCTTGAGCAAGGTCCAGTAAAAAAATCTTGC
CCAGTTCCAGTGCCCATGTATTCTGGTTCTGTCTCTGGAAGCTCCTGTGGCAGCTCTCCA
TCTTGTCGTTTTGCTTCTCCACCATCCCTTCCAGATATGCAGCATATTCAGGAAGAAAAC
TTATCTTCCCCACCATTGGGTCCTCCCAACTATCTACAAGTTTCCAAAGATTCTGCCAGT
ACTAGTAGCAAGAACTCTTCTTGTGACACGGATGACTTTGTTTTGGTGCCACACAACATC
TCGTCAGACCACTCATGTGATATGCCAGTGGGGACTGCTGGCAGACGTGCTTCAAATGAA
TTCTTGGTGTGTGGAGGGCAGTGTCAGCCTACTGTGTCACCTCACAGCGAAACAGCACCA
ATTCCAGTTCCTACTCAAATAAGGAATTATCAGCGCATAGAGCAGAATCTTACATCTACT
GCCAGCTCAGGCACAAATGTACATGGTTCTCCAAGATCTGCAGTGGTACGAAGGTCCAAC
ACCAGCCCCATGGGCTTCCTCCGGCCGGGATCATGCTCCCCAGTACCAGCAGACACAGCA
CAGACAGTTGGACGAAGGCTCTCCACTGGGTCTTCTAGGCCTTACTCACCTTCCCCTTTG
GTTGGTACCATTCCTGAGCAATTCAGTCAGTGCTGCTGTGGGCATCCTCAGGGCCATGAC
TCCAGGAGTAGAAACTCCTCAGGTTCTCCAGTGCCACAAGCTCAGTCCCCACAGTCTCTC
TTATCGGGTGCTAGACTGCAGAGCGCCCCCACCCTCACTGACATCTATCAGAACAAGCAG
AAGCTCAGAAAACAGCACTCTGACCCCGTGTGCCCATCCCATACTGGGGCTGGGTACAGC
TACTCGCCTCAGCCCAGTCGGCCTGGCAGCCTTGGAACTTCTCCCACCAAGCACTTGGGG
TCCTCTCCACGGAGTTCTGACTGGTTCTTTAAAACTCCTTTGCCAACAATCATTGGCTCT
CCTACTAAGACCACAGCTCCTTTCAAAATCCCTAAAACTCAAGCATCTTCCAACCTGTTA
GCCTTGGTTACTCGTCATGGGCCTGCTGAAGAACAGTCGAAAGATGGGAATGAGCCACGG
GAATGTGCCCATTGCCTCTTAGTGCAAGGAAGTGAGAGGCAGCGGGCCGAGCAGCAGAGC
AAGGCAGTGTTTGGCAGATCTGTCAGTACCGGGAAGTTATCAGATCAACAAGGAAAGACT
CCTATATGTCGACATCAGGGCAGCACAGACAGTTTAAATACAGAACGACCAATGGATATA
GCTCCGGCAGGAGCCTGTGGTGGTGTTCTGGCACCTCCTGCAGGTACAGCAGCAAGTTCC
AAGGCTGTCCTCTTCACTGTAGGGTCTCCTCCACACAGTGCGGCAGCCCCCACTTGTACC
CACATGTTCCTTCGAACAAGAACAACCTCAGTGGGGCCCAGCAACTCCGGGGGCTCTCTT
TGTGCCATGAGTGGCCGCGTGTGCGTGGGGTCCCCGCCTGGCCCAGGCTTCGGCTCTTCC
CCTCCAGGAGCAGAGGCAGCTCCCAGCCTGAGATACGTGCCTTACGGTGCTTCACCCCCC
AGCCTAGAGGGGCTCATCACCTTTGAAGCCCCTGAACTGCCGGAGGAGACGCTGATGGAG
CGGGAACACACAGACACCTTACGCCATCTGAATGTGATGCTGATGTTCACTGAGTGTGTG
CTGGACCTGACAGCCATGAGGGGAGGAAACCCTGAGCTGTGCACATCTGCTGTGTCCTTG
TACCAGATCCAGGAGAGTGTGGTGGTGGACCAGATCAGTCAGCTGAGCAAAGACTGGGGG
CGGGTGGAGCAGCTGGTGTTGTACATGAAAGCAGCACAGCTGCTTGCGGCTTCTCTGCAT
CTTGCCAAAGCCCAGATCAAGTCCGGGAAACTGAGCCCATCCACAGCTGTGAAACAAGTT
GTCAAGAATCTGAACGAACGATATAAATTCTGCATCACCATGTGCAAGAAACTTACAGAA
AAGCTGAATCGATTCTTCTCTGACAAACAGAGGTTTATTGATGAAATCAACAGTGTGACT
GCAGAGAAACTCATCTATAATTGTGCTGTAGAAATGGTTCAGTCTGCAGCCCTGGATGAG
ATGTTTCAGCAGACCGAAGATATTGTTTATCGCTATCATAAGGCAGCCCTTCTTTTGGAA
GGCCTAAGTAGGATTCTACAGGACCCTGCAGATATTGAAAATGTGCATAAATATAAATGT
AGTATTGAGAGAAGACTGTCGGCGCTCTGCCATAGCACCGCAACCGTGTGA
|
| Protein Properties |
| Number of Residues
| 1036 |
| Molecular Weight
| 112693.2 |
| Theoretical pI
| 8.62 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Serine/threonine-protein kinase ULK2
MEVVGDFEYSKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKIL
KELQHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMR
ILHSKGIIHRDLKPQNILLSYANRRKSSVSGIRIKIADFGFARYLHSNMMAATLCGSPMY
MAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNRSLMPSIPRET
SPYLANLLLGLLQRNQKDRMDFEAFFSHPFLEQGPVKKSCPVPVPMYSGSVSGSSCGSSP
SCRFASPPSLPDMQHIQEENLSSPPLGPPNYLQVSKDSASTSSKNSSCDTDDFVLVPHNI
SSDHSCDMPVGTAGRRASNEFLVCGGQCQPTVSPHSETAPIPVPTQIRNYQRIEQNLTST
ASSGTNVHGSPRSAVVRRSNTSPMGFLRPGSCSPVPADTAQTVGRRLSTGSSRPYSPSPL
VGTIPEQFSQCCCGHPQGHDSRSRNSSGSPVPQAQSPQSLLSGARLQSAPTLTDIYQNKQ
KLRKQHSDPVCPSHTGAGYSYSPQPSRPGSLGTSPTKHLGSSPRSSDWFFKTPLPTIIGS
PTKTTAPFKIPKTQASSNLLALVTRHGPAEEQSKDGNEPRECAHCLLVQGSERQRAEQQS
KAVFGRSVSTGKLSDQQGKTPICRHQGSTDSLNTERPMDIAPAGACGGVLAPPAGTAASS
KAVLFTVGSPPHSAAAPTCTHMFLRTRTTSVGPSNSGGSLCAMSGRVCVGSPPGPGFGSS
PPGAEAAPSLRYVPYGASPPSLEGLITFEAPELPEETLMEREHTDTLRHLNVMLMFTECV
LDLTAMRGGNPELCTSAVSLYQIQESVVVDQISQLSKDWGRVEQLVLYMKAAQLLAASLH
LAKAQIKSGKLSPSTAVKQVVKNLNERYKFCITMCKKLTEKLNRFFSDKQRFIDEINSVT
AEKLIYNCAVEMVQSAALDEMFQQTEDIVYRYHKAALLLEGLSRILQDPADIENVHKYKC
SIERRLSALCHSTATV
|
| External Links |
| GenBank ID Protein
| 217330559 |
| UniProtKB/Swiss-Prot ID
| Q8IYT8 |
| UniProtKB/Swiss-Prot Entry Name
| ULK2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_001142610.1 |
| GeneCard ID
| ULK2 |
| GenAtlas ID
| ULK2 |
| HGNC ID
| HGNC:13480 |
| References |
| General References
| Not Available |